CATH Superfamily 2.30.30.40

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Sorbin and SH3 domain-containing protein 1 isoform 2	1520	3D	2lj1A00	-	85.0
2	abl interactor 1 isoform X1	1184	3D	2ed0A00	-	89.0
3	Sorbin and SH3 domain-containing protein 1 isoform 2	938	3D	4lnpA00	-	69.9
4	Sorbin and SH3 domain-containing protein 1 isoform 2	931	3D	4ln2A00	-	79.8
5	SLIT-ROBO Rho GTPase-activating protein 1 isoform 2	834	3D	2dl8A00	-	73.9
6	RIMS-binding protein 2 isoform X1	811	3D	1wieA01	-	93.2
10	Tyrosine-protein kinase	772	3D	1opkA01	-	88.9
7	nebulin isoform X1	772	3D	4f14A00	-	83.0
8	Disks large homolog 1 isoform 2	764		-	-	95.0
9	Breast cancer anti-estrogen resistance 1	755	3D	1wyxB00	-	92.7
11	Microtubule-actin cross-linking factor 1	694		-	-	74.5
12	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2	662	3D	2rquA00	-	85.0
14	Kinase C and casein kinase substrate in neurons protein	661	3D	2x3xE00	-	86.9
13	Alkylphosphonate utilization protein PhnA	660	3D	2aklA02	-	79.7
15	Voltage-dependent L-type calcium channel subunit beta-2	637	3D	4deyA01	-	73.9
16	RIMS-binding protein 2 isoform X2	633	3D	2csiA00	-	89.2
17	Formin-binding protein 1-like isoform 1	629	3D	2ct4A00	-	78.0
18	Brain-specific angiogenesis inhibitor 1-associated protein 2	629	3D	3rnjA00	-	83.4
19	Chemotaxis protein CheW	622		-	-	67.1
20	SH3 and PX domain-containing protein 2A	621		-	-	77.1
21	Putative sam and sh3 domain-containing protein 1	609	3D	2ebpA00	-	66.5
23	RIMS-binding protein 2 isoform F	581	3D	4z89J00	-	91.4
22	Tyrosine-protein kinase	568	3D	2yt6A01	-	72.3
24	Intersectin 1	560	3D	6gbuH00	-	85.8
25	SH3 and multiple ankyrin repeat domains protein 2	556	3D	6cpkA00	-	88.8
26	Putative tight junction protein ZO-1	541	3D	3tszA02	-	35.6
27	Disks large homolog 3 isoform 1	500		-	-	77.0
28	endophilin-B2 isoform X1	482	3D	1x43A01	-	57.0
29	myc box-dependent-interacting protein 1 isoform X2	450	3D	5i22A00	-	82.2
30	rho GTPase-activating protein 32 isoform X2	437		-	-	70.3
36	Spectrin alpha chain, non-erythrocytic 1	436	3D	5fwcA00	-	71.3
32	Putative C-Jun-amino-terminal kinase-interacting protein 2	430	3D	2fpfD00	-	85.7
31	SH3 and PX domain-containing protein 2A	429	3D	2egcA00	-	81.5
34	Rho guanine nucleotide exchange factor GEF	416	3D	2eswB00	-	71.5
33	FCH and double SH3 domains protein 2	412	3D	6gbuG00	-	91.9
35	SH3 domain containing protein	401		-	-	64.1
37	Rho guanine nucleotide exchange factor 9	392	3D	2ysqA00	-	57.7
38	kalirin isoform X1	391	3D	1wfwA00	-	85.0
39	Vav guanine nucleotide exchange factor 3	385	3D	2kbtA00	-	74.2
40	kalirin isoform X1	374	3D	1u3oA01	-	79.1
41	Intersectin 1	372	3D	3jv3A01	-	69.4
42	SH3 and PX domain-containing protein 2A	368	3D	2dnuA00	-	83.2
43	Chemotaxis protein CheW	365		-	-	80.8
44	E3 ubiquitin-protein ligase MIB2, putative	364		-	-	93.6
45	Short stop, isoform K	357		-	-	63.6
46	Drebrin-like protein isoform B	356		-	-	89.7
47	Disks large homolog 2 isoform 3	355		-	-	77.8
48	Chemotaxis protein CheA, putative	353		-	-	95.1
50	RAS p21 protein activator 1	348	3D	4fssC00	-	62.6
49	Voltage-dependent L-type calcium channel subunit beta-3	345	3D	1vyuB01	-	82.2
51	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma	340	3D	2hspA00	-	85.9
53	endophilin-A1 isoform X2	331	3D	2dbmA00	-	72.0
