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CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1HAD hydrolase, family IBHAD family hydrolasePhosphoserine phosphatasePhosphoserine phosphatase, chloroplasticEnolase-phosphatase E1N-acylneuraminate cytidylyltransferase AEnolase-phosphatase E1HAD hydrolase, family IASDT1p Pyrimidine nucleotidaseHydrolase, haloacid dehalogenase-like familyHydrolase, haloacid dehalogenase-like familySC:2Calcium-transporting ATPase 1Haloacid dehalogenase-like hydrolase family proteinCopper-exporting P-type ATPasePhosphatase yihXPhosphonoacetaldehyde hydrolasePutative transferasePhosphoserine phosphatase ThrHBifunctional epoxide hydrolase 2N-acylneuraminate-9-phosphataseCopper-exporting P-type ATPase B3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsCHydrolase, haloacid dehalogenase-like familyATPase 2, plasma membrane-typeSC:3HAD-IIA family hydrolaseSugar phosphatase YfbTD,D-heptose 1,7-bisphosphate phosphataseHistidine biosynthesis bifunctional protein HisBPutative Phosphatidyl synthasePhospholysine phosphohistidine inorganic pyrophosphate phosphataseProbable phosphataseHaloacid dehalogenase-like hydrolase domain-containing protein 2SC:4HAD family hydrolasePhospholysine phosphohistidine inorganic pyrophosphate phosphataseHaloacid dehalogenase-like hydrolase domain-containing protein 2glycerol-3-phosphate phosphatasePyridoxal phosphate phosphatasePredicted phosphatasePROBABLE PHOSPHATASESC:5Acid phosphataseSC:6PhosphomannomutaseClass B acid phosphatasePhosphomannomutaseTrehalose-phosphatasePhosphomannomutaseSC:7Carboxy-terminal domain RNA polymerase II polypeptide A smallMitochondrial import inner membrane translocase subunit TIM50Ubiquitin-like domain-containing CTD phosphatase 1Related to FCP1-TFIIF interacting component of CTD phosphataseSC:8Phosphoserine phosphatase SerBPhosphoserine phosphatase SerBPhospholipid-transporting ATPase ICPotassium-transporting ATPase ATP-binding subunitHAD-IIB family hydrolaseSodium/potassium-transporting ATPase subunit alphaPlasma membrane ATPaseCalcium-transporting ATPasePlasma membrane ATPasePhospholipid-transporting ATPasePhospholipid-transporting ATPaseCalcium-transporting ATPasePhospholipid-transporting ATPasePhospholipid-transporting ATPaseCTD small phosphatase-like protein 2Calcium-transporting ATPaseCalcium-transporting ATPaseProbable cation-transporting P-type ATPaseNT5C2 isoform 1Phosphoglycolate phosphatasePhospholipid-transporting ATPasePhosphoglycolate phosphataseNT5DC3 isoform 1ATPase copper transporting betaCalcium-transporting P-type ATPase, putative3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsCProbable copper-transporting ATPase HMA5Cytosolic 5-nucleotidase 3-likePhospholipid-transporting ATPaseRNA polymerase II C-terminal domain phosphatase-like 1Fructose-1-phosphate/6-phosphogluconate phosphatasePhosphoglycolate phosphataseRNA polymerase II subunit A C-terminal domain phosphataseHAD hydrolase, family IFGeneral stress response phosphoprotein phosphatase Psr1/2CTD nuclear envelope phosphatase 1Cation-transporting ATPaseSodium P-type ATPaseAlpha,alpha-trehalose-phosphate synthase [UDP-forming] 6TIGR01457 family HAD hydrolasealpha,alpha-trehalose-phosphate synthase [UDP-forming] 6Cation-transporting ATPaseHAD family hydrolaseCation-transporting ATPase INuclear elongation and deformation proteinHAD hydrolase, family IAHAD phosphatase, family IIIACation-transporting ATPaseHAD-superfamily subfamily IIA hydrolaseHAD