The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Zinc finger, CCCH-type
".
FunFam 2: Zinc finger protein 36, C3H1 type-like 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 34 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
|
16 |
P17431 (/IDA)
P22893 (/IDA)
P22893 (/IDA)
P23949 (/IDA)
P23950 (/IDA)
P23950 (/IDA)
P26651 (/IDA)
P47974 (/IDA)
P47980 (/IDA)
P47980 (/IDA)
(6 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
M0QY76 (/IPI)
M0QY76 (/IPI)
P22893 (/IPI)
P22893 (/IPI)
P23950 (/IPI)
P23950 (/IPI)
P26651 (/IPI)
P47974 (/IPI)
Q07352 (/IPI)
Q07352 (/IPI)
(2 more) |
|
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
|
11 |
A4IIN5 (/ISS)
P17431 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
Q805B4 (/ISS)
(1 more) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
9 | P17431 (/IDA) P22893 (/IDA) P22893 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
6 | P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | P26651 (/HDA) P47974 (/HDA) Q07352 (/HDA) Q07352 (/HDA) Q07352 (/HDA) |
|
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | P47974 (/ISM) Q07352 (/ISM) Q07352 (/ISM) Q07352 (/ISM) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
|
4 | P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
3 | Q07352 (/NAS) Q07352 (/NAS) Q07352 (/NAS) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
3 | P47973 (/IDA) P47980 (/IDA) P47980 (/IDA) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
3 | P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
|
3 | P23950 (/IMP) P23950 (/IMP) P26651 (/IMP) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q9C9F5 (/ISS) Q9C9F5 (/ISS) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
2 | P53781 (/ISS) Q6S9E0 (/ISS) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
2 | P53781 (/ISS) Q6S9E0 (/ISS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
C-C chemokine binding GO:0019957
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | Q9C9F5 (/IPI) Q9C9F5 (/IPI) |
|
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
|
2 | P22893 (/IDA) P22893 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q5ISE2 (/IDA) |
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q9C9N3 (/IPI) |
|
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
|
1 | P17431 (/IMP) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | P26651 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P26651 (/IPI) |
|
C-C chemokine binding GO:0019957
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
1 | P26651 (/IPI) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
1 | P26651 (/IDA) |
|
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
|
1 | P26651 (/TAS) |
There are 191 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
|
15 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
(5 more) |
|
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
15 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P53781 (/ISS)
(5 more) |
|
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
|
15 |
A4IIN5 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P26651 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P53781 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
(5 more) |
|
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
14 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
(4 more) |
|
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
|
14 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
(4 more) |
|
Cellular response to glucocorticoid stimulus GO:0071385
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
|
14 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
(4 more) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay GO:0031086
A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
|
13 |
A4IIN5 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
Q07352 (/ISS)
(3 more) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
12 |
A4IIN5 (/ISS)
P17431 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P26651 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
(2 more) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
12 |
A4IIN5 (/ISS)
P17431 (/ISS)
P23950 (/ISS)
P23950 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
(2 more) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
11 |
A4IIN5 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
Q805B4 (/ISS)
(1 more) |
|
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
11 |
P22893 (/IDA)
P22893 (/IDA)
P23949 (/IDA)
P23950 (/IDA)
P23950 (/IDA)
P26651 (/IDA)
P47980 (/IDA)
P47980 (/IDA)
Q07352 (/IDA)
Q07352 (/IDA)
(1 more) |
|
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
11 |
A4IIN5 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P23949 (/ISS)
P47973 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
Q805B4 (/ISS)
(1 more) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
10 | P17431 (/IDA) P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Regulation of B cell differentiation GO:0045577
Any process that modulates the frequency, rate or extent of B cell differentiation.
|
10 | A4IIN5 (/ISS) P17431 (/ISS) P47974 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Negative regulation of mitotic cell cycle phase transition GO:1901991
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.
