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CATH Superfamily 3.10.290.10

RNA-binding S4 domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RNA-binding S4 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Pseudouridine synthase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA pseudouridine(2605) synthase. [EC: 5.4.99.22]
23S rRNA uridine(2605) = 23S rRNA pseudouridine(2605).
  • Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine.
 16052 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025 A0A026V025
(16042 more...)
23S rRNA pseudouridine(2604) synthase. [EC: 5.4.99.21]
23S rRNA uridine(2604) = 23S rRNA pseudouridine(2604).
  • The enzyme is not completely specific for uridine(2604) and can, to a small extent, also react with uridine(2605).
 1993 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713 A0A024L713
(1983 more...)
16S rRNA pseudouridine(516) synthase. [EC: 5.4.99.19]
16S rRNA uridine(516) = 16S rRNA pseudouridine(516).
  • The enzyme is specific for uridine(516) in 16S rRNA.
  • In vitro, the enzyme does not modify free 16S rRNA.
  • The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
 36 A0A0H3Q2B7 A0A0H3Q2B7 A0A0H3Q2B7 A0A0H3Q2B7 A0A0H3Q2B7 A0A0H3Q2B7 A0A0H6XR71 A0A0H6XR71 A0A0H6XR71 A0A0H6XR71
(26 more...)