The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
von Willebrand factor, type A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1555 - - 93.2
2
1287
3D
5ffoF00 - 92.4
3
1237 - - 99.1
4
VI
1145 - - 99.1
5
589
3D
2x5nA01 - 87.8
6
540 - - 75.6
7
482 - - 90.4
8
456
3D
2qtvA03 - 91.3
12
456
3D
6ndhR00 - 96.5
9
432 - - 91.3
11
415
3D
5vnoA03 - 79.7
10
410 - - 94.7
13
342 - - 84.2
14
279 - - 60.3
15
278
3D
4wfqA00 - 92.0
17
271
3D
6cx1E00 - 71.7
16
269 - - 97.2
18
246 - - 83.0
19
238
3D
5vnoB04 - 76.6
20
220
3D
5kyyB04 - 86.7
21
207 - - 97.9
22
206 - - 84.0
23
190
3D
4ihkA00 - 73.1
24
190
3D
1t6bY00 - 96.4
25
176 - - 74.5
26
162 - - 93.8
27
VI
159 - - 84.3
31
156
3D
6erhC01 - 87.9
28
156 - - 90.5
29
148 - - 89.2
30
147 - - 4.7
33
145
3D
2i91B01 - 93.3
32
144 - - 68.7
34
138 - - 89.2
35
VI
135 - - 78.7
36
132 - - 79.2
37
131 - - 65.6
38
126 - - 71.8
39
125 - - 72.6
40
120 - - 78.4
41
XXI
117 - - 74.1
42
117 - - 48.8
43
102 - - 96.1
44
100 - - 87.5
45
95 - - 83.9
46
86 - - 82.5
47
84 - - 96.6
48
77 - - 47.4
56
76
3D
2xwjL03 - 68.1
53
75
3D
3zqkC00 - 49.8
49
75 - - 35.3
50
71 - - 78.5
61
70
3D
5bv8A00 - 48.7
51
68 - - 93.2
55
68
3D
6erfD01 - 88.4
52
VI
67 - - 87.0
54
66 - - 93.9
57
59 - - 52.8
63
59
3D
4dmuL00 - 46.7
58
56 - - 83.1
59
56 - - 80.9
60
53 - - 78.3
62
49 - - 66.8
65
46
3D
2i6sA01 - 31.9
64
45 - - 80.0
66
39 - - 37.6
67
38 - - 75.4
68
36 - - 74.2
69
36 - - 51.4
70
35 - - 30.1
71
34 - - 84.5
72
VII
33 - - 76.9
73
29 - - 89.8
74
28 - - 16.5
81
28
3D
1pd1A04 - 59.6
75
28
3D
4hqfA00 - 16.2
76
26 - - 71.6
77
25 - - 18.7
78
24 - - 26.3
80
24 - - 90.7
84
24
3D
5obzA00 - 79.2
79
24 - - 29.6
82
23 - - 95.1
83
22 - - 35.4
85
20 - - 5.2
86
20 - - 8.1
87
19 - - 6.9
88
19 - - 4.8
89
18 - - 4.0
91
18 - - 1.9
90
18 - - 19.6
92
17 - - 74.9
94
17 - - 2.9
95
17 - - 72.4
93
17 - - 80.3
96
16 - - 47.0
97
16 - - 16.4
98
15 - - 83.0
101
14 - - 66.2
99
14 - - 85.0
100
14 - - 49.1
102
13 - - 78.4
103
12 - - 8.6
108
11 - - 9.7
105
11 - - 38.7
109
11 - - 78.1
106
11 - - 63.7
107
11 - - 2.9
104
11 - - 20.0
112
10 - - 40.6
111
10 - - 92.2
113
10 - - 7.0
110
10 - - 41.9
114
10 - - 73.9
116
9 - - 24.4
117
9 - - 8.7
120
9 - - 93.6
121
9 - - 4.6
119
9 - - 72.9
115
9 - - 36.5
118
9 - - 74.7
127
8 - - 85.1
128
AFU_orthologue AFUA_2G15070
8 - - 46.3
124
8 - - 4.5
122
8 - - 20.2
125
8 - - 0.6
126
8 - - 12.4
123
8 - - 5.8
132
7 - - 14.7
129
7 - - 70.9
131
7 - - 7.3
130
7 - - 8.3
133
7 - - 36.8
134
7 - - 78.1
136
6 - - 88.5
137
6 - - 34.5
142
6 - - 42.9
139
6 - - 15.8
135
6 - - 76.0
141
6 - - 57.5
138
6 - - 14.7
140
Fragment
6 - - 89.7
145
5 - - 94.3
146
5 - - 89.5
144
5 - - 11.6
143
5 - - 11.8
153
4 - - 14.5
155
4 - - 12.0
154
4 - - 3.6
158
4 - - 71.0
147
4 - - 69.9
149
4 - - 63.5
152
4 - - 12.2
148
4 - - 68.3
157
4 - - 77.6
151
4 - - 11.0
156
4 - - 52.9
150
4 - - 11.6
159
4 - - 34.8
180
3 - - 8.7
170
3 - - 3.1
175
3 - - 2.1
184
3 - - 28.8
181
3 - - 8.8
165
3 - - 73.7
168
3 - - 8.9
178
3 - - 20.9
161
3 - - 16.8
174
3 - - 13.7
183
3 - - 22.5
179
3 - - 0.8
164
3 - - 47.7
160
3 - - 21.8
177
3 - - 69.6
182
