CATH Superfamily 3.30.450.20

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Potassium voltage-gated channel subfamily H member 7	748	3D	4hqaA00	-	97.9
2	LOV domain-containing protein	639	3D	5hziB02	-	74.0
4	Period circadian protein homolog 3	549	3D	3gdiB02	-	85.3
3	Aryl hydrocarbon receptor nuclear translocator 2	541		-	-	69.6
5	Hypoxia-inducible factor 1 subunit alpha	523		-	-	91.6
6	aryl hydrocarbon receptor nuclear translocator-like protein 1	502	3D	4f3lB02	-	75.2
7	Nuclear receptor coactivator	487		-	-	91.4
9	Potassium voltage-gated channel subfamily H member 1	475	3D	4lloH00	-	93.5
8	Nuclear receptor coactivator	473		-	-	90.0
10	Aryl hydrocarbon receptor nuclear translocator-like, isoform CRA_b	433	3D	4f3lB03	-	72.3
11	Hybrid signal transduction histidine kinase	415		-	-	70.3
15	Hypoxia-inducible factor 1-alpha isoform 1	413	3D	4h6jA00	-	92.6
12	Calcium channel, voltage-dependent, alpha2/delta subunit 3	408		-	-	92.5
13	Period circadian protein homolog 2	407	3D	3gdiB01	-	92.5
14	voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1	392		-	-	76.7
16	Circadian locomoter output cycles protein	334	3D	4f3lA03	-	65.1
17	SIM bHLH transcription factor 2	328		-	-	72.2
18	Sensor histidine kinase DcuS	323	3D	2w0nA00	-	96.5
19	Aryl hydrocarbon receptor 1	304		-	-	82.4
20	Aryl hydrocarbon receptor nuclear translocator 2	301		-	-	62.5
21	Neuronal PAS domain-containing protein 3	284		-	-	95.6
22	circadian locomoter output cycles protein kaput	278	3D	4f3lA02	-	79.1
23	Phosphodiesterase	261		-	-	72.1
28	Aryl hydrocarbon receptor nuclear translocator 1	230	3D	5ufpB01	-	63.3
24	VWFA and cache domain-containing protein 1	223		-	-	96.4
25	Neuronal PAS domain protein 3 isoform 1	220		-	-	76.6
26	single-minded homolog 1	212		-	-	57.7
27	Nuclear receptor coactivator 3	206		-	-	78.1
29	VWFA and cache domain-containing protein 1	201		-	-	89.4
31	Nuclear receptor coactivator	181	3D	5y7wB00	-	54.3
30	Phytochrome	180		-	-	93.6
32	Aerobic respiration control sensor protein	169		-	-	43.0
33	Nitrogen regulation protein NR II	168		-	-	14.7
36	Putative LOV domain-containing protein	159	3D	2z6cB00	-	79.4
35	Aryl hydrocarbon receptor	159	3D	4m4xB00	-	92.1
34	Phytochrome	158		-	-	95.4
37	Cell wall metabolism sensor histidine kinase	148	3D	4mn6B00	-	84.7
38	Sensor domain-containing diguanylate cyclase	143		-	-	57.1
41	Adagio protein 1	142	3D	5svwD00	-	83.8
39	Phytochrome	142		-	-	92.3
40	Phosphodiesterase	139		-	-	77.1
42	hypoxia-inducible factor 3-alpha isoform X1	127	3D	4wn5B00	-	80.6
43	DNA-binding transcriptional regulator TyrR	122	3D	2jheD02	-	0.0
48	Methyl-accepting chemotaxis protein	119	3D	6iouB02	-	98.4
45	Sensor histidine kinase DcuS	116	3D	3by8A00	-	92.6
44	Phosphate regulon sensor histidine kinase PhoR	115		-	-	68.9
46	Aerotaxis sensor receptor	108		-	-	89.4
47	SIM bHLH transcription factor 2	104		-	-	78.3
60	Sensor protein FixL	100	3D	2vv8D00	-	98.3
49	Sensor histidine kinase DpiB	93		-	-	19.0
50	PAS domain-containing sensor histidine kinase	85		-	-	25.0
64	Vivid PAS protein VVD	84	3D	3d72B00	-	88.0
51	Cell wall metabolism sensor histidine kinase	83		-	-	7.2
52	Sigma-54 dependent transcriptional regulator	82		-	-	46.9
53	Sensor histidine kinase/response regulator	75		-	-	84.4
54	Trachealess, isoform D	74		-	-	79.8
55	neuronal PAS domain-containing protein 4	73		-	-	74.5
56	aryl hydrocarbon receptor repressor	71		-	-	68.6
57	Voltage-dependent calcium channel subunit alpha-2/delta-4	69		-	-	87.2
58	neuronal PAS domain-containing protein 4	68		-	-	25.5
59	PAS domain containing serine/threonine kinase	66	3D	1ll8A00	-	98.2
61	Histidine kinase 5	62		-	-	75.4
66	Period circadian protein	62	3D	3rtyH02	-	81.4
72	Period circadian protein	57	3D	3rtyH01	-	84.1
62	Diguanylate cyclase GGDEF	56		-	-	80.2
63	White collar 1 protein	54		-	-	74.6
65	probable G-protein coupled receptor 158	53		-	-	35.0
67	PAS domain S-box protein	49		-	-	44.3
68	Methyl-accepting chemotaxis protein	49		-	-	82.6
69	Aryl hydrocarbon receptor	49		-	-	80.8
70	Two-component system sensor histidine kinase CreC	48		-	-	26.1
71	PAS domain-containing sensor histidine kinase	48		-	-	44.6
75	Methyl-accepting chemotaxis protein	48	3D	4hi4G00	-	89.7
74	Aryl hydrocarbon receptor	44		-	-	81.7
73	Putative Sensor histidine kinase	44		-	-	77.2
76	Phosphate regulon sensor histidine kinase PhoR	42		-	-	40.1
77	Hybrid signal transduction histidine kinase	41		-	-	67.2
78	Sensor histidine kinase	40		-	-	49.8
79	NADPH-dependent FMN reductase	40		-	-	28.7