52	Ubiquitin-associated and SH3 domain-containing protein B	329	3D	2e5kA01	-	91.8
54	Putative e3 ubiquitin-protein ligase mind-bomb	323		-	-	75.8
55	rho GTPase-activating protein 26 isoform X1	315	3D	1ugvA00	-	85.6
57	Dedicator of cytokinesis protein 4	314	3D	2rqrA00	-	64.5
56	rho GTPase-activating protein 12 isoform X1	311		-	-	67.4
58	Disks large homolog 1 isoform X1	307		-	-	65.2
59	SH3 and PX domain-containing protein 2A	303		-	-	72.6
60	FCH and double SH3 domains protein 2	302	3D	2dl5A00	-	97.1
61	Cytoplasmic protein	300	3D	2jw4A00	-	79.8
62	caskin-2 isoform X1	294	3D	2ke9A00	-	83.6
65	adapter molecule crk isoform X1	290	3D	2ggrA00	-	69.9
66	dynamin-binding protein isoform X1	289	3D	4cc7M00	-	89.0
67	Growth factor receptor-bound protein 2	289	3D	2w0zA00	-	82.6
63	Putative E3 ubiquitin-protein ligase SH3RF1	287		-	-	77.9
64	Plectin a	287	3D	3pe0B03	-	78.9
72	Unconventional Myosin IB	277	3D	2xmfA00	-	97.3
68	Voltage-dependent L-type calcium channel subunit beta-1 isoform 1	271	3D	4zw2A01	-	61.8
71	Epidermal growth factor receptor kinase substrate 8	267	3D	1i0cB00	-	87.9
75	phosphatidylinositol 3-kinase regulatory subunit alpha	266	3D	3i5sD00	-	88.1
69	MAGUK p55 subfamily member 6	265		-	-	73.3
70	Alpha- 1,6	261	3D	2de0X03	-	94.2
76	Growth factor receptor-bound protein 2	260	3D	1griB01	-	67.4
73	SH3 and cysteine-rich domain-containing protein 2	257	3D	2dl4A00	-	75.3
83	Tyrosine-protein kinase	257	3D	4k11A01	-	62.9
74	E3 ubiquitin-protein ligase HERC2 isoform X1	254		-	-	85.0
95	Tyrosine-protein kinase	253	3D	6nmwA00	-	83.6
77	spermatogenesis-associated protein 13 isoform X2	250	3D	3nmzD00	-	60.0
79	Mitogen-activated protein kinase kinase kinase	247	3D	5k28B00	-	72.8
78	Putative e3 ubiquitin-protein ligase mib2	242		-	-	82.0
80	Peripheral plasma membrane protein CASK isoform X2	236		-	-	41.4
81	Tight junction protein ZO-2 isoform 2	231		-	-	29.2
87	Src substrate cortactin	230	3D	3ulrB00	-	79.1
82	SH3 and PX domain-containing protein 2B	230		-	-	85.3
84	dynamin-binding protein isoform X1	225	3D	1ug1A00	-	83.0
86	signal transducing adapter molecule 2	225	3D	2l0aA00	-	71.5
85	E3 ubiquitin-protein ligase HECTD1 isoform X1	224	3D	3dkmA00	-	70.3
88	Periplakin	218		-	-	97.8
89	SH3 domain-containing kinase-binding protein 1	216	3D	2ydlA00	-	74.4
90	E3 ubiquitin-protein ligase MIB1 isoform X1	211		-	-	52.1
91	Putative E3 ubiquitin-protein ligase SH3RF1	210		-	-	66.8
92	Uncharacterized protein, isoform B	208		-	-	23.2
93	Protein kinase activator Bem1	203	3D	2rqwA01	-	84.7
94	SH3 domain-containing kinase-binding protein 1	201	3D	2o2oA00	-	76.8
96	Neutrophil cytosol factor 2	189	3D	2dmoA00	-	70.8
97	Putative src kinase-associated phosphoprotein 2	186		-	-	89.4
98	Protein arginine N-methyltransferase 2 isoform 1	185		-	-	44.8
100	SH3 domain-containing YSC84-like protein 1	181	3D	2a08B00	-	93.0
99	Uncharacterized protein, isoform C	181		-	-	20.4
112	SH3 domain-containing kinase-binding protein 1	178	3D	2mcnA00	-	76.6
102	Desmoplakin a	176	3D	3r6nB03	-	61.6
101	Rho GTPase activating protein 9	175		-	-	83.1
103	Amphiphysin	173		-	-	75.6
104	Bacterial SH3 domain protein	169		-	-	14.1
108	Vav guanine nucleotide exchange factor 3	169	3D	1k1zA00	-	75.8
