The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 270: Blast:Tyrosine-protein kinase Src-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 A1ZAY1 (/IPI)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
1 A1ZAY1 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
1 A1ZAY1 (/IMP)
Negative regulation of hippo signaling GO:0035331
Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
1 A1ZAY1 (/IMP)
Establishment of epithelial cell planar polarity GO:0090163
The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.
1 A1ZAY1 (/IMP)
Protein localization involved in establishment of planar polarity GO:0090251
Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
1 A1ZAY1 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 A1ZAY1 (/IDA)
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
1 A1ZAY1 (/IDA)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
1 A1ZAY1 (/IDA)
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