437	Photoactive yellow protein	40	3D	6mhnA00	-	9.9
81	Dysfusion, isoform B	39		-	-	93.4
80	protein TWIN LOV 1	39		-	-	75.9
82	sigma-54-dependent Fis family transcriptional regulator	38		-	-	70.3
83	Cyclic di-GMP phosphodiesterase Gmr	38		-	-	3.1
84	Sensor histidine kinase CitA	37	3D	2v9aB00	-	14.4
85	PAS domain-containing protein tyrosine kinase family protein	35		-	-	70.7
87	White collar 1 protein	33		-	-	76.5
86	PAS domain-containing sensor histidine kinase	33		-	-	22.2
135	Ptaureo1a lov2 domain	33	3D	5dklB00	-	77.9
88	Sensory transduction histidine kinase	31		-	-	100.0
90	Uncharacterized protein, isoform B	30		-	-	77.4
89	Trachealess, isoform E	30		-	-	63.6
91	Neuronal PAS domain-containing protein 3	29		-	-	33.1
92	Related to white collar 1 protein	28		-	-	73.6
93	Histidine kinase A two component receptor	28		-	-	20.7
94	Single-minded, isoform C	27		-	-	46.3
96	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8	27		-	-	67.9
97	Aryl hydrocarbon receptor repressor	27		-	-	65.6
95	Sigma-54-dependent transcriptional regulator ygeV	27		-	-	6.5
98	Sensor histidine kinase ResE	26		-	-	76.0
169	Bacteriophytochrome protein	26	3D	5c5kD02	-	92.2
99	Sensory box sensor histidine kinase	25		-	-	98.2
100	Protein TWIN LOV 1	23		-	-	67.0
101	Similar, isoform B	23		-	-	90.6
103	Methyl-accepting chemotaxis protein	22		-	-	76.6
102	Sensor protein kinase WalK	22		-	-	0.0
104	Sensor histidine kinase/response regulator	22		-	-	28.9
106	Potassium voltage-gated channel subfamily H member 1	21		-	-	11.9
105	Uncharacterized protein, isoform A	21		-	-	58.9
107	PAS domain-containing sensor histidine kinase	21		-	-	14.0
109	Sensor domain-containing diguanylate cyclase	20		-	-	2.1
108	Methyl-accepting chemotaxis protein signaling domain protein	20		-	-	75.6
111	Potassium voltage-gated channel subfamily H member 5	19		-	-	15.3
170	Oxygen sensor protein DosP	19	3D	1vb6B00	-	19.2
148	PTS-dependent dihydroxyacetone kinase operon regulatory protein	19	3D	4lrzH02	-	3.4
110	Signal transduction histidine-protein kinase atoS	19		-	-	0.0
112	Taiman, isoform C	17		-	-	51.3
114	Hypoxia inducible factor 1 subunit alpha, like	17		-	-	76.6
113	Taiman, isoform C	17		-	-	3.7
155	Sensor histidine kinase TodS	17	3D	5hwwB00	-	96.7
115	potassium voltage-gated channel subfamily H member 3 isoform X2	17		-	-	68.2
116	period circadian protein homolog 3 isoform X2	17		-	-	45.8
127	C4-dicarboxylate transport sensor protein	16	3D	3by9B02	-	68.4
118	Potassium voltage-gated channel subfamily H member 8	16		-	-	70.5
117	Uncharacterized protein, isoform A	16		-	-	52.1
119	Serine threonine protein kinase	16		-	-	61.0
120	PAS domain S-box protein	16		-	-	97.3
122	PAS domain-containing sensor histidine kinase	15		-	-	32.0
123	Dysfusion, isoform B	15		-	-	38.6
121	Uncharacterized protein, isoform B	15		-	-	25.2
124	uncharacterized protein LOC108093306	14		-	-	17.6
125	Histidine kinase	14		-	-	0.7
126	Putative diguanylate cyclase YegE	14		-	-	11.1
128	PAS domain S-box protein	13		-	-	18.0
134	Fis family transcriptional regulator	13		-	-	0.0
132	Methyl-accepting chemotaxis protein PctA	13		-	-	94.2
131	Sensor histidine kinase	13		-	-	10.1
133	Methyl-accepting chemotaxis protein signaling domain protein	13		-	-	0.0
129	Uncharacterized protein	13		-	-	90.8
130	Period protein homolog lin-42	13		-	-	13.5
136	Sensor histidine kinase/response regulator Fos-1	13		-	-	63.8
138	VWFA and cache domain-containing protein CG16868	12		-	-	51.7
137	Two-component sensor histidine kinase	12		-	-	0.0
140	Cyclic-di-AMP phosphodiesterase	12		-	-	3.5
141	Similar, isoform D	12		-	-	43.4
143	Unplaced genomic scaffold supercont2.18, whole genome shotgun sequence	12		-	-	9.4
139	Cyclic-di-AMP phosphodiesterase	12		-	-	3.2
142	PAS domain-containing protein	12		-	-	16.6
144	Nuclear receptor coactivator 2	12		-	-	81.6
146	PAS domain S-box protein	11		-	-	23.7
157	Methyl-accepting chemotaxis protein	11		-	-	43.2
152	Phosphodiesterase	11		-	-	10.4
154	Probable diguanylate cyclase DgcE	11		-	-	77.2
153	Protein TWIN LOV 1 isoform D	11		-	-	67.8
151	Sensor histidine kinase LuxQ	11		-	-	44.6
145	AGAP009664-PA	11		-	-	20.0
149	Peroxide stress-activated histidine kinase mak1	11		-	-	72.5
156	Two-component sensor histidine kinase	11		-	-	92.6
150	PAS domain-containing sensor histidine kinase	11		-	-	36.2
147	Antitoxin of toxin-antitoxin system	11		-	-	2.5
197	Probable sensor histidine kinase pdtaS	11	3D	2ykhB02	-	0.0
165	Unplaced genomic scaffold supercont2.2, whole genome shotgun sequence	10		-	-	18.4