hydrolase, family IACation-transporting ATPaseTrehalose 6-phosphate phosphatasePhospholipid-transporting ATPaseCation-transporting ATPaseHaloacid dehalogenase hydrolaseBifunctional polynucleotide phosphatase/kinasePhospholipid-transporting ATPaseHaloacid dehalogenase like hydrolase domain containing 5Sodium/potassium-transporting ATPase subunit alphaPhospholipid-transporting ATPaseMembrane-associated phosphatidylinositol transfer protein 3LD24878pPhospholipid-transporting ATPaseProbable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1NIF domain proteinHAD hydrolase familycopper-transporting ATPase 1 isoform X2NLI interacting factor-like phosphatase family proteinHaloacid dehalogenase like hydrolase domain containing 5haloacid dehalogenase-like hydrolase domain-containing protein 2Trehalose 6-phosphate phosphatasephosphoethanolamine/phosphocholine phosphatase isoform X2RNA polymerase II C-terminal domain phosphatase-like 3Trehalose 6-phosphate phosphataseAlpha,alpha-trehalose-phosphate synthase2,3-diketo-5-methylthio-1-phosphopentane phosphatase proteinTrehalose 6-phosphate phosphataseTrehalose 6-phosphate phosphataseBeta-phosphoglucomutasePhospholipid-transporting ATPaseCation-transporting ATPasePhospholipid-transporting ATPaseTrehalose-6-phosphate synthase 6CTD small phosphatase-like protein 2Putative haloacid dehalogenase-like hydrolasePhosphoserine phosphatase, chloroplasticCopper-exporting P-type ATPaseCytosolic purine 5-nucleotidaseBifunctional riboflavin kinase/FMN phosphataseMagnesium-dependent phosphatase 1Uncharacterized proteinTrehalose 6-phosphate phosphataseHAD-family hydrolase IIARNA polymerase II C-terminal domain phosphatase-like 4Cytosolic purine 5-nucleotidaseMagnesium-dependent phosphatase 1Calcium-transporting ATPaseCalcium-translocating P-type ATPase PMCA-typePhospholipid-transporting ATPaseHAD superfamily hydrolase, putativeHAD family hydrolase5'(3')-deoxyribonucleotidase, cytosolic typeGlycerol-3-phosphate 2-O-acyltransferase 6Glycerol-3-phosphate 2-O-acyltransferase 6Trehalose-6-phosphate phosphatase, putativeHydrolase family protein / HAD-superfamily proteinHAD-superfamily hydrolase, subfamily IIAMitochondrial import inner membrane translocase subunit TIM50Putative phospholipid-transporting ATPaseSimilar to FCP1-like phosphatasePhosphoserine phosphatase serbcopper-transporting ATPase 1 isoform X2HAD family hydrolaseH/K ATPase alpha subunit, putativeHaloacid dehalogenase superfamily proteinRelated to trehalose-6-phosphate phosphatasebifunctional TH2 protein, mitochondrialCopper-translocating P-type ATPasePhospholipid-transporting ATPasePhospholipid-transporting ATPaseTrehalose-6-phosphate synthase 10Putative magnesium dependent phosphatasePhosphoGlycolate Phosphatase HomologHAD phosphatase, family IIIAPhosphoserine phosphatase SerBTFIIF-stimulated CTD phosphataseTrehalose 6-phosphate phosphataseHAD-like proteinPyridoxal phosphate phosphataseHeavy metal translocating P-type ATPaseHAD superfamily phosphataseCytosolic 5-nucleotidaseSucrose-phosphate synthase 1D,D-heptose 1,7-bisphosphate phosphataseHaloacid dehalogenase-like hydrolase family protein4-nitrophenylphosphataseNuclear lim interactor-interacting factor,putativePhospholipid-transporting ATPaseMembrane-associated phosphatidylinositol transfer protein 2Phosphoenolpyruvate and 6-phosphogluconate phosphataseTrehalose 6-phosphate phosphatase5'-nucleotidase domain-containing protein, putativePutative Alpha,alpha-trehalose phosphate synthase