The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 46: Phosphomannomutase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphomannomutase activity GO:0004615
Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
16 P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA)
(6 more)
Phosphomannomutase activity GO:0004615
Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
8 O15305 (/TAS) O15305 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O15305 (/IPI) O15305 (/IPI) Q92871 (/IPI) Q92871 (/IPI) Q92871 (/IPI) Q92871 (/IPI) Q92871 (/IPI) Q92871 (/IPI)
Phosphomannomutase activity GO:0004615
Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
3 O35621 (/ISO) O35621 (/ISO) Q9UTJ2 (/ISO)
Phosphomannomutase activity GO:0004615
Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
2 P31353 (/IGI) P31353 (/IGI)
Phosphomannomutase activity GO:0004615
Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
2 O35621 (/ISS) O35621 (/ISS)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein targeting to ER GO:0045047
The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
10 P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP) P07283 (/IMP)
GDP-mannose biosynthetic process GO:0009298
The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
8 O15305 (/TAS) O15305 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS)
Mannose metabolic process GO:0006013
The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
6 Q92871 (/IDA) Q92871 (/IDA) Q92871 (/IDA) Q92871 (/IDA) Q92871 (/IDA) Q92871 (/IDA)
Mannose metabolic process GO:0006013
The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
6 Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS)
Mannose metabolic process GO:0006013
The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
2 O35621 (/ISO) O35621 (/ISO)
Mannose metabolic process GO:0006013
The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
2 O35621 (/ISS) O35621 (/ISS)
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
2 O15305 (/TAS) O15305 (/TAS)
Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
2 O35621 (/IEP) O35621 (/IEP)
Protein N-linked glycosylation GO:0006487
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
1 Q7ZTZ3 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
1 Q7ZTZ3 (/IMP)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
1 Q7ZTZ3 (/IMP)
Chondrocyte morphogenesis GO:0090171
The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
1 Q7ZTZ3 (/IGI)
Chondrocyte morphogenesis GO:0090171
The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
1 Q7ZTZ3 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 A0A0S2Z4J6 (/IDA) A0A0S2Z4J6 (/IDA) H3BV55 (/IDA) O15305 (/IDA) O15305 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA)
(5 more)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
10 P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA) P07283 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 O15305 (/TAS) O15305 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS) Q92871 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A0A0S2Z4J6 (/IDA) A0A0S2Z4J6 (/IDA) H3BV55 (/IDA) O15305 (/IDA) O15305 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 O35621 (/IDA) O35621 (/IDA) Q9Z2M7 (/IDA) Q9Z2M7 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
4 O35621 (/IDA) O35621 (/IDA) Q9Z2M7 (/IDA) Q9Z2M7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9Z2M7 (/ISO) Q9Z2M7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9Z2M7 (/ISO) Q9Z2M7 (/ISO)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
2 P31353 (/IDA) P31353 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UTJ2 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UTJ2 (/HDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...