158	Circadian locomoter output cycles protein kaput	10		-	-	13.1
166	CMGC/MAPK protein kinase	10		-	-	9.5
160	PAS domain containing repressor 1	10		-	-	19.8
167	Sensory box/GGDEF family protein	10		-	-	14.3
168	Two-component sensor histidine kinase	10		-	-	87.5
162	Methyl-accepting chemotaxis protein	10		-	-	9.1
159	Alkaline phosphatase synthesis sensor protein PhoR	10		-	-	5.8
164	Sensor histidine kinase	10		-	-	7.8
163	Sensor histidine kinase	10		-	-	11.0
161	Cyclic-di-AMP phosphodiesterase	10		-	-	0.0
171	Protein CBR-AHA-1	9		-	-	26.6
180	Phosphoglycerate kinase	9		-	-	13.1
173	Putative LOV domain-containing protein	9		-	-	29.0
186	Unplaced genomic scaffold supercont2.18, whole genome shotgun sequence	9		-	-	82.8
185	Sensory transduction histidine kinase	9		-	-	96.5
178	Methyl-accepting chemotaxis protein	9		-	-	0.0
177	Methyl-accepting chemotaxis protein	9		-	-	0.0
172	Cyclic di-GMP phosphodiesterase Gmr	9		-	-	15.2
174	BHLH-PAS factor	9		-	-	10.1
176	Serine/threonine phosphatase containing a PAS domain	9		-	-	8.8
183	Methyl-accepting chemotaxis protein	9		-	-	0.8
181	Probable diguanylate cyclase DgcE	9		-	-	5.6
187	Hypoxia-inducible factor 1-alpha	9		-	-	79.7
175	Hypoxia-inducible factor 1	9		-	-	13.6
184	Hybrid sensor histidine kinase/response regulator	9		-	-	37.9
179	PAS domain-containing sensor histidine kinase	9		-	-	37.5
182	Magnesium or manganese-dependent protein phosphatase	9		-	-	23.6
209	DNA-binding protein	8		-	-	58.3
211	Protein TWIN LOV 1	8		-	-	47.7
213	VWFA and cache domain-containing protein	8		-	-	71.1
190	Histidine kinase sensor protein	8		-	-	4.1
205	Hypoxia-inducible factor 1	8		-	-	17.5
196	Predicted protein	8		-	-	84.1
199	Sensor histidine kinase	8		-	-	0.0
189	AGAP000773-PA	8		-	-	36.9
195	Cell wall metabolism sensor histidine kinase WalK	8		-	-	0.0
200	Sensor histidine kinase KinD	8		-	-	12.2
214	Hypoxia-inducible factor 1-alpha	8		-	-	30.0
206	PAS domain-containing serine/threonine-protein kinase	8		-	-	3.3
212	Diguanylate cyclase	8		-	-	47.2
210	Sensory box/GGDEF family protein	8		-	-	7.7
204	Protein FimX	8		-	-	0.0
202	Voltage-dependent calcium channel unc-36	8		-	-	7.7
208	Periplasmic [Fe] hydrogenase	8		-	-	48.3
207	Protein kinase	8		-	-	10.5
193	Transcriptional regulator, LuxR family	8		-	-	9.8
191	Two-component system sensor	8		-	-	0.0
194	Cell wall metabolism sensor histidine kinase WalK	8		-	-	2.9
188	Heme-regulated cyclic AMP phosphodiesterase Direct oxygen sensor protein	8		-	-	1.0
192	Sensory box sensor histidine kinase	8		-	-	5.5
198	Two-component system, cell cycle sensor histidine kinase PleC	8		-	-	15.2
201	Cyclic-di-AMP phosphodiesterase	8		-	-	0.0
203	Histidine kinase response regulator hybrid protein	8		-	-	0.0
231	PAS domain-containing sensor histidine kinase	7		-	-	83.3
223	neuronal PAS domain-containing protein 3 isoform X3	7		-	-	13.0
221	Sensor kinase CitA	7		-	-	0.0
227	AGC protein kinase, variant	7		-	-	7.1
218	Sensor kinase citA	7		-	-	7.4
228	Histidine kinase	7		-	-	13.4
217	Sensor histidine kinase	7		-	-	3.3
224	Methyl-accepting chemotaxis protein	7		-	-	0.0
222	Protein CBR-TAG-180	7		-	-	15.0
220	Sensory box/GGDEF family protein	7		-	-	8.3
216	Sensory box/GGDEF family protein	7		-	-	10.7
230	Methyl-accepting chemotaxis protein	7		-	-	0.0
226	Sensory transduction histidine kinase	7		-	-	51.6
225	Methyl-accepting chemotaxis protein	7		-	-	0.0
215	Sensory box/GGDEF family protein	7		-	-	7.9
229	Methyl-accepting chemotaxis sensory transducer	7		-	-	36.5
219	Nitrogen regulation protein	7		-	-	0.0
233	PAS domain S-box protein	6		-	-	0.0
245	C4-dicarboxylate transport sensor protein	6		-	-	8.9
260	Putative Sigma factor regulatory protein	6		-	-	0.0
253	Phytochrome-like protein	6		-	-	10.6
266	Voltage-dependent calcium channel subunit alpha-2/delta-1	6		-	-	79.7
251	Sensory box sensor histidine kinase/response regulator VieS	6		-	-	14.0
249	Serine phosphatase RsbU Regulator of sigma subunit	6		-	-	4.1
257	Similar to serine threonine protein kinase	6		-	-	9.1
265	Methyl-accepting chemotaxis protein	6		-	-	0.7
240	Sensory box/GGDEF family protein	6		-	-	0.0
258	SIM bHLH transcription factor 2	6		-	-	8.6
246	Two-component sensor kinase citS	6		-	-	15.2
238	Uncharacterized protein	6		-	-	14.4
237	Integral membrane sensor protein	6		-	-	4.3
254	Sensory box sensor histidine kinase/response regulator	6		-	-	1.0
232	Diguanylate cyclase	6		-	-	17.9
252	PAS sensor protein	6		-	-	11.9
234	PAS domain S-box protein	6		-	-	0.0
