The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Hect, E3 ligase catalytic domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
997
3D
4be8A01 - 90.7
2
782
3D
1nd7A01 - 89.0
3
596 - - 95.8
4
547 - - 76.0
5
538
3D
3olmA01 - 76.1
6
422 - - 67.7
7
420
3D
1zvdA01 - 81.3
8
392 - - 83.9
9
381
3D
3h1dA01 - 69.1
10
366 - - 68.9
11
340 - - 90.4
12
296 - - 93.4
13
285 - - 82.5
14
262 - - 94.2
16
252 - - 51.1
15
252 - - 71.9
17
243 - - 70.5
18
238 - - 72.2
19
228 - - 64.7
20
191 - - 30.6
21
187 - - 75.5
22
157 - - 42.9
23
140 - - 83.0
24
124 - - 49.6
25
108 - - 77.4
26
85 - - 99.0
27
83 - - 64.4
28
76 - - 84.1
29
52 - - 37.0
30
44 - - 47.2
31
35 - - 78.4
32
32 - - 72.5
33
28 - - 72.8
34
28 - - 11.9
36
25 - - 70.8
35
25 - - 37.1
37
18 - - 23.7
38
18 - - 7.4
39
17 - - 93.1
40
15 - - 1.7
41
E3
14 - - 80.0
43
14 - - 7.8
42
14 - - 38.2
44
12 - - 75.1
45
11 - - 42.7
48
10 - - 66.7
46
10 - - 54.9
47
10 - - 24.3
49
9 - - 36.2
50
9 - - 8.3
51
8 - - 12.5
52
Ubiquitin-transferase
8 - - 11.7
53
7 - - 1.6
55
7 - - 11.6
54
7 - - 12.9
56
6 - - 0.7
58
6 - - 94.6
57
Ubiquitin-transferase
6 - - 40.8
60
5 - - 11.1
59
5 - - 80.0
61
4 - - 16.8
69
3 - - 14.2
62
3 - - 44.2
71
3 - - 0.0
65
3 - - 6.4
72
3 - - 44.9
67
3 - - 71.7
68
3 - - 43.7
63
3 - - 19.9
79
3 - - 38.2
70
3 - - 0.0
64
3 - - 10.5
66
3 - - 36.7
78
2 - - 36.6
80
2 - - 51.6
82
2 - - 0.7
76
2 - - 25.6
84
2 - - 0.0
85
2 - - 39.8
74
2 - - 0.0
81
2 - - 18.7
77
2 - - 27.0
83
Ubiquitin-transferase
2 - - 0.0
75
2 - - 29.3
73
2 - - 5.3
112
1 - - 0.0
89
1 - - 0.0
92
1 - - 0.0
105
1 - - 0.0
99
1 - - 0.0
90
1 - - 0.0
110
1 - - 0.0
103
1 - - 0.0
96
1 - - 0.0
117
1 - - 0.0
94
1 - - 0.0
109
1 - - 0.0
98
1 - - 0.0
107
1 - - 0.0
87
1 - - 0.0
115
1 - - 0.0
91
1 - - 0.0
111
1 - - 0.0
113
1 - - 0.0
102
1 - - 0.0
118
1 - - 0.0
100
1 - - 0.0
93
1 - - 0.0
101
1 - - 0.0
116
1 - - 0.0
108
1 - - 0.0
95
1 - - 0.0
106
1 - - 0.0
86
1 - - 0.0
114
1 - - 0.0
104
1 - - 0.0
97
1 - - 0.0
88
1 - - 0.0
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