105	MAGUK p55 subfamily member 5	168		-	-	57.6
106	disks large homolog 4 isoform X2	166		-	-	43.1
107	FCH and double SH3 domains 1	164		-	-	86.6
110	Cytoplasmic protein	163	3D	2fryA00	-	86.0
109	Peroxisomal biogenesis factor 13	161	3D	1wxuA01	-	92.1
111	Rho guanine nucleotide exchange factor GEF	157		-	-	73.9
113	unconventional myosin-VIIa	156	3D	3pvlA05	-	70.9
114	Rho GTPase activating protein 42	154		-	-	58.0
115	Small G protein signaling modulator 3 homolog	149	3D	2yuoA00	-	59.1
116	Sorting nexin	145		-	-	77.2
117	SH3 domain-binding protein 4	145		-	-	62.0
121	Neutrophil cytosol factor 1	144	3D	1wlpB02	-	82.2
118	Putative E3 ubiquitin-protein ligase SH3RF1	142		-	-	65.7
119	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma	142	3D	2eqiA00	-	92.3
120	dynamin-binding protein isoform X1	140		-	-	57.5
122	intersectin-1 isoform X2	138	3D	6h5tB00	-	82.2
123	Ephexin-1 isoform X1	134		-	-	36.2
124	obscurin isoform X2	133	3D	1v1cA00	-	48.1
126	Cytoplasmic protein	132	3D	2js0A00	-	77.3
128	Peroxisomal membrane protein Pex13	131	3D	2v1rB00	-	90.4
127	neutrophil cytosol factor 1	130	3D	1wlpB01	-	82.4
125	Tyrosine-protein kinase	130		-	-	51.5
129	MAGUK p55 subfamily member 4	122		-	-	45.4
130	Discs large 5, isoform A	121		-	-	66.0
132	jouberin isoform X2	119	3D	4esrB00	-	90.8
133	FYN-binding protein-like isoform X2	117	3D	2gtoA01	-	76.2
131	Guanine nucleotide exchange factor VAV2 isoform 2	117		-	-	40.6
182	Tyrosine-protein kinase Fyn	116	3D	4znxD00	-	72.0
134	src-like-adapter isoform X1	114	3D	2cudA00	-	86.8
135	55 kDa erythrocyte membrane protein	111		-	-	58.2
136	Rho GTPase activating protein 4	110		-	-	96.4
137	Uncharacterized protein, isoform G	110		-	-	20.0
157	adapter molecule crk isoform X1	107	3D	5l23A00	-	63.7
138	dynamin-binding protein isoform X1	106		-	-	83.9
152	Tyrosine-protein kinase	106	3D	4d8kA01	-	84.0
146	Tyrosine-protein kinase	105	3D	1jegA00	-	57.5
139	Hematopoietic cell-specific Lyn substrate 1	105		-	-	75.2
149	neutrophil cytosol factor 4	104	3D	2dybB02	-	81.3
140	vinexin isoform X2	104		-	-	33.5
141	SH3 and PX domain-containing protein 2A	103		-	-	87.7
145	Tyrosine-protein kinase	102	3D	1x6gA00	-	89.5
144	Disks large 1 isoform X3	102	3D	3uatA01	-	36.2
142	melanoma inhibitory activity protein 2 isoform X2	102		-	-	78.1
143	Caspase recruitment domain family member 10	101		-	-	79.5
147	Cas scaffold protein family member 4	100	3D	2creA00	-	70.7
150	Proline-serine-threonine phosphatase interacting protein 1	98	3D	2dilA00	-	96.3
148	Caspase recruitment domain family member 11	98		-	-	62.6
151	Tyrosine-protein kinase	95		-	-	71.6
153	rho guanine nucleotide exchange factor 26	95	3D	1x6bA01	-	67.1
154	Alpha spectrin, isoform C	93		-	-	66.5
156	FYN-binding protein-like isoform X1	92	3D	1ri9A00	-	78.5
158	Osteoclast-stimulating factor 1	92	3D	3ehrB01	-	27.1
155	FCH and double SH3 domains protein	92		-	-	75.8
160	dynamin-binding protein isoform X1	88	3D	4glmD00	-	80.9
159	MAGUK p55 subfamily member 7	85		-	-	42.5
163	crk-like protein isoform X1	84	3D	2lqwA02	-	42.4
161	Actin polymerization protein Bzz1	83		-	-	87.5
166	RIM-binding protein, isoform F	82		-	-	52.1
165	dynamin-binding protein isoform X1	82		-	-	84.1
164	Cell division control protein	82		-	-	85.2