|
10 | A4IIN5 (/ISS) P17431 (/ISS) P47974 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
9 | P22893 (/IMP) P22893 (/IMP) P23950 (/IMP) P23950 (/IMP) P26651 (/IMP) P47974 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
9 | P22893 (/IMP) P22893 (/IMP) P23950 (/IMP) P23950 (/IMP) P26651 (/IMP) P47974 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
9 | A4IIN5 (/ISS) P17431 (/ISS) P23949 (/ISS) P23950 (/ISS) P23950 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
9 | A4IIN5 (/ISS) P17431 (/ISS) P23949 (/ISS) P23950 (/ISS) P23950 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
8 | P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P23950 (/IDA) P23950 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
8 | P17431 (/ISS) P23949 (/ISS) P23950 (/ISS) P23950 (/ISS) P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Regulation of keratinocyte proliferation GO:0010837
Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
P38MAPK cascade GO:0038066
An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
8 | P17431 (/ISS) P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q6S9E0 (/ISS) |
|
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
8 | P17431 (/ISS) P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q6S9E0 (/ISS) |
|
Regulation of keratinocyte differentiation GO:0045616
Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
MRNA transport GO:0051028
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Regulation of keratinocyte apoptotic process GO:1902172
Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
|
7 | P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) Q5ISE2 (/IDA) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
7 | P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
|
7 | P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) P47974 (/IDA) |
|
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
7 | P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
|
7 | P17431 (/IDA) P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P26651 (/IDA) Q7ZXW9 (/IDA) Q7ZXW9 (/IDA) |
|
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Somatic stem cell division GO:0048103
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
6 | A4IIN5 (/ISS) P47974 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
5 | P22893 (/IMP) P22893 (/IMP) P23950 (/IMP) P23950 (/IMP) P26651 (/IMP) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
|
5 | A4IIN5 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) Q805B4 (/ISS) Q805B4 (/ISS) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Regulation of tumor necrosis factor production GO:0032680
Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Negative regulation of viral transcription GO:0032897
Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
T cell differentiation in thymus GO:0033077
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
|
5 | P17431 (/ISS) P47974 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
3'-UTR-mediated mRNA destabilization GO:0061158
An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
5 | P23950 (/IDA) P23950 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
|
5 | P26651 (/IDA) P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to peptide hormone stimulus GO:0071375
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
5 | P23950 (/IDA) P23950 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to glucocorticoid stimulus GO:0071385
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
|
5 | P26651 (/IDA) P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to glucocorticoid stimulus GO:0071385
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
|
5 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA GO:1901835
Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Positive regulation of gene silencing by miRNA GO:2000637
Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Regulation of keratinocyte proliferation GO:0010837
Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
|
4 | P26651 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
Regulation of keratinocyte proliferation GO:0010837
Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay GO:0031086
A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
|
4 | P17431 (/IDA) P26651 (/IDA) Q7ZXW9 (/IDA) Q7ZXW9 (/IDA) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-independent decay GO:0031086
A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
MiRNA mediated inhibition of translation GO:0035278
The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs
|
4 | P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
P38MAPK cascade GO:0038066
An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
4 | P22893 (/IDA) P22893 (/IDA) P23950 (/IDA) P23950 (/IDA) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
4 | P26651 (/TAS) Q07352 (/TAS) Q07352 (/TAS) Q07352 (/TAS) |
|
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Negative regulation of interleukin-2 biosynthetic process GO:0045085
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
|
4 | P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
4 | P22893 (/IDA) P22893 (/IDA) P23950 (/IDA) P23950 (/IDA) |
|
Regulation of keratinocyte differentiation GO:0045616
Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
|
4 | P26651 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
Regulation of keratinocyte differentiation GO:0045616
Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
4 | P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Regulation of myoblast differentiation GO:0045661
Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Mesendoderm development GO:0048382
The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
MRNA transport GO:0051028
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | P26651 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
MRNA transport GO:0051028
The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
4 | P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
4 | P47974 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Regulation of stem cell proliferation GO:0072091
Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Cellular response to raffinose GO:0097403
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
|
4 | P17431 (/ISS) Q07352 (/ISS) Q07352 (/ISS) Q07352 (/ISS) |
|
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Regulation of keratinocyte apoptotic process GO:1902172
Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.