subunit Tps3Hydrolase family protein / HAD-superfamily proteinUncharacterized protein, isoform BHAD family hydrolasePyrimidine nucleotidase, putativeUncharacterized proteinPhospholipid-transporting ATPaseCCC2p Cu(+2)-transporting P-type ATPaseUbiquitin-like domain containing CTD phosphatase 1Vegetative storage protein 1Phospholipid-transporting ATPaseCalcium-transporting ATPaseCTD small phosphatase-like proteinPlasma membrane calcium-transporting ATPase 2Mitochondrial import inner membrane translocase subunit TIM50HAD family hydrolase4-nitrophenylphosphatase, putativeBifunctional polynucleotide phosphatase/kinaseNuclear envelope morphologyNLI interacting factor-like phosphatase, putativePiso0_001792 proteinCation transporting P-ATPasePhospholipid-transporting ATPaseCopper-translocating P-type ATPaseATPase 2 plasma membrane-typeProbable sucrose-phosphatase 12,3-diketo-5-methylthio-1-phosphopentane phosphataseBifunctional polynucleotide phosphatase/kinaseGuanylyl cyclasePhospholipid-transporting ATPasePlasma membrane ATPaseHAD hydrolase, family IA, variant 34-nitrophenylphosphataseTrehalose 6-phosphate phosphataseP-type ATPase, putativeCopper-transporting ATPaseP-type cation-transporting ATPaseHaloacid dehalogenasePhospholipid-transporting ATPaseNLI interacting factor-like phosphatasePhospholipid-transporting ATPaseCation transporting ATPase, putativePredicted proteinNIF domain proteinNLI interacting factor-like phosphatasecopper-transporting ATPase 1 isoform X1Polynucleotide kinaseTrehalose-phosphataseHaloacid dehalogenase-like hydrolaseHaloacid dehalogenase-like hydrolaseHaloacid dehalogenase-like hydrolase (HAD) superfamily proteinPhosphoserine phosphatasePutative nuclear LIM factor interactor-interacting protein hyphal formBnaA03g18060D proteinHAD hydrolase, family IIID, variantHydrolase (HAD superfamily)alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1 isoform X3PhosphomannomutaseGlycerol-3-phosphate 2-O-acyltransferase 6Haloacid dehalogenase-like hydrolase4-nitrophenyl phosphataseBifunctional polynucleotide phosphatase/kinaseHAD family phosphataseHAD family phosphatasePhosphomannomutaseProbable cation-transporting ATPase HI_0290Phosphatidylglycerophosphatase GEP4, mitochondrialEnolase-phosphatase E1TIGR01456 family HAD hydrolasePhospholipid-transporting ATPaseProtein CBG02038PhosphomannomutaseHaloacid dehalogenase-like hydrolase (HAD) superfamily proteinYER134C-like proteinMagnesium dependent phosphatase 1Hydrolase, haloacid dehalogenase-like familyHAD family hydrolaseUnplaced genomic scaffold supercont1.6, whole genome shotgun sequenceTIGR01456 family HAD hydrolaseUncharacterized proteinCation-transporting ATPaseATPase 4 plasma membrane-typeRelated to alpha,alpha-trehalose-phosphate synthase, 115 KD subunitNuclear envelope-endoplasmic reticulum network proteinHaloacid dehalogenase-like hydrolaseGM16616Phosphatidyl synthaseUnplaced genomic scaffold supercont1.16, whole genome shotgun sequenceHAD superfamily hydrolaseBifunctional polynucleotide phosphatase/kinaseRNA polymerase II subunit A domain phosphatasePhospholipid-transporting ATPaseHAD-superfamily hydrolase, subfamily IIA containing proteinCopper-transporting ATPase PAA1 chloroplasticTFIIF-stimulated CTD phosphatase, putativePhosphoserine phosphataseNuclear LIM interactor-interacting factor 1Tpp1pNLI_interacting_factor-like_phosphatasePhospholipid-transporting ATPaseHAD family hydrolaseHaloacid_dehalogenase-like_hydrolase/HAD-hyrolase-likeglycerol-3-phosphate