236	Histidine kinase	6		-	-	0.0
248	Phosphoserine phosphatase RsbP	6		-	-	0.0
250	Methyl-accepting chemotaxis protein	6		-	-	0.0
325	Period circadian protein homolog 1	6	3D	4dj2D01	-	19.6
247	Aryl hydrocarbon receptor protein 1	6		-	-	14.5
263	Methyl-accepting chemotaxis protein	6		-	-	1.5
261	Diguanylate cyclase	6		-	-	15.9
256	Hypothetical regulatory protein	6		-	-	13.5
244	Sensor histidine kinase	6		-	-	0.0
242	Cyclic di-GMP phosphodiesterase Gmr	6		-	-	1.5
255	Sensory transduction histidine kinase	6		-	-	15.2
267	Voltage-dependent calcium channel subunit alpha-2/delta-1	6		-	-	79.6
268	Uncharacterized protein	6		-	-	88.4
241	Uncharacterized protein	6		-	-	75.6
235	Signal transduction histidine kinase	6		-	-	0.0
243	Cyclic di-GMP phosphodiesterase Gmr	6		-	-	0.0
259	Phytochrome-like protein	6		-	-	4.2
264	Methyl-accepting chemotaxis protein	6		-	-	7.1
262	Methyl-accepting chemotaxis sensory transducer	6		-	-	40.7
239	Sensory box/GGDEF family protein	6		-	-	0.0
278	PAS domain-containing sensor histidine kinase	5		-	-	0.0
277	Two-component sensor histidine kinase	5		-	-	0.0
299	Methyl-accepting chemotaxis protein	5		-	-	0.0
285	Methyl-accepting chemotaxis protein	5		-	-	0.0
300	Methyl-accepting chemotaxis protein	5		-	-	6.2
274	Cyclic di-GMP phosphodiesterase Gmr	5		-	-	0.0
289	Sensory box histidine kinase/response regulator	5		-	-	11.2
272	Sensor histidine kinase RcsC	5		-	-	1.0
295	GGDEF family protein	5		-	-	40.9
286	Methyl-accepting chemotaxis protein	5		-	-	0.0
271	Sensor histidine kinase RcsC	5		-	-	1.0
280	Sensor histidine kinase KinD	5		-	-	5.5
273	Uncharacterized protein	5		-	-	30.7
269	Two-component sensor kinase	5		-	-	10.2
296	Diguanylate cyclase GGDEF	5		-	-	8.3
290	Development and carotenogenesis control-1 protein	5		-	-	7.3
292	Response regulator	5		-	-	8.0
275	C4-dicarboxylate transport sensor protein	5		-	-	0.0
294	GGDEF domain-containing protein	5		-	-	6.0
287	Transcriptional regulator TyrR	5		-	-	0.0
335	Transcriptional regulator, PpsR	5	3D	4l9eA00	-	7.4
288	Development and carotenogenesis control-1 protein	5		-	-	4.5
279	Two-component sensor histidine kinase	5		-	-	0.0
282	Neuronal PAS domain protein 4a	5		-	-	25.9
297	Diguanylate cyclase GGDEF	5		-	-	7.5
284	Helix-loop-helix 34	5		-	-	14.1
303	Sensory transduction histidine kinase	5		-	-	86.9
298	Methyl-accepting chemotaxis protein	5		-	-	0.0
301	SIM bHLH transcription factor 2	5		-	-	38.6
304	Probable serine/threonine-protein kinase DDB_G0280133	5		-	-	82.2
270	Sensor histidine kinase RcsC	5		-	-	0.0
283	Helix-loop-helix 34	5		-	-	18.0
281	Cyclic-di-AMP phosphodiesterase	5		-	-	2.8
276	Sensor histidine kinase	5		-	-	21.1
302	Sensory transduction histidine kinase	5		-	-	51.6
293	Histidine kinase	5		-	-	0.0
291	Histidine kinase	5		-	-	77.6
317	Methyl-accepting chemotaxis protein	4		-	-	8.3
328	Accessory colonization factor AcfB	4		-	-	0.0
340	Potassium voltage-gated channel, subfamily H eag-related	4		-	-	70.8
318	Hypoxia-inducible factor 1 subunit alpha,-like	4		-	-	3.1
327	Methyl-accepting chemotaxis protein	4		-	-	0.0
337	Methyl-accepting chemotaxis protein	4		-	-	0.0
338	Protein kinase, putative	4		-	-	7.2
346	Sensor histidine kinase	4		-	-	76.6
314	Two-component hybrid sensor and regulator	4		-	-	2.8
332	Sensory transduction histidine kinase	4		-	-	68.1
324	Two-component sensor histidine kinase	4		-	-	0.0
334	PAS domain-containing sensor histidine kinase	4		-	-	0.0
322	Sensory box histidine kinase	4		-	-	1.6
312	Nitrogen fixation regulatory protein, NifL	4		-	-	5.5
306	GGDEF family protein	4		-	-	0.0
309	Hybrid sensor histidine kinase/response regulator	4		-	-	17.8
333	Methyl-accepting chemotaxis protein	4		-	-	0.0
345	Uncharacterized protein	4		-	-	64.0
331	Hybrid signal transduction histidine	4		-	-	21.6
321	Methyl-accepting chemotaxis protein	4		-	-	0.0
313	Probable two-component sensor	4		-	-	0.0
323	Sensory box histidine kinase	4		-	-	1.0
311	Nitrogen fixation regulatory protein, NifL	4		-	-	6.2
305	GGDEF family protein	4		-	-	0.0
315	Sensor histidine kinase HpkA	4		-	-	1.0
343	Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing	4		-	-	77.1
341	Nuclear receptor coactivator 3	4		-	-	71.3
319	Hypoxia-inducible factor 1 subunit alpha,-like	4		-	-	3.2
329	Sensory box histidine kinase/response regulator	4		-	-	0.0
339	Methyl-accepting chemotaxis transmembrane protein	4		-	-	1.1
347	PAS sensor protein	4		-	-	79.8
320	Methyl-accepting chemotaxis protein	4		-	-	0.0
310	Two-component system histidine kinase, FrrD	4		-	-	9.4