162	MIA SH3 domain ER export factor 3	82		-	-	75.5
167	SH3 and cysteine-rich domain-containing protein 3 isoform X1	81		-	-	66.4
168	SH3 domain protein Cyk3	80		-	-	77.4
176	Tyrosine-protein kinase	80	3D	2rnaA00	-	77.2
175	Melanoma-derived growth regulatory protein	79	3D	5ixbB00	-	72.5
169	Mitogen-activated protein kinase kinase kinase	79		-	-	79.0
170	ABI gene family member 3	78		-	-	95.6
171	Nephrocystin 1	78	3D	1s1nA00	-	93.0
172	Amphiphysin, isoform B	75		-	-	82.3
181	GRB2-related adapter protein 2	75	3D	2w10B00	-	46.7
173	E3 ubiquitin-protein ligase SH3RF2 isoform X1	75	3D	2djqA00	-	77.0
174	rho guanine nucleotide exchange factor 37	74		-	-	86.1
177	Rho guanine nucleotide exchange factor GEF	72		-	-	97.7
178	SH3 and multiple ankyrin repeat domains protein	71		-	-	81.5
179	PML-RARA regulated adaptor molecule 1	71		-	-	46.6
180	epidermal growth factor receptor kinase substrate 8-like protein 2	70	3D	1wxbA00	-	76.3
183	Epidermal growth factor receptor kinase substrate 8	66		-	-	80.2
185	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2	65		-	-	68.8
184	Protein kinase activator Bem1	65		-	-	66.5
187	Neutrophil cytosolic factor 2	64	3D	1k4uS00	-	52.2
186	Nitric oxide synthase trafficking	64	3D	2yunA00	-	78.3
188	Insulin receptor tyrosine kinase substrate	63		-	-	69.2
189	BAR adaptor protein RVS167	63		-	-	75.4
190	Tyrosine-protein kinase	61		-	-	67.6
192	Uncharacterized protein, isoform C	59		-	-	17.5
191	E3 ubiquitin-protein ligase SH3RF2 isoform X2	59		-	-	75.6
194	SH3 and PX domains 2A	58	3D	2ekhA00	-	59.2
193	Rho guanine nucleotide exchange factor 38	58		-	-	76.2
195	epidermal growth factor receptor kinase substrate 8-like protein 3	57	3D	1wxtA00	-	82.1
199	Sorting nexin	56	3D	2enmA00	-	36.6
196	Chemotaxis protein CheV	56		-	-	71.0
198	Guanine nucleotide exchange factor DBS	55		-	-	51.1
197	Tyrosine-protein kinase	55		-	-	51.2
202	Tight junction protein 3	55	3D	3kfvA01	-	58.0
201	Myosin XVA	54		-	-	74.4
200	SH3 domain containing 19	54		-	-	27.6
203	Cdc42-interacting protein 4, isoform F	53		-	-	87.5
213	High osmolarity signaling protein SHO1	53	3D	2vknA00	-	88.5
204	Amidase	52		-	-	10.6
206	GRB2-related adapter protein 2 isoform X1	51		-	-	25.7
205	SH3 domain containing 19	51		-	-	36.2
207	CLUMA_CG020965, isoform A	51		-	-	75.7
208	Tyrosine-protein kinase	51		-	-	82.3
217	Tyrosine-protein kinase	50	3D	2d8jA00	-	71.8
212	NADPH oxidase activator 1	50		-	-	78.5
211	Tyrosine-protein kinase	50		-	-	90.8
216	growth arrest-specific protein 7 isoform X1	50	3D	2lx7A00	-	86.4
209	Abl interactor 2	50		-	-	22.2
210	Karst, isoform B	50		-	-	47.9
215	MAGUK p55 subfamily member 3	49		-	-	39.5
214	SH3 domain-containing protein 19 isoform X2	49		-	-	38.2
218	Myosin light chain kinase, smooth muscle	46		-	-	52.3
219	NADPH oxidase organizer 1	45		-	-	89.2
221	SH3 and cysteine-rich domain-containing protein 2	44		-	-	85.7
220	FYN binding protein 2	44		-	-	77.7
222	SH3 domain-containing protein Dlish	43		-	-	59.7
224	Src like adaptor 2	43	3D	4m4zA01	-	94.2
223	Caspase recruitment domain family, member 14	43		-	-	89.6
225	Phosphonoacetate hydrolase	42		-	-	34.9
226	Chemotaxis protein CheV	42		-	-	25.1
227	Uncharacterized protein, isoform B	41		-	-	15.1
229	Tyrosine-protein kinase	41	3D	2kgtA00	-	94.8
