The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"PAS domain
".
FunFam 35: Aryl hydrocarbon receptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 52 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
E-box binding GO:0070888
Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
|
12 |
O02747 (/ISS)
P35869 (/ISS)
P35869 (/ISS)
P41738 (/ISS)
P41738 (/ISS)
Q8R4S2 (/ISS)
Q8R4S4 (/ISS)
Q8R4S5 (/ISS)
Q8R4S6 (/ISS)
Q8R4S7 (/ISS)
(2 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
11 |
B3DJJ7 (/IDA)
B3DK40 (/IDA)
P30561 (/IDA)
Q1LV27 (/IDA)
Q4U3K9 (/IDA)
Q8R4S2 (/IDA)
Q8R4S4 (/IDA)
Q8R4S5 (/IDA)
Q8R4S6 (/IDA)
Q8R4S7 (/IDA)
(1 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
O44712 (/IPI)
P30561 (/IPI)
P35869 (/IPI)
P35869 (/IPI)
P41738 (/IPI)
P41738 (/IPI)
Q8R4S2 (/IPI)
Q8R4S4 (/IPI)
Q8R4S5 (/IPI)
Q8R4S6 (/IPI)
(1 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
10 | O02747 (/ISS) P35869 (/ISS) P35869 (/ISS) P41738 (/ISS) P41738 (/ISS) Q8R4S2 (/ISS) Q8R4S4 (/ISS) Q8R4S5 (/ISS) Q8R4S6 (/ISS) Q8R4S7 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
9 | O44712 (/IDA) P30561 (/IDA) P35869 (/IDA) P35869 (/IDA) Q8R4S2 (/IDA) Q8R4S4 (/IDA) Q8R4S5 (/IDA) Q8R4S6 (/IDA) Q8R4S7 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
8 | P30561 (/IDA) P35869 (/IDA) P35869 (/IDA) Q8R4S2 (/IDA) Q8R4S4 (/IDA) Q8R4S5 (/IDA) Q8R4S6 (/IDA) Q8R4S7 (/IDA) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
8 | B3DK40 (/IDA) P30561 (/IDA) P35869 (/IDA) P35869 (/IDA) P41738 (/IDA) P41738 (/IDA) Q1LV27 (/IDA) Q9YGV3 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
8 | O02747 (/ISS) P41738 (/ISS) P41738 (/ISS) Q8R4S2 (/ISS) Q8R4S4 (/ISS) Q8R4S5 (/ISS) Q8R4S6 (/ISS) Q8R4S7 (/ISS) |
|
Sequence-specific double-stranded DNA binding GO:1990837
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
|
8 | O02747 (/ISS) P41738 (/ISS) P41738 (/ISS) Q8R4S2 (/ISS) Q8R4S4 (/ISS) Q8R4S5 (/ISS) Q8R4S6 (/ISS) Q8R4S7 (/ISS) |
|
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
Showing 1 to 10 of 52 entries
There are 109 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
28 |
A0A087R7E6 (/ISS)
A0A087VRV7 (/ISS)
A0A091FPM1 (/ISS)
A0A091J332 (/ISS)
A0A091KHE5 (/ISS)
A0A091PPN0 (/ISS)
A0A091QGK9 (/ISS)
A0A091VSG9 (/ISS)
A0A093P2Q9 (/ISS)
D7REZ1 (/ISS)
(18 more) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
28 |
A0A087R7E6 (/ISS)
A0A087VRV7 (/ISS)
A0A091FPM1 (/ISS)
A0A091J332 (/ISS)
A0A091KHE5 (/ISS)
A0A091PPN0 (/ISS)
A0A091QGK9 (/ISS)
A0A091VSG9 (/ISS)
A0A093P2Q9 (/ISS)
D7REZ1 (/ISS)
(18 more) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
23 |
A0A087R7E6 (/ISS)
A0A087VRV7 (/ISS)
A0A091FPM1 (/ISS)
A0A091J332 (/ISS)