348	Two component system histidine kinase	4		-	-	82.6
336	Protein_kinase_-_putative	4		-	-	11.5
326	Hybrid sensor histidine kinase/response regulator	4		-	-	5.5
330	Sensory transduction histidine kinase	4		-	-	23.4
316	Methyl-accepting chemotaxis protein	4		-	-	6.9
307	Sporulation-specific ATP-dependent proteinhistidine kinase	4		-	-	0.0
344	Uncharacterized protein	4		-	-	74.1
308	Sporulation-specific ATP-dependent proteinhistidine kinase	4		-	-	0.0
342	Hybrid sensor histidine kinase/response regulator	4		-	-	73.6
386	Transcriptional regulator, PpsR	3		-	-	0.0
358	Two-component hybrid sensor and regulator	3		-	-	5.8
365	Predicted protein	3		-	-	0.0
357	Two-component sensor histidine kinase	3		-	-	5.4
373	Sensory transduction histidine kinase	3		-	-	41.3
380	PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase	3		-	-	0.0
371	Methyl-accepting chemotaxis protein	3		-	-	0.0
396	PAS domain containing serine/threonine kinase	3		-	-	78.3
369	Hybrid sensor histidine kinase/response regulator	3		-	-	0.0
354	Nitrogen fixation negative regulator NifL	3		-	-	1.8
352	Uncharacterized protein	3		-	-	66.3
390	Sensory transduction histidine kinase	3		-	-	0.0
360	Two-component sensor histidine kinase	3		-	-	8.4
377	Two-component response regulator	3		-	-	5.7
378	Sensory transduction histidine kinase	3		-	-	0.0
351	Two-component sensor histidine kinase	3		-	-	10.6
366	Neuronal PAS domain protein 4	3		-	-	4.4
353	Uncharacterized protein	3		-	-	73.6
385	Transcriptional regulator, PpsR	3		-	-	0.0
349	Circadian locomoter output cycles protein kaput-like Protein	3		-	-	0.0
374	Sensory transduction histidine kinase	3		-	-	0.0
395	Methyl-accepting chemotaxis protein	3		-	-	0.0
372	Protein single-minded-like Protein	3		-	-	24.7
389	Two-component response regulator	3		-	-	7.9
368	Uncharacterized protein	3		-	-	7.1
381	Histidine kinase	3		-	-	9.1
367	Uncharacterized protein	3		-	-	5.9
383	Phytochrome	3		-	-	0.0
355	Two-component sensor kinase	3		-	-	3.4
370	Methyl-accepting chemotaxis protein	3		-	-	6.9
376	Regulatory components of sensory transductionsystem	3		-	-	6.8
391	Two-component oxygen-sensor histidine kinase	3		-	-	4.4
393	Methyl-accepting chemotaxis protein	3		-	-	7.6
364	Neuronal PAS domain-containing protein 4-like	3		-	-	42.3
359	Two-component hybrid sensor and regulator	3		-	-	0.0
362	Two-component sensor histidine kinase	3		-	-	0.0
375	Sensor histidine kinase/response regulator, putative	3		-	-	0.0
350	GGDEF domain-containing protein	3		-	-	0.0
392	Histidine kinase response regulator hybrid protein	3		-	-	0.0
356	Sensor histidine kinase	3		-	-	9.6
361	Two-component hybrid sensor and regulator	3		-	-	0.0
388	Sensory transduction histidine kinase	3		-	-	5.9
387	Sensor histidine kinase	3		-	-	0.0
394	Membrane-anchored chemotaxis sensory transducer	3		-	-	0.0
363	Histidine kinase	3		-	-	10.4
382	Sensory transduction histidine kinase	3		-	-	16.5
379	Sensory box histidine kinase, putative	3		-	-	10.3
384	Sensory transduction histidine kinase	3		-	-	10.4
397	Sensory transduction histidine kinase	3		-	-	82.1
507	Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding	2		-	-	0.0
441	Signal-transducing histidine kinase homolog	2		-	-	1.1
476	Sensory box histidine kinase/response regulator	2		-	-	0.0
435	Predicted protein	2		-	-	0.0
443	Erg potassium channel	2		-	-	0.0
508	Histidine kinase	2		-	-	0.0
470	Period	2		-	-	4.9
425	Sensor histidine kinase	2		-	-	0.0
455	Response receiver sensor histidine kinase, PAS domain-containing	2		-	-	0.0
483	Histidine kinase	2		-	-	0.0
467	Uncharacterized protein	2		-	-	0.0
415	Sensor histidine kinase, HAMP and PAS domain-containing	2		-	-	0.0
481	Chemotaxis protein	2		-	-	0.0
468	Hif-1	2		-	-	1.5
504	Histidine kinase	2		-	-	0.0
401	Aryl hydrocarbon receptor nuclear translocator type 1b	2		-	-	1.7
520	Multi-sensor hybrid histidine kinase	2		-	-	10.8
403	Diguanylate cyclase	2		-	-	0.0
510	Probable response regulatory protein	2		-	-	9.2
462	Predicted protein	2		-	-	0.0
439	Uncharacterized protein	2		-	-	3.2
526	Response receiver sensor protein serine/threonine phosphatase, PP2C family, PAS and PAS domain-containing	2		-	-	0.0
459	Histidine kinase	2		-	-	3.6
429	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
464	Hypoxia-inducible factor 1 subunit alpha,-like 2	2		-	-	1.1
493	Diguanylate cyclase and metal dependent phosphohydrolase	2		-	-	1.7
502	GAF domain protein	2		-	-	0.0
530	Response regulator	2		-	-	0.0
419	Sensory transduction histidine kinase	2		-	-	0.0