phosphataseHydrolase, haloacid dehalogenase-like familyHAD family hydrolaseAminophospholipid transporter, putativeCRE-FCP-1 proteinPhosphatidyl synthase, putativeTrehalose-phosphataseBnaAnng05460D proteinHaloacid dehalogenase like hydrolase domain containing 2Cation-transporting ATPasePutative cytosolic 5'-nucleotidase 3Potassium-transporting ATPase alpha chain 1Na+/K+ ATPase alpha subunit isoform 1Mitochondrial import inner membrane translocase subunit TIM50Phosphatase MT3486D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphataseHAD family phosphatasePolynucleotide kinase 3'-phosphatase, putativeGlycosyl hydrolase, putativeTrehalose-6-phosphate phosphatase OtsBTrehalose 6-phosphate phosphataseCation-transporting P-type ATPasePhospholipid-transporting ATPase IH-like proteinHaloacid dehalogenase-like hydrolaseTFIIF-stimulated CTD phosphatase, putativeHAD family hydrolaseNLI interacting factor-like phosphatase, putative5'-deoxynucleotidaseHaloacid dehalogenase family hydrolase domain containing proteinProbable hydrolase5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase, chloroplasticHAD-superfamily hydrolase, subfamily IA, variant 3Phosphoglycolate phosphatasePutative Alpha,alpha-trehalose-phosphate synthasep-nitrophenylphosphatase, putativeHaloacid dehalogenase-like hydrolase domain-containing proteinProbable sucrose-phosphate synthase 2BnaAnng05460D proteinCalcium-transporting ATPaseCopper-transporting ATPasePhospholipid-transporting ATPaseUnplaced genomic scaffold supercont1.8, whole genome shotgun sequenceCopper-transporting ATPase 22-deoxyglucose-6-phosphate phosphatase, putativeCopper-transporting P-type ATPaseAlpha,alpha-trehalose phosphate synthase subunit, putativePhosphomannomutaseInorganic pyrophosphatase 2Haloacid dehalogenase-like hydrolase (HAD) superfamily proteinRNA polymerase II ctd phosphatase, putativeHaloacid dehalogenase family hydrolase domain containing proteinPutative hydrolaseHaloacid dehalogenase/epoxide hydrolase family proteinProtein CBG09463Cat eye syndrome critical region proteinHaloacid dehalogenase family hydrolase, putativeHAD hydrolaseHAD hydrolaseHaloacid dehalogenase family hydrolase, putativeAcyl-CoA dehydrogenase family member 10Trehalose-6-phosphatase synthase S4Trehalose-phosphataseGM26347Putative P-type cation-transporting ATPasePhospholipid-transporting ATPasePhospholipid-transporting P-type ATPase, putativeUncharacterized proteinhaloacid dehalogenase-like hydrolase domain-containing 5Chromosome 9, whole genome shotgun sequenceTrehalose 6-phosphate phosphataseNLI interacting factor-like phosphatase family proteinNuclear LIM interactor-interacting factor 1LP01149pNuclear LIM interactor-interacting factor 1HAD-superfamily phosphatase, subfamily IIIC containing protein, expressedHaloacid dehalogenase family hydrolase domain containing proteinPutative Alpha,alpha-trehalose-phosphate synthase5'-nucleotidaseHaloacid dehalogenase-like hydrolase/HAD-hyrolase-like, putativeUncharacterized proteinPutative NipSnap protein K02D10.1Phospholipid-transporting ATPaseE1-E2 ATPase superfamily proteinphosphoserine phosphatase isoform X2Putative glycosyl hydrolaseHydrolase (HAD superfamily)Cation-transporting ATPaseHAD-IB family hydrolaseCTD small phosphatase-like protein isoform X3Phospholipid-transporting ATPase IA, putativePutative proton motive ATPasePhosphorylated carbohydrates phosphatase TM_1254Trehalose 6-phosphate phosphataseUncharacterized proteinMg-dependent acid