228	RUN and SH3 domain containing 2	40		-	-	34.4
232	RIMS-binding protein 3A-like	38	3D	2egeA00	-	85.0
230	Uncharacterized protein, isoform C	37		-	-	8.9
231	Rho GTPase activating protein 27	37		-	-	29.6
233	NADPH oxidase organizer 1	36		-	-	84.2
235	Myosin VIIb	35	3D	5f3yA05	-	38.7
234	Tyrosine-protein kinase	35		-	-	84.5
236	N-acetylmuramoyl-L-alanine amidase	35	3D	5o1qA00	-	17.0
237	SH3 and cysteine rich domain 3	33		-	-	47.4
238	NADPH oxidase organizer 1	32		-	-	71.2
239	NCK interacting protein with SH3 domain	30		-	-	12.2
256	Actin cytoskeleton-regulatory complex protein SLA1	30	3D	2v1qB00	-	82.8
243	Non-receptor tyrosine-protein kinase TNK1 isoform X1	29		-	-	84.4
241	Menage a trois, isoform C	29		-	-	32.6
240	SH3 domain containing 19	29		-	-	36.9
242	Actin binding protein	29		-	-	83.6
245	N-acetylmuramoyl-l-alanine amidase	28		-	-	6.8
244	Peptidase, M23/M37 family	28		-	-	19.8
246	RIMS-binding protein 3A-like	27		-	-	87.3
266	SLIT-ROBO Rho GTPase-activating protein 2	27	3D	4rugB00	-	56.1
250	Dynamin associated protein isoform Dap160-2	27		-	-	14.4
247	Rho-type guanine nucleotide exchange factor, isoform A	27		-	-	13.6
248	Ephexin, isoform D	27		-	-	16.9
249	Activated Cdc42 kinase-like	27		-	-	92.4
252	HECT domain and RCC1 family domain containing protein	26		-	-	47.2
251	Chemotaxis protein CheW	26		-	-	68.1
253	Tyrosine-protein kinase	26		-	-	73.9
271	Protein BZZ1	25	3D	2a28D00	-	68.8
255	Tyrosine-protein kinase	25		-	-	65.1
283	NAP1-binding protein 2	25	3D	2lcsA00	-	76.6
254	Myosin I MyoA/Myo5	25		-	-	85.8
258	Chemotaxis protein CheW	24		-	-	10.1
257	Abl interactor 2	24		-	-	15.6
262	RUN and SH3 domain containing 1	24		-	-	33.1
259	Protein BOI2	24		-	-	80.3
261	Chemotaxis protein CheV	24		-	-	0.0
260	neutrophil cytosol factor 2 isoform X1	24		-	-	51.4
268	Uncharacterized protein	23		-	-	66.3
265	Myoblast city, isoform B	23		-	-	22.2
267	E3 ubiquitin-protein ligase HECTD1 isoform X3	23		-	-	43.5
264	HECT E3 ubiquitin ligase	23		-	-	93.3
263	SH3 domain-containing protein 21	23		-	-	36.8
277	Actin-binding protein	23	3D	2rpnA00	-	61.4
270	Blast:Tyrosine-protein kinase Src-1	22		-	-	50.5
269	SH3 adapter protein SPIN90	22		-	-	14.6
274	[PSI+] inducibility protein 3	22	3D	1zx6A00	-	62.2
273	Actin binding protein	21		-	-	72.4
272	Chemotaxis protein CheW	21		-	-	6.5
276	CheW-like protein	20		-	-	0.0
275	Chemotaxis protein CheW	20		-	-	44.7
278	SAM domain, SH3 domain and nuclear localization signals 1	20		-	-	38.6
279	Spectrin beta chain, non-erythrocytic	20		-	-	75.1
280	Dreadlocks, isoform A	19		-	-	26.2
281	uncharacterized protein LOC108099255 isoform X3	19		-	-	17.6
282	Intersectin 2	19	3D	1uffA00	-	30.6
316	Myosin tail region-interacting protein MTI1	18	3D	1zukB00	-	74.6
286	Uncharacterized protein, isoform D	18		-	-	16.2
287	BAI1-associated protein 2-like 2b	18		-	-	79.0
285	Peptidase M24	18		-	-	0.0
284	Peptidase M24	18		-	-	0.0
290	Microtubule-actin cross-linking factor 1	16		-	-	35.3
291	Uncharacterized protein, isoform A	16		-	-	11.7
288	Calcium channel, voltage-dependent, beta 3b	16		-	-	60.1
289	Rho guanine nucleotide exchange factor GEF	16		-	-	18.9
296	Actin polymerization protein Bzz1	15		-	-	93.1
293	PhnA domain protein	15		-	-	56.4
294	Chemotaxis protein CheW	15		-	-	0.0