491	Histidine kinase	2		-	-	0.0
516	Sensory transduction histidine kinase	2		-	-	10.5
416	Sensor box histidine kinase	2		-	-	0.0
463	Hypoxia-inducible factor 1 alpha, putative	2		-	-	11.1
494	PAS sensor protein	2		-	-	10.0
487	Two-component sensor CbrA	2		-	-	0.0
519	Sll0779 protein	2		-	-	0.0
430	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
402	Diguanylate cyclase	2		-	-	0.0
488	Sensor histidine kinase TodS	2		-	-	0.0
461	Hypoxia-inducible factor 1 subunit alpha,-like 2	2		-	-	0.0
529	Putative diguanylate cyclase	2		-	-	0.0
426	Two-component system sensor histidine kinase	2		-	-	0.0
456	Uncharacterized protein	2		-	-	0.0
436	Putative hypoxia-inducible factor 1/neuronal pas domain protein npas1	2		-	-	7.6
448	Cyclic-di-AMP phosphodiesterase	2		-	-	3.6
503	Histidine kinase	2		-	-	9.5
410	Histidine kinase	2		-	-	0.0
450	Uncharacterized protein	2		-	-	40.9
420	Sensor histidine kinase of FgrL, PAS domain-containing	2		-	-	0.0
492	Histidine kinase	2		-	-	0.0
399	Aryl hydrocarbon receptor type 1	2		-	-	1.0
447	Sensory box histidine kinase SdeK	2		-	-	2.0
404	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
475	Sensor histidine kinase	2		-	-	0.0
501	Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing	2		-	-	7.7
497	Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing	2		-	-	7.4
484	Histidine kinase	2		-	-	0.0
515	Slr1385 protein	2		-	-	0.0
442	Sensor box histidine kinase	2		-	-	0.0
525	Histidine kinase	2		-	-	0.0
498	Response regulator	2		-	-	0.0
408	Two component system histidine kinase	2		-	-	9.2
479	Uncharacterized protein	2		-	-	39.4
482	Two-component system sensor histidine kinase/response regulator	2		-	-	4.7
407	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
444	Two-component sensor histidine kinase	2		-	-	3.7
446	Two-component sensor histidine kinase	2		-	-	0.0
471	Two-component hybrid sensor and regulator	2		-	-	0.0
505	Histidine kinase	2		-	-	0.0
438	Uncharacterized protein	2		-	-	10.3
480	Uncharacterized protein	2		-	-	45.3
473	Putative regulatory protein	2		-	-	8.3
457	GAF sensor signal transduction histidine kinase	2		-	-	7.0
427	Probable transcriptional regulator	2		-	-	0.0
465	Neuronal PAS domain protein 4	2		-	-	0.0
418	Sensory box sensor histidine kinase	2		-	-	5.1
440	Uncharacterized protein	2		-	-	4.1
458	GAF domain-containing protein	2		-	-	0.0
428	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
486	Histidine kinase	2		-	-	0.0
417	Histidine kinase sensor protein	2		-	-	0.0
406	C4-dicarboxylate transport sensor protein dctB	2		-	-	11.1
509	AraC family transcriptional regulator	2		-	-	0.0
533	Predicted protein	2		-	-	46.5
412	Hybrid signal transduction histidine kinase B	2		-	-	7.2
452	Voltage-dependent calcium channel subunit alpha-2/delta-3	2		-	-	0.0
490	Sensory transduction histidine kinase	2		-	-	10.9
422	Sensory transduction histidine kinase	2		-	-	0.0
434	Uncharacterized protein	2		-	-	3.7
531	Uncharacterized protein	2		-	-	30.8
521	Uncharacterized protein	2		-	-	0.0
424	Sensor histidine kinase, PAS domain-containing	2		-	-	0.0
454	Voltage-dependent calcium channel subunit alpha-2/delta-4	2		-	-	0.0
469	PAS domain-containing protein	2		-	-	0.0
432	Aryl-hydrocarbon receptor repressor a	2		-	-	38.1
513	Transcription activator of gluconeogenesis ERT1	2		-	-	2.2
400	Uncharacterized protein	2		-	-	2.9
523	Hybrid signal transduction histidine kinase A	2		-	-	9.2
414	Sensory transduction histidine kinase	2		-	-	6.5
511	ACR218Wp	2		-	-	3.0
496	PAS domain-containing protein	2		-	-	0.0
514	Uncharacterized protein	2		-	-	0.0
411	PAS domain-containing hybrid sensor histidine kinase/response regulator	2		-	-	0.0
499	Methyl-accepting chemotaxis protein	2		-	-	1.0
423	Uncharacterized protein	2		-	-	0.0
485	Histidine kinase	2		-	-	0.0
453	Calcium voltage-gated channel auxiliary subunit alpha2delta 1	2		-	-	13.1
466	Hypoxia-inducible factor 1-alpha	2		-	-	2.3
413	Hybrid signal transduction histidine kinase I	2		-	-	0.0
500	PleD-like-protein	2		-	-	0.0
532	Hypoxia-inducible factor 1 alpha, putative	2		-	-	41.8
421	Sensor histidine kinase, PAS domain-containing	2		-	-	0.0
524	Histidine kinase	2		-	-	0.0
451	Calcium channel, voltage-dependent, alpha 2/delta subunit 2b	2		-	-	3.5
478	Uncharacterized protein	2		-	-	13.9
534	Two-component sensor PprA	2		-	-	43.5
431	Uncharacterized protein	2		-	-	0.0
522	Protein kinase, putative	2		-	-	0.0
512	PAS/PAC sensor hybrid histidine kinase	2		-	-	10.4
433	Uncharacterized protein	2		-	-	44.4