A0A091KHE5 (/ISS)
A0A091PPN0 (/ISS)
A0A091QGK9 (/ISS)
A0A091VSG9 (/ISS)
A0A093P2Q9 (/ISS)
D7REZ1 (/ISS)
(13 more) |
|
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
12 |
B3DK40 (/IDA)
F1NLX8 (/IDA)
O44712 (/IDA)
P30561 (/IDA)
P35869 (/IDA)
P35869 (/IDA)
P41738 (/IDA)
P41738 (/IDA)
Q1LV27 (/IDA)
Q9I9E2 (/IDA)
(2 more) |
|
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
|
12 |
O02747 (/ISS)
P35869 (/ISS)
P35869 (/ISS)
P41738 (/ISS)
P41738 (/ISS)
Q8R4S2 (/ISS)
Q8R4S4 (/ISS)
Q8R4S5 (/ISS)
Q8R4S6 (/ISS)
Q8R4S7 (/ISS)
(2 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
12 |
O02747 (/ISS)
P35869 (/ISS)
P35869 (/ISS)
P41738 (/ISS)
P41738 (/ISS)
Q8R4S2 (/ISS)
Q8R4S4 (/ISS)
Q8R4S5 (/ISS)
Q8R4S6 (/ISS)
Q8R4S7 (/ISS)
(2 more) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
9 | F1NLX8 (/IDA) P30561 (/IDA) Q8R4S2 (/IDA) Q8R4S4 (/IDA) Q8R4S5 (/IDA) Q8R4S6 (/IDA) Q8R4S7 (/IDA) Q9I9E2 (/IDA) Q9PTI7 (/IDA) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
8 | P30561 (/TAS) P35869 (/TAS) P35869 (/TAS) Q8R4S2 (/TAS) Q8R4S4 (/TAS) Q8R4S5 (/TAS) Q8R4S6 (/TAS) Q8R4S7 (/TAS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
6 | P30561 (/IDA) Q8R4S2 (/IDA) Q8R4S4 (/IDA) Q8R4S5 (/IDA) Q8R4S6 (/IDA) Q8R4S7 (/IDA) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
Showing 1 to 10 of 109 entries
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
31 |
A0A087R7E6 (/ISS)
A0A087VRV7 (/ISS)
A0A091FPM1 (/ISS)
A0A091J332 (/ISS)
A0A091KHE5 (/ISS)
A0A091PPN0 (/ISS)
A0A091QGK9 (/ISS)
A0A091VSG9 (/ISS)
A0A093P2Q9 (/ISS)
D7REZ1 (/ISS)
(21 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
24 |
A0A087R7E6 (/ISS)
A0A087VRV7 (/ISS)
A0A091FPM1 (/ISS)
A0A091J332 (/ISS)
A0A091KHE5 (/ISS)
A0A091PPN0 (/ISS)
A0A091QGK9 (/ISS)
A0A091VSG9 (/ISS)
A0A093P2Q9 (/ISS)
D7REZ1 (/ISS)
(14 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
14 |
B3DK40 (/IDA)
F1NLX8 (/IDA)
P30561 (/IDA)
P35869 (/IDA)
P35869 (/IDA)
Q1LV27 (/IDA)
Q8R4S2 (/IDA)
Q8R4S4 (/IDA)
Q8R4S5 (/IDA)
Q8R4S6 (/IDA)
(4 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
B3DK40 (/IDA)
F1NLX8 (/IDA)
P30561 (/IDA)
P35869 (/IDA)
P35869 (/IDA)
P41738 (/IDA)
P41738 (/IDA)
Q1LV27 (/IDA)
Q9I9E2 (/IDA)
Q9PTI7 (/IDA)
(1 more) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
8 | P30561 (/TAS) P35869 (/TAS) P35869 (/TAS) Q8R4S2 (/TAS) Q8R4S4 (/TAS) Q8R4S5 (/TAS) Q8R4S6 (/TAS) Q8R4S7 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
6 | P30561 (/ISO) Q8R4S2 (/ISO) Q8R4S4 (/ISO) Q8R4S5 (/ISO) Q8R4S6 (/ISO) Q8R4S7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P30561 (/IDA) P35869 (/IDA) P35869 (/IDA) P41738 (/IDA) P41738 (/IDA) |
Showing 1 to 10 of 19 entries
