The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Probable tRNA modification gtpase trme; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Aminomethyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
4 P25285 (/ISS) Q8CFA2 (/ISS) Q8CFA2 (/ISS) Q9TSZ7 (/ISS)
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
2 P48728 (/IMP) P48728 (/IMP)
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
2 Q8CFA2 (/ISO) Q8CFA2 (/ISO)
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
2 P48728 (/TAS) P48728 (/TAS)
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
1 P28337 (/IDA)
Aminomethyltransferase activity GO:0004047
Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
1 C8VSU4 (/RCA)
Lipoic acid binding GO:0031405
Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid.
1 P25285 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine decarboxylation via glycine cleavage system GO:0019464
The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
4 P25285 (/ISS) Q8CFA2 (/ISS) Q8CFA2 (/ISS) Q9TSZ7 (/ISS)
Glycine catabolic process GO:0006546
The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
3 P25285 (/TAS) P48728 (/TAS) P48728 (/TAS)
Glycine decarboxylation via glycine cleavage system GO:0019464
The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
2 P48728 (/IMP) P48728 (/IMP)
Glycine decarboxylation via glycine cleavage system GO:0019464
The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
2 Q8CFA2 (/ISO) Q8CFA2 (/ISO)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 C8VSU4 (/RCA)
Glycine decarboxylation via glycine cleavage system GO:0019464
The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
1 P28337 (/IDA)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 A0A024R2U7 (/IDA) A0A024R2U7 (/IDA) A0A1B0GTB6 (/IDA) A0A1B0GTV8 (/IDA) A0A1B0GVP5 (/IDA) B3KTU4 (/IDA) H0Y695 (/IDA) P25285 (/IDA) P48728 (/IDA) P48728 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
9 A0A024R2U7 (/IDA) A0A024R2U7 (/IDA) A0A1B0GTB6 (/IDA) A0A1B0GTV8 (/IDA) A0A1B0GVP5 (/IDA) B3KTU4 (/IDA) H0Y695 (/IDA) P48728 (/IDA) P48728 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P28337 (/IC) P48728 (/IC) P48728 (/IC)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P25285 (/TAS) P48728 (/TAS) P48728 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q8CFA2 (/ISO) Q8CFA2 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8CFA2 (/HDA) Q8CFA2 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8CFA2 (/ISO) Q8CFA2 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 P48728 (/TAS) P48728 (/TAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 P25285 (/TAS)