The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"HAD superfamily/HAD-like
".
FunFam 246: Bifunctional polynucleotide phosphatase/kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Damaged DNA binding GO:0003684
Interacting selectively and non-covalently with damaged DNA.
|
10 | Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) |
|
Polynucleotide 3'-phosphatase activity GO:0046403
Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.
|
10 | Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) Q8ID74 (/IDA) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
10 | Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) Q8ID74 (/ISS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