3 - - 2.1
167
3 - - 3.1
163
3 - - 20.8
186
3 - - 68.4
173
3 - - 5.2
171
3 - - 5.0
176
3 - - 38.9
162
3 - - 29.9
169
3 - - 7.4
172
3 - - 3.9
166
3 - - 9.4
185
3 - - 70.1
246
2 - - 8.1
191
2 - - 28.2
187
2 - - 2.1
262
2 - - 38.1
212
2 - - 10.2
232
2 - - 9.0
225
2 - - 12.0
207
2 - - 0.0
257
2 - - 2.3
198
2 - - 49.9
202
2 - - 0.5
229
2 - - 31.7
222
2 - - 6.0
217
2 - - 0.0
247
2 - - 0.0
209
2 - - 0.6
210
2 - - 0.0
252
2 - - 0.0
242
2 - - 0.0
254
2 - - 0.0
213
2 - - 0.0
200
2 - - 41.2
224
2 - - 3.5
263
2 - - 40.8
192
2 - - 28.1
267
2 - - 41.0
233
2 - - 0.0
199
2 - - 37.5
195
2 - - 29.2
188
2 - - 0.0
243
2 - - 12.9
203
2 - - 0.0
204
2 - - 0.0
228
2 - - 12.5
238
2 - - 0.0
253
2 - - 0.0
258
2 - - 0.0
248
2 - - 0.0
211
2 - - 0.0
236
2 - - 0.0
218
2 - - 0.0
234
2 - - 0.0
193
2 - - 30.7
189
2 - - 6.1
221
2 - - 0.0
260
2 - - 34.8
205
2 - - 0.0
227
XIV
2 - - 11.2
264
2 - - 40.6
255
2 - - 12.6
250
2 - - 0.0
259
2 - - 11.4
249
2 - - 0.0
240
2 - - 2.7
230
2 - - 37.8
214
2 - - 0.0
239
2 - - 0.0
219
2 - - 4.2
196
2 - - 39.7
206
2 - - 0.0
194
2 - - 28.8
220
2 - - 0.0
226
2 - - 10.0
244
2 - - 7.4
237
2 - - 1.4
235
2 - - 0.0
265
2 - - 40.6
197
2 - - 42.8
251
2 - - 0.0
256
2 - - 2.0
215
2 - - 0.0
245
2 - - 2.4
208
2 - - 0.0
241
2 - - 9.6
201
2 - - 45.1
266
2 - - 42.9
190
2 - - 14.7
231
2 - - 47.2
261
2 - - 31.9
223
2 - - 0.0
216
2 - - 0.0
350
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
285
1 - - 0.0
308
1 - - 0.0
301
1 - - 0.0
366
1 - - 0.0
272
1 - - 0.0
294
1 - - 0.0
349
1 - - 0.0
323
1 - - 0.0
359
1 - - 0.0
330
1 - - 0.0
360
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
278
1 - - 0.0
361
1 - - 0.0
307
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
299
1 - - 0.0
315
1 - - 0.0
305
1 - - 0.0
281
1 - - 0.0
317
1 - - 0.0
284
1 - - 0.0
289
1 - - 0.0
319
1 - - 0.0
344
1 - - 0.0
336
1 - - 0.0
290
1 - - 0.0
365
1 - - 0.0
271
1 - - 0.0
367
1 - - 0.0
351
1 - - 0.0
342
1 - - 0.0
341
1 - - 0.0
309
1 - - 0.0
329
1 - - 0.0
346
1 - - 0.0
279
1 - - 0.0
372
1 - - 0.0
293
1 - - 0.0
322
1 - - 0.0
310
1 - - 0.0
354
1 - - 0.0
316
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
314
1 - - 0.0
355
1 - - 0.0
334
1 - - 0.0
302
1 - - 0.0
362
BTF
1 - - 0.0
376
1 - - 0.0
298
1 - - 0.0
371
1 - - 0.0
339
1 - - 0.0
268
1 - - 0.0
345
1 - - 0.0
318
1 - - 0.0
356
1 - - 0.0
325
1 - - 0.0
378
1 - - 0.0
337
1 - - 0.0
288
1 - - 0.0
373
1 - - 0.0
287
1 - - 0.0
333
1 - - 0.0
274
1 - - 0.0
303
1 - - 0.0
276
1 - - 0.0
347
1 - - 0.0
320
1 - - 0.0
377
1 - - 0.0
338
1 - - 0.0
328
1 - - 0.0
269
1 - - 0.0
363
1 - - 0.0
313
2
1 - - 0.0
357
1 - - 0.0
297
1 - - 0.0
283
1 - - 0.0
358
1 - - 0.0
331
1 - - 0.0
348
1 - - 0.0
364
1 - - 0.0
324
1 - - 0.0
379
1 - - 0.0
295
1 - - 0.0
312
1 - - 0.0
370
1 - - 0.0
380
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
296
1 - - 0.0
275
1 - - 0.0
352
1 - - 0.0
369
1 - - 0.0
332
S. cerevisiae
1 - - 0.0
368
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
374
1 - - 0.0
327
1 - - 0.0
270
1 - - 0.0
343
1 - - 0.0
321
1 - - 0.0
282
1 - - 0.0
277
1 - - 0.0
304
1 - - 0.0
306
1 - - 0.0