|
4 | P26651 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
Regulation of keratinocyte apoptotic process GO:1902172
Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Negative regulation of polynucleotide adenylyltransferase activity GO:1904246
Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.
|
4 | P26651 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
|
4 | P26651 (/IMP) Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
Positive regulation of intracellular mRNA localization GO:1904582
Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P22893 (/IMP) P22893 (/IMP) P26651 (/IMP) |
|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
3 | P22893 (/IDA) P22893 (/IDA) Q5ISE2 (/IDA) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
3 | P17431 (/IDA) P23949 (/IDA) P26651 (/IDA) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
3 | Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
3 | Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
|
3 | Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
3 | Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
T cell differentiation in thymus GO:0033077
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
|
3 | P23949 (/IGI) P23950 (/IGI) P23950 (/IGI) |
|
T cell differentiation in thymus GO:0033077
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
|
3 | P23949 (/IMP) P23950 (/IMP) P23950 (/IMP) |
|
Cellular response to fibroblast growth factor stimulus GO:0044344
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
|
3 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) |
|
Regulation of B cell differentiation GO:0045577
Any process that modulates the frequency, rate or extent of B cell differentiation.
|
3 | P23949 (/IMP) P23950 (/IMP) P23950 (/IMP) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
3 | Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
|
3 | A4IIN5 (/ISS) Q7ZXW9 (/ISS) Q7ZXW9 (/ISS) |
|
Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
|
3 | P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) |
|
Positive regulation of mRNA catabolic process GO:0061014
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
|
3 | P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
3 | P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
3 | P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
3 | P22893 (/IMP) P22893 (/IMP) P26651 (/IMP) |
|
Cellular response to peptide hormone stimulus GO:0071375
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
3 | Q07352 (/IMP) Q07352 (/IMP) Q07352 (/IMP) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
3 | P17431 (/ISS) P23950 (/ISS) P23950 (/ISS) |
|
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
3 | P23949 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
3 | P22893 (/ISO) P22893 (/ISO) P23949 (/ISO) |
|
Negative regulation of mitotic cell cycle phase transition GO:1901991
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.
|
3 | P23949 (/IMP) P23950 (/IMP) P23950 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Proepicardium development GO:0003342
The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q9C9F5 (/TAS) Q9C9F5 (/TAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | P22893 (/IGI) P22893 (/IGI) |
|
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P47980 (/IDA) P47980 (/IDA) |
|
Phosphatidylinositol 3-kinase signaling GO:0014065
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
RNA interference GO:0016246
The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
|
2 | P47980 (/IMP) P47980 (/IMP) |
|
Neural tube development GO:0021915
The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Regulation of tumor necrosis factor production GO:0032680
Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Negative regulation of viral transcription GO:0032897
Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
MiRNA mediated inhibition of translation GO:0035278
The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs
|
2 | P22893 (/IDA) P22893 (/IDA) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | P22893 (/IDA) P22893 (/IDA) |
|
Pronephric nephron tubule development GO:0039020
The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.
|
2 | Q805B4 (/IMP) Q805B4 (/IMP) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Protein kinase B signaling GO:0043491
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Negative regulation of interleukin-2 biosynthetic process GO:0045085
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Regulation of myoblast differentiation GO:0045661
Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Mesendoderm development GO:0048382
The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
|
2 | P23950 (/IDA) P23950 (/IDA) |
|
Embryonic organ development GO:0048568
Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
|
2 | Q805B4 (/IMP) Q805B4 (/IMP) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
RNA destabilization GO:0050779
Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:0060213
Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Chorio-allantoic fusion GO:0060710
The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Spongiotrophoblast layer development GO:0060712
The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Positive regulation of mRNA catabolic process GO:0061014
Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to peptide hormone stimulus GO:0071375
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | P23950 (/ISO) P23950 (/ISO) |
|
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
2 | P23950 (/IDA) P23950 (/IDA) |
|
Nephron tubule development GO:0072080
The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
|
2 | Q805B4 (/IMP) Q805B4 (/IMP) |
|
Regulation of stem cell proliferation GO:0072091
Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
2 | P23950 (/IDA) P23950 (/IDA) |
|
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
|
2 | P26651 (/IDA) P47974 (/IDA) |
|
Cellular response to raffinose GO:0097403
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
|
2 | P23950 (/IDA) P23950 (/IDA) |
|
Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900153
Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
|
2 | P47980 (/IMP) P47980 (/IMP) |
|
Positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA GO:1901835
Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Negative regulation of polynucleotide adenylyltransferase activity GO:1904246
Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.