477	Probable serine/threonine-protein kinase DDB_G0280133	2		-	-	29.3
445	Sporulation kinase A	2		-	-	0.0
409	Sensor histidine kinase, PAS, PAS and PAS domain-containing	2		-	-	0.0
506	IcfG protein	2		-	-	0.0
460	Neuronal PAS domain-containing protein 4-like	2		-	-	0.8
489	Sensor histidine kinase, PAS and GAF domain-containing	2		-	-	0.0
517	Slr0302 protein	2		-	-	9.5
472	Two-component hybrid sensor and regulator	2		-	-	0.0
495	Response receiver sensor protein serine/threonine phosphatase, PP2C family, PAS and PAS domain-containing	2		-	-	0.0
528	Histidine kinase	2		-	-	5.5
518	Histidine kinase	2		-	-	7.9
527	Guanylate cyclase	2		-	-	0.0
398	Aryl hydrocarbon receptor nuclear translocator-like 2	2		-	-	10.3
474	Sensory box histidine kinase/response regulator	2		-	-	0.0
405	Sensory box histidine kinase	2		-	-	3.9
449	Predicted protein	2		-	-	32.8
544	Hybrid signal transduction histidine kinase H	1		-	-	0.0
647	PAS sensor protein	1		-	-	0.0
604	Uncharacterized protein	1		-	-	0.0
675	Putative DNA-binding protein	1		-	-	0.0
582	Uncharacterized protein	1		-	-	0.0
650	Sensory box sensor histidine kinase	1		-	-	0.0
620	Uncharacterized protein	1		-	-	0.0
692	Putative two-component system sensor kinase/response regulator	1		-	-	0.0
579	PAS domain-containing serine/threonine kinase	1		-	-	0.0
648	Sensory histidine protein kinase	1		-	-	0.0
610	Uncharacterized protein	1		-	-	0.0
636	Uncharacterized protein	1		-	-	0.0
626	Sensory transduction histidine kinase	1		-	-	0.0
656	Sensory transduction histidine kinase	1		-	-	0.0
688	Predicted protein	1		-	-	0.0
661	Uncharacterized protein	1		-	-	0.0
598	C4-dicarboxylate transport sensor protein DctB, putative	1		-	-	0.0
542	Sensory histidine protein kinase	1		-	-	0.0
630	Uncharacterized protein	1		-	-	0.0
602	Uncharacterized protein	1		-	-	0.0
616	Uncharacterized protein	1		-	-	0.0
663	PAS sensor protein	1		-	-	0.0
694	Diguanylate cyclase with PAS sensory domain	1		-	-	0.0
584	Uncharacterized protein	1		-	-	0.0
687	Predicted protein	1		-	-	0.0
597	BfiS	1		-	-	0.0
547	ATPase, putative	1		-	-	0.0
575	Uncharacterized protein	1		-	-	0.0
607	Two-component hybrid sensor and regulator	1		-	-	0.0
644	Uncharacterized protein	1		-	-	0.0
679	Predicted protein	1		-	-	0.0
550	Nitrogen regulation protein ntrY	1		-	-	0.0
682	Uncharacterized protein	1		-	-	0.0
592	PHOTB3 phototropin blue light photoreceptor	1		-	-	0.0
608	Sensor histidine kinase, Cache_1 and HAMP domain-containing	1		-	-	0.0
548	PAS sensor protein	1		-	-	0.0
536	Uncharacterized protein	1		-	-	0.0
556	Putative histidine kinase PhoR1	1		-	-	0.0
588	Uncharacterized protein	1		-	-	0.0
561	Nitrogen regulation protein NtrB	1		-	-	0.0
698	Chemotaxis signal transduction system methyl accepting sensory transducer	1		-	-	0.0
642	Histidine kinase response regulator hybrid protein	1		-	-	0.0
587	Uncharacterized protein	1		-	-	0.0
697	Energy taxis modulating methyl accepting sensory transducer	1		-	-	0.0
563	Histidine kinase sensor protein	1		-	-	0.0
594	Sensor histidine kinase, PAS and PAS domain-containing	1		-	-	0.0
684	Predicted protein	1		-	-	0.0
591	Sensor histidine kinase	1		-	-	0.0
681	Blr6052 protein	1		-	-	0.0
668	Blue-light receptor phototropin 2	1		-	-	0.0
615	Neuronal PAS domain-containing protein 4B	1		-	-	0.0
625	Uncharacterized protein	1		-	-	0.0
564	Uncharacterized protein	1		-	-	0.0
593	BfiS	1		-	-	0.0
655	Diguanylate cyclase with PAS/PAC sensor	1		-	-	0.0
683	Guanylate cyclase	1		-	-	0.0
667	Sensory transduction histidine kinase	1		-	-	0.0
559	PAS/PAC sensor signal transduction histidine kinase	1		-	-	0.0
670	PAS sensor protein	1		-	-	0.0
562	Two-component sensor histidine kinase	1		-	-	0.0
539	C4-dicarboxylate transport sensor protein	1		-	-	0.0
635	Histidine kinase	1		-	-	0.0
643	Two-component hybrid sensor and regulator	1		-	-	0.0
676	Nuclear receptor coactivator 3	1		-	-	0.0
641	Cytokinin receptor AtCKI2-like protein	1		-	-	0.0
619	Uncharacterized protein	1		-	-	0.0
691	PAS sensor protein	1		-	-	0.0
581	Uncharacterized protein	1		-	-	0.0
568	Putative methyl-accepting chemotaxis protein	1		-	-	0.0
567	Putative methyl-accepting chemotaxis protein	1		-	-	0.0
664	Predicted protein	1		-	-	0.0
693	Diguanylate cyclase with PAS sensory domain	1		-	-	0.0
555	Alkaline phosphatase synthesis sensor protein PhoR	1		-	-	0.0
583	Uncharacterized protein	1		-	-	0.0
570	Predicted protein	1		-	-	0.0
659	Two-component hybrid sensor and regulator	1		-	-	0.0
629	Serine phosphatase RsbU	1		-	-	0.0
