The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
von Willebrand factor, type A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 116: Voltage-dependent calcium channel unc-36

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
2 G4S4A1 (/IMP) P34374 (/IMP)
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
1 P34374 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Serotonin receptor signaling pathway GO:0007210
The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Protein localization to synapse GO:0035418
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
2 G4S4A1 (/IMP) P34374 (/IMP)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
2 G4S4A1 (/IMP) P34374 (/IMP)
Pharyngeal pumping GO:0043050
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 G4S4A1 (/IMP) P34374 (/IMP)
Serotonin receptor signaling pathway GO:0007210
The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
1 P34374 (/IMP)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
1 P34374 (/IMP)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
1 P34374 (/IMP)
Pharyngeal pumping GO:0043050
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
1 P34374 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 G4S4A1 (/IDA) P34374 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 G4S4A1 (/IDA) P34374 (/IDA)
Voltage-gated calcium channel complex GO:0005891
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
2 A8XP97 (/ISS) E3LT28 (/ISS)
Voltage-gated calcium channel complex GO:0005891
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
1 P34374 (/IDA)
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