|
2 | P22893 (/IMP) P22893 (/IMP) |
|
Positive regulation of gene silencing by miRNA GO:2000637
Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
1 | P26651 (/IMP) |
|
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
|
1 | P26651 (/TAS) |
|
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
1 | P23949 (/IMP) |
|
Regulation of tumor necrosis factor production GO:0032680
Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.
|
1 | P26651 (/IDA) |
|
Negative regulation of viral transcription GO:0032897
Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
|
1 | P26651 (/IMP) |
|
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
|
1 | P23949 (/IMP) |
|
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
|
1 | P26651 (/IDA) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
1 | P23949 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9C9N3 (/IDA) |
|
Somatic stem cell division GO:0048103
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
|
1 | P23949 (/IMP) |
|
Negative regulation of unidimensional cell growth GO:0051511
Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one
|
1 | Q9C9N3 (/IMP) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
1 | P23949 (/IMP) |
|
3'-UTR-mediated mRNA stabilization GO:0070935
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
|
1 | P26651 (/IDA) |
|
Negative regulation of secondary cell wall biogenesis GO:1901347
Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.
|
1 | Q9C9N3 (/IMP) |
|
Positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA GO:1901835
Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
|
1 | P26651 (/IDA) |
|
Positive regulation of gene silencing by miRNA GO:2000637
Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.
|
1 | P26651 (/IMP) |
|
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
|
1 | P23949 (/IMP) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
14 |
A4IIN5 (/ISS)
P17431 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P47980 (/ISS)
P47980 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
(4 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
11 |
P22893 (/IDA)
P22893 (/IDA)
P23949 (/IDA)
P23950 (/IDA)
P23950 (/IDA)
P26651 (/IDA)
P47973 (/IDA)
Q07352 (/IDA)
Q07352 (/IDA)
Q07352 (/IDA)
(1 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
11 |
A4IIN5 (/ISS)
P22893 (/ISS)
P22893 (/ISS)
P47973 (/ISS)
P47974 (/ISS)
P53781 (/ISS)
Q6S9E0 (/ISS)
Q7ZXW9 (/ISS)
Q7ZXW9 (/ISS)
Q805B4 (/ISS)
(1 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | P22893 (/IDA) P22893 (/IDA) P23949 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) P47973 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
8 | P22893 (/IDA) P22893 (/IDA) P23950 (/IDA) P23950 (/IDA) P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
8 | P17431 (/ISS) P22893 (/ISS) P22893 (/ISS) P23950 (/ISS) P23950 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
5 | P22893 (/ISS) P22893 (/ISS) P47973 (/ISS) P53781 (/ISS) Q6S9E0 (/ISS) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
4 | P26651 (/IDA) Q07352 (/IDA) Q07352 (/IDA) Q07352 (/IDA) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P17431 (/IDA) P22893 (/IDA) P22893 (/IDA) P26651 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P26651 (/TAS) Q07352 (/TAS) Q07352 (/TAS) Q07352 (/TAS) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
4 | P22893 (/ISO) P22893 (/ISO) P23950 (/ISO) P23950 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P47980 (/HDA) P47980 (/HDA) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
2 | P22893 (/ISO) P22893 (/ISO) |
|
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
|
2 | Q20155 (/HDA) Q7YXD9 (/HDA) |
|
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
|
2 | P23950 (/IMP) P23950 (/IMP) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P26651 (/TAS) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
1 | P26651 (/IDA) |