662	Sensor histidine kinase, HAMP and PAS domain-containing	1		-	-	0.0
639	PAS sensor protein	1		-	-	0.0
603	voltage-dependent calcium channel subunit alpha-2/delta-1	1		-	-	0.0
535	Uncharacterized protein	1		-	-	0.0
543	Hybrid signal transduction histidine kinase E	1		-	-	0.0
576	Neuronal PAS domain protein 4a	1		-	-	0.0
601	Uncharacterized protein	1		-	-	0.0
541	Two-component sensor PprA	1		-	-	0.0
609	Sensor histidine kinase, Cache_1 and HAMP domain-containing	1		-	-	0.0
549	Putative nitrogen regulation protein NtrY	1		-	-	0.0
660	Diguanylate cyclase with PAS/PAC sensor	1		-	-	0.0
574	Uncharacterized protein	1		-	-	0.0
633	Sensor histidine kinase, HAMP domain-containing	1		-	-	0.0
677	Blue-light receptor phototropin 2	1		-	-	0.0
645	Histidine kinase	1		-	-	0.0
678	Sensory transduction histidine kinase	1		-	-	0.0
631	Hybrid sensor kinase RscS	1		-	-	0.0
621	Protein single-minded-like Protein	1		-	-	0.0
651	Sensory transduction histidine kinase	1		-	-	0.0
666	Uncharacterized protein	1		-	-	0.0
613	Uncharacterized protein	1		-	-	0.0
595	Sensor histidine kinase, PAS and PAS domain-containing	1		-	-	0.0
623	Uncharacterized protein	1		-	-	0.0
685	Regulatory-associated protein of TOR 1	1		-	-	0.0
653	Uncharacterized protein	1		-	-	0.0
572	Uncharacterized protein	1		-	-	0.0
611	Uncharacterized protein	1		-	-	0.0
589	Uncharacterized protein	1		-	-	0.0
699	Methyl accepting sensory transducer with Cache_2 small molecule binding domain	1		-	-	0.0
649	PAS sensor protein	1		-	-	0.0
560	Nitrogen-responsive two component signal transduction system histidine kinase with PAS sensory domain GlnL	1		-	-	0.0
577	Predicted protein	1		-	-	0.0
545	Uncharacterized protein DHKH	1		-	-	0.0
674	Nuclear receptor coactivator	1		-	-	0.0
605	Predicted protein	1		-	-	0.0
578	Uncharacterized protein	1		-	-	0.0
551	Signal-transducing histidine kinase	1		-	-	0.0
566	Methyl-accepting chemotaxis protein	1		-	-	0.0
695	Chemotaxis signal transduction system methyl accepting sensory transducer	1		-	-	0.0
585	Sensory box protein	1		-	-	0.0
553	Sensor histidine kinase PilS, PAS domain-containing	1		-	-	0.0
689	Hybrid signal transduction histidine kinase L	1		-	-	0.0
599	Sensor histidine kinase	1		-	-	0.0
672	Hybrid signal transduction histidine kinase A	1		-	-	0.0
596	Sensor histidine kinase, PAS domain-containing	1		-	-	0.0
686	Blr6052 protein	1		-	-	0.0
617	Uncharacterized protein	1		-	-	0.0
658	Histidine kinase response regulator hybrid protein	1		-	-	0.0
628	Putative regulatory protein	1		-	-	0.0
618	Uncharacterized protein	1		-	-	0.0
640	Glr3986 protein	1		-	-	0.0
569	Uncharacterized protein	1		-	-	0.0
657	Sensory transduction histidine kinase	1		-	-	0.0
627	Sensory transduction histidine kinase	1		-	-	0.0
665	Glr3986 protein	1		-	-	0.0
554	Phosphate regulon sensor histidine kinase, putative	1		-	-	0.0
637	Sensor histidine kinase response regulator, PAS and PAS domain-containing	1		-	-	0.0
673	Uncharacterized protein	1		-	-	0.0
680	Sensory transduction histidine kinase	1		-	-	0.0
552	Sensory transduction histidine kinase	1		-	-	0.0
590	C4-dicarboxylate transport sensor protein dctB	1		-	-	0.0
671	Uncharacterized protein	1		-	-	0.0
638	Chromosome 8, whole genome shotgun sequence	1		-	-	0.0
646	PAS sensor protein	1		-	-	0.0
614	Uncharacterized protein	1		-	-	0.0
696	Energy taxis modulating methyl accepting sensory transducer with Cache_2 sensory domain	1		-	-	0.0
586	Predicted protein	1		-	-	0.0
558	C4-dicarboxylate transport sensor protein	1		-	-	0.0
540	Sensory transduction histidine kinase	1		-	-	0.0
669	Uncharacterized protein	1		-	-	0.0
632	Two component system histidine kinase	1		-	-	0.0
600	Predicted protein	1		-	-	0.0
624	Uncharacterized protein	1		-	-	0.0
565	Uncharacterized protein	1		-	-	0.0
654	Sensory box sensor histidine kinase	1		-	-	0.0
557	Histidine kinase sensor protein	1		-	-	0.0
634	Two component system histidine kinase	1		-	-	0.0
537	Uncharacterized protein	1		-	-	0.0
573	Uncharacterized protein	1		-	-	0.0
652	Sensory transduction histidine kinase	1		-	-	0.0
580	Uncharacterized protein	1		-	-	0.0
690	Sensory transduction histidine kinase	1		-	-	0.0
622	Hypoxia-inducible factor 1 subunit alpha	1		-	-	0.0
538	Uncharacterized protein	1		-	-	0.0
612	Protein TWIN LOV 1	1		-	-	0.0
571	Uncharacterized protein	1		-	-	0.0
606	Calcium voltage-gated channel auxiliary subunit alpha2delta 4	1		-	-	0.0
546	Predicted protein	1		-	-	0.0

Network disruptions

Functional Families

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