292	Calcium Channel, Beta subunit	15		-	-	18.1
295	Blast:Tyrosine-protein kinase Src-1	15		-	-	33.7
299	Endophilin B, isoform A	14		-	-	25.6
298	Rho GTPase-activating protein	14		-	-	55.0
297	CheA signal transduction histidine kinase	14		-	-	16.4
322	Myosin I	14	3D	1zuyB00	-	8.5
300	Actin cytoskeleton-regulatory complex protein SLA1	14		-	-	76.4
302	Abp1p	13		-	-	68.0
304	Sporulation protein	13		-	-	10.3
305	Nostrin, isoform H	13		-	-	6.5
301	SH3 domain-containing protein	13		-	-	3.9
306	Protein CBG22463	13		-	-	15.3
303	ZO-1 Zonula Occludens tight junctional protein	13		-	-	19.7
311	Polarized growth protein Boi2	12		-	-	38.2
313	SH3 domain protein	12		-	-	85.3
310	Actin polymerization protein Bzz1	12		-	-	46.5
309	Purine-binding chemotaxis protein CheW	12		-	-	0.0
308	Bud site selection protein	12		-	-	9.3
307	Predicted protein	12		-	-	97.1
312	Related to Cell division control protein 15	12		-	-	78.3
314	Unplaced genomic scaffold supercont1.257, whole genome shotgun sequence	12		-	-	67.6
323	Muscle M-line assembly protein unc-89	11		-	-	5.5
326	Alkylphosphonate utilization operon protein PhnA	11		-	-	14.8
321	JNK Interacting Protein Scaffold protein	11		-	-	0.0
356	Cell death abnormality protein 2	11	3D	3qwyB02	-	64.1
320	E3 ubiquitin-protein ligase hecd-1	11		-	-	25.2
325	Hof1p	11		-	-	19.1
318	Bud emergence protein 1	11		-	-	12.2
327	CIN85 and CD2AP related, isoform D	11		-	-	18.1
317	Bud emergence protein	11		-	-	12.3
315	Calcium channel, voltage-dependent, beta 2b	11		-	-	84.9
328	Actin cytoskeleton-regulatory complex protein sla1	11		-	-	80.8
324	SH3 domain-containing protein	11		-	-	77.8
319	CIN85 and CD2AP related, isoform C	11		-	-	12.6
330	Purine-binding chemotaxis protein CheW	10		-	-	0.0
331	Signal transducing adapter molecule 1	10		-	-	70.9
336	SH3 domain-containing protein 1	10		-	-	19.7
333	Predicted protein	10		-	-	81.9
337	Disks large homolog 1	10		-	-	48.9
335	Endolysin	10		-	-	7.8
334	Uncharacterized protein	10		-	-	11.9
332	Caspase recruitment domain family, member 11	10		-	-	47.0
329	Trio, isoform D	10		-	-	17.1
353	Neutrophil cytosol factor 2	9		-	-	72.6
351	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma	9		-	-	25.7
348	Unconventional myosin heavy chain 6	9		-	-	7.3
347	SH3 and cysteine rich domain	9		-	-	28.7
350	Sorting nexin	9		-	-	15.7
345	serine-rich adhesin for platelets isoform X2	9		-	-	11.0
342	Bzz1p	9		-	-	1.8
349	N-acetylmuramoyl-L-alanine amidase	9		-	-	11.9
344	Chemotaxis protein CheW	9		-	-	0.0
338	Transport and Golgi organization protein 1	9		-	-	52.4
346	GTPase-activating protein rrc-1	9		-	-	28.6
341	Nuclear fusion protein FUS1	9		-	-	1.5
343	Cell division cycle-related protein	9		-	-	11.9
340	Cytokinesis protein 3	9		-	-	1.9
339	Unplaced genomic scaffold supercont1.11, whole genome shotgun sequence	9		-	-	15.2
352	Putative chemotaxis protein CheV	9		-	-	40.6
354	Guanine nucleotide exchange factor UNC-73A	9		-	-	16.0
363	Bridging integrator 1	8		-	-	15.3
366	LIM and SH3 protein	8		-	-	59.8
361	Heavy chain, Unconventional Myosin	8		-	-	0.0
360	Peripheral plasma membrane protein CASK	8		-	-	5.6
355	Unplaced genomic scaffold supercont2.1, whole genome shotgun sequence	8		-	-	10.5
367	Variant sh3 domain containing protein	8		-	-	75.2