phosphatasePredicted proteinUncharacterized proteinCTDNEP1 isoform 2Phosphoserine phosphatase (SerB)Nuclear LIM interactor-interacting factor 3, putativeNLI interacting factor family phosphataseWGS project CABT00000000 data, contig 2.7Haloacid dehalogenase family hydrolase domain containing proteinHAD family hydrolaseGH10306pGD12369PhosphotransferaseGD13364GM14093HAD-IIB family hydrolaseCopper-translocating P-type ATPaseCadmium, zinc and cobalt-transporting ATPaseUnplaced genomic scaffold supercont2.16, whole genome shotgun sequencePhospholysine phosphohistidine inorganic pyrophosphate phosphatase, putativeHAD superfamily hydrolase, putativeOs02g0790500 proteinTrehalose-6-phosphate synthaseUncharacterized protein5'-nucleotidaseHAD-superfamily hydrolase, subfamily IA, variant 3 containing proteinCytosolic IMP-GMP specific 5'-nucleotidasePhosphoserine phosphatase SerBHAD superfamily, subfamily IIIB acid phosphataseBifunctional epoxide hydrolase 2Haloacid dehalogenaseD,D-heptose 1,7-bisphosphate phosphataseHaloacid dehalogenase-like hydrolase family proteinHAD family hydrolaseHAD superfamily hydrolaseHAD family phosphataseTrehalose-6-phosphate synthaseTrehalose 6-phosphate phosphataseGD13364Haloacid dehalogenase family hydrolaseAminophospholipid transporter, putative4-nitrophenylphosphatase, putativeUncharacterized proteinPolynucleotide kinase 3'-phosphatasePlasma membrane Ca2+ ATPase isoform 2Uncharacterized proteinUncharacterized protein, isoform AHeavy metal translocating P-type ATPasePhospholipid-transporting ATPasePhospholipid-transporting ATPasePhosphotransferaseTrehalose 6-phosphate phosphatase RA3Phospholipid-transporting ATPaseHAD-superfamily hydrolase, subfamily IIA containing proteinTrehalose-6-phosphate synthaseAGL041CpPhospholipid-transporting ATPaseCopper-transporting ATPase PAA1 chloroplasticPhospholipid-transporting ATPasePredicted proteinUPF0655 protein C17G9.12cHaloacid dehalogenase-like hydrolase domain-containing 5Uncharacterized proteinUncharacterized proteinUncharacterized proteinPhosphoserine phosphatase (SerB)Uncharacterized proteinAT02326pNLI_interacting_factor-like_phosphatase_-_putativeD,D-heptose 1,7-bisphosphate phosphataseMannosylfructose-phosphate phosphataseUncharacterized proteinGH05933pPhospholipid-transporting ATPase IA, putativebifunctional polynucleotide phosphatase/kinaseAlpha,alpha-trehalose-phosphate synthasePhospholipid-transporting ATPaseGlycerol-3-phosphate dehydrogenase [NAD(+)]Cleavage and polyadenylation factor 6-related proteinUncharacterized proteinPhospholipid-transporting ATPase IA, putativePhospholipid-transporting ATPase-like proteinPhospholipid-transporting ATPaseCalcium transporting rt-atpaseGlucosyl-3-phosphoglycerate/mannosyl-3-phosphoglycerate phosphataseCalcium-transporting ATPaseCation-transporting ATPase (P-type)Uncharacterized protein
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FunFam 253: TIGR01456 family HAD hydrolase

GO Diversity

Unique GO annotations
Created with Highcharts 3.0.5
0 Unique GO terms

EC Diversity

Unique EC annotations
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0 Unique EC terms

Species Diversity

Unique species annotations
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11 Unique species

Statistics

Members
CATH Domains: 0
Sequences: 13
Annotations
Unique GO:
Unique EC: 0
Unique Species: 11
Representative
Rep ID: D0NKK6/23-90_256-332
Inherited Annotations: 0
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