The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"von Willebrand factor, type A domain
".
FunFam 124: ATP-dependent DNA helicase II subunit 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q04437 (/IPI) Q04437 (/IPI) Q04437 (/IPI) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |
|
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Chromatin assembly or disassembly GO:0006333
The formation or destruction of chromatin structures.
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |
|
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Donor selection GO:0007535
The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |
|
Donor selection GO:0007535
The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
|
3 | Q04437 (/IGI) Q04437 (/IGI) Q04437 (/IGI) |
|
Donor selection GO:0007535
The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Protein localization to chromosome GO:0034502
Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
|
3 | Q04437 (/IGI) Q04437 (/IGI) Q04437 (/IGI) |
|
Establishment of protein-containing complex localization to telomere GO:0097695
The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
3 | Q04437 (/IMP) Q04437 (/IMP) Q04437 (/IMP) |
|
Ku70:Ku80 complex GO:0043564
Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
|
3 | Q04437 (/IDA) Q04437 (/IDA) Q04437 (/IDA) |