357	Crk oncogene, isoform B	8		-	-	2.0
365	Endophilin-A homolog	8		-	-	8.9
368	Chemotaxis protein CheW	8		-	-	88.5
358	Putative N-acetylmuramoyl-L-alanine amidase	8		-	-	42.2
362	Tyrosine-protein kinase	8		-	-	7.2
364	AMPHiphysin homolog	8		-	-	18.6
359	Tyrosine-protein kinase	8		-	-	34.9
378	Elongation factor 2 kinase	7		-	-	7.7
375	Putative purine-binding chemotaxis protein Chew	7		-	-	2.3
377	N-acetylmuramoyl-L-alanine amidase	7		-	-	1.8
372	Elongation factor 2 kinase	7		-	-	4.2
379	ITSN Intersectin	7		-	-	13.8
374	Putative purine-binding chemotaxis protein Chew	7		-	-	0.0
371	Protein arginine methyltransferase 2	7		-	-	68.0
376	N-acetylmuramoyl-L-alanine amidase	7		-	-	8.1
373	Putative purine-binding chemotaxis protein Chew	7		-	-	0.0
380	Variant sh3 domain containing protein	7		-	-	6.1
370	Plenty of SH3s	7		-	-	17.4
381	NCK Non-Catalytic region of tyrosine Kinase	7		-	-	22.6
369	Scaffold protein CheW associated with MCPs of classes 40H and 40+24H	7		-	-	35.8
385	Protein arginine N-methyltransferase 2	6		-	-	74.1
394	Proline-serine-threonine phosphatase-interacting protein 1b	6		-	-	43.9
404	Rho GTPase-activating protein 4	6	3D	2epdA00	-	56.2
387	ITSN Intersectin	6		-	-	0.0
399	Bridging integrator 2b	6		-	-	75.0
388	Uncharacterized protein	6		-	-	7.9
392	SMAll	6		-	-	0.0
395	Chemotaxis protein CheA	6		-	-	0.0
389	RAS p21 protein activator GTPase activating protein	6		-	-	17.5
397	Tyrosine-protein kinase	6		-	-	90.4
384	Alpha- 1,6	6		-	-	67.8
398	Hematopoietic cell-specific Lyn substrate 1	6		-	-	75.9
382	ABl Interactor homolog	6		-	-	14.4
383	Chemotaxis protein CheW	6		-	-	12.2
386	N-acetylmuramoyl-L-alanine amidase	6		-	-	2.1
400	Peripheral-type benzodiazepine receptor-associated protein 1	6		-	-	52.4
390	ITSN Intersectin	6		-	-	0.0
393	Uncharacterized protein, isoform C	6		-	-	5.5
391	ITSN Intersectin	6		-	-	0.0
396	Alkylphosphonate uptake protein	6		-	-	8.8
402	Protein CBG22463	5		-	-	24.6
405	small G protein signaling modulator 3 isoform X10	5		-	-	13.7
407	Related to YSC84-protein involved in the organization of actin cytoskeleton	5		-	-	76.1
403	Rho GTPase-activating protein 27,-like	5		-	-	53.9
406	Tyrosine-protein kinase	5		-	-	6.0
401	Calcium Channel, Beta subunit	5		-	-	18.6
420	Predicted protein	4		-	-	79.6
409	Uncharacterized protein	4		-	-	6.7
410	Chemotaxis protein CheW	4		-	-	0.0
413	Tyrosine-protein kinase	4		-	-	63.1
421	Predicted protein	4		-	-	78.3
411	Cell death abnormality protein 2	4		-	-	20.1
416	Neutrophil cytosolic factor 2	4		-	-	11.5
408	Peroxin 13	4		-	-	6.9
415	LIM and SH3 domain protein 2	4		-	-	34.8
417	Neutrophil cytosolic factor 4	4		-	-	9.1
418	Meiotically up-regulated gene 137 protein	4		-	-	85.0
414	Predicted protein	4		-	-	74.7
419	Chemotaxis protein CheV	4		-	-	8.9
412	Dynamin-binding protein	4		-	-	75.8
433	Predicted protein	3		-	-	76.1
445	Tyrosine-protein kinase	3		-	-	1.7
450	Uncharacterized protein	3		-	-	11.6
447	neutrophil cytosolic factor 1 isoform X1	3		-	-	1.9
436	Uncharacterized protein	3		-	-	8.9
431	Bud emergence protein, putative	3		-	-	9.2
448	PACSIN3 isoform 8	3		-	-	0.0
426	Peroxisomal membrane protein, putative	3		-	-	5.3
451	Tyrosine-protein kinase	3		-	-	34.0
