The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 102: Enolase-phosphatase E1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acireductone synthase activity GO:0043874
Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
6 Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA)
Acireductone synthase activity GO:0043874
Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
6 Q0VD27 (/ISS) Q28C69 (/ISS) Q5PPH0 (/ISS) Q6GMI7 (/ISS) Q6GMI7 (/ISS) Q8BGB7 (/ISS)
Acireductone synthase activity GO:0043874
Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
1 Q8BGB7 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-methionine salvage from methylthioadenosine GO:0019509
The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
6 Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA) Q9UHY7 (/IDA)
L-methionine salvage from methylthioadenosine GO:0019509
The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
6 Q0VD27 (/ISS) Q28C69 (/ISS) Q5PPH0 (/ISS) Q6GMI7 (/ISS) Q6GMI7 (/ISS) Q8BGB7 (/ISS)
L-methionine salvage from methylthioadenosine GO:0019509
The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
6 Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS)
L-methionine salvage from methylthioadenosine GO:0019509
The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
1 Q8BGB7 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS) Q9UHY7 (/TAS)
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