The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"von Willebrand factor, type A domain
".
FunFam 43: Protein transport protein SEC23
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q38AJ0 (/IPI) Q580Y6 (/IPI) Q580Y6 (/IPI) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
2 | Q580Y6 (/ISA) Q580Y6 (/ISA) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q95TD2 (/ISS) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
3 | Q38AJ0 (/IMP) Q580Y6 (/IMP) Q580Y6 (/IMP) |
Positive regulation of extracellular matrix constituent secretion GO:0003331
Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
|
1 | Q95TD2 (/IMP) |
Regulation of COPII vesicle coating GO:0003400
Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
1 | Q95TD2 (/ISS) |
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
|
1 | Q95TD2 (/IMP) |
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
1 | Q95TD2 (/IGI) |
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
1 | Q95TD2 (/IMP) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
1 | Q95TD2 (/IMP) |
Larval chitin-based cuticle development GO:0008363
Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
|
1 | Q95TD2 (/IMP) |
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
1 | Q95TD2 (/IMP) |
Positive regulation of cell-cell adhesion GO:0022409
Any process that activates or increases the rate or extent of cell adhesion to another cell.
|
1 | Q95TD2 (/IMP) |
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
|
1 | Q95TD2 (/IMP) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
1 | Q95TD2 (/IMP) |
Lumen formation, open tracheal system GO:0035149
Creation of the central hole of a tube in an open tracheal system through which gases flow.
|
1 | Q95TD2 (/IMP) |
Chitin-based larval cuticle pattern formation GO:0035293
The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.
|
1 | Q95TD2 (/IMP) |
Chitin-based cuticle development GO:0040003
Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
|
1 | Q95TD2 (/IMP) |
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | Q95TD2 (/ISS) |
Positive regulation of cuticle pigmentation GO:0048081
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
|
1 | Q95TD2 (/IMP) |
Golgi membrane coat protein complex assembly GO:0048197
The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.
|
1 | Q4Q0B5 (/ISO) |
Positive regulation of dendrite morphogenesis GO:0050775
Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
|
1 | Q95TD2 (/IMP) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
1 | Q95TD2 (/IMP) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q95TD2 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
3 | Q38AJ0 (/IDA) Q580Y6 (/IDA) Q580Y6 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
3 | Q38AJ0 (/IMP) Q580Y6 (/IMP) Q580Y6 (/IMP) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
2 | Q38AJ0 (/IDA) Q95TD2 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q95TD2 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q4Q0B5 (/ISO) |
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
|
1 | Q95TD2 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
1 | Q95TD2 (/ISS) |
COPII-coated ER to Golgi transport vesicle GO:0030134
A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
|
1 | Q95TD2 (/TAS) |