423	Protein kinase C and casein kinase substrate in neurons 2	3		-	-	58.6
453	Tyrosine-protein kinase	3		-	-	58.0
430	Chemotaxis protein CheW	3		-	-	0.0
444	neutrophil cytosolic factor 1 isoform X1	3		-	-	3.3
449	SH3 domain-containing protein 2	3		-	-	1.6
442	rho GTPase-activating protein 27 isoform X1	3		-	-	13.4
428	Ras family guanine nucleotide exchange factor	3		-	-	1.8
427	Peroxin 13, putative	3		-	-	13.2
440	Variant sh3 domain containing protein	3		-	-	3.3
425	Fus1p	3		-	-	1.7
435	Uncharacterized protein	3		-	-	37.8
443	Tyrosine-protein kinase	3		-	-	1.6
437	Chromosome 16, whole genome shotgun sequence	3		-	-	13.8
441	Caspase recruitment domain family member 10	3		-	-	1.1
446	SH3 domain and tetratricopeptide repeat-containing protein 2	3		-	-	13.6
438	Tyrosine-protein kinase	3		-	-	13.6
429	Purine-binding chemotaxis protein CheW	3		-	-	0.0
424	Nephronophthisis 1	3		-	-	15.4
454	Uncharacterized protein	3		-	-	33.6
432	BAR domaincontaining protein	3		-	-	45.2
452	Tyrosine-protein kinase	3		-	-	4.9
422	voltage-dependent L-type calcium channel subunit beta-1 isoform X2	3		-	-	1.9
439	Uncharacterized protein	3		-	-	7.5
434	Tyrosine-protein kinase	3		-	-	27.4
509	Tyrosine-protein kinase	3	3D	1gl5A00	-	23.8
477	Scaffold protein CheW associated with MCPs of classes 40H and 40+24H	2		-	-	0.0
512	Alpha- 1,6	2		-	-	0.0
492	Uncharacterized protein	2		-	-	41.3
475	Cell division control protein 25	2		-	-	3.1
460	SH3 domain protein, conserved	2		-	-	0.0
501	Uncharacterized protein	2		-	-	0.0
506	Abl protein tyrosine kinase	2		-	-	0.0
534	Brain-specific angiogenesis inhibitor 1-associated protein 2	2		-	-	0.0
478	Purine-binding chemotaxis protein CheW	2		-	-	0.0
539	SH3 domain-containing protein	2		-	-	0.0
503	Uncharacterized protein	2		-	-	0.0
522	Disks large homolog 1	2		-	-	0.0
532	Protein kinase C and casein kinase substrate in neurons protein 2	2		-	-	33.3
488	Protein CBR-CED-5	2		-	-	0.0
500	Uncharacterized protein	2		-	-	0.0
461	Hematopoietic cell-specific Lyn substrate 1	2		-	-	0.0
466	Uncharacterized protein	2		-	-	0.0
524	Si:ch211-25d12.7	2		-	-	3.1
456	Putative voltage-dependent l-type calcium channel subunit beta-2	2		-	-	3.1
529	Epidermal growth factor receptor kinase substrate 8	2		-	-	0.0
487	Uncharacterized protein	2		-	-	46.0
519	Uncharacterized protein	2		-	-	8.5
499	BAR domaincontaining protein	2		-	-	4.1
514	Protein CBR-SMA-1	2		-	-	7.5
463	Uncharacterized protein	2		-	-	10.8
494	Predicted protein	2		-	-	50.3
485	Peripheral-type benzodiazepine receptor-associated protein 1	2		-	-	0.0
482	Uncharacterized protein	2		-	-	7.8
474	SLIT-ROBO Rho GTPase-activating protein 3	2		-	-	0.0
479	Scaffold protein CheW associated with MCPs of class 44H	2		-	-	0.0
538	SH3 domain-containing protein	2		-	-	0.0
541	Uncharacterized protein	2		-	-	2.5
537	Formin-binding protein	2		-	-	0.0
535	YALI0F19778p	2		-	-	0.0
543	Predicted protein	2		-	-	47.6
525	Teichoic acids export ATP-binding protein TagH	2		-	-	0.0
498	JNK-interacting protein 1	2		-	-	0.0
518	Tyrosine-protein kinase	2		-	-	0.0
540	Tyrosine-protein kinase	2		-	-	9.9
527	Plectin	2		-	-	11.7
472	Uncharacterized protein	2		-	-	0.0
484	Uncharacterized protein	2		-	-	0.0
489	Predicted protein	2		-	-	41.1
517	zinc finger protein ZZ-type	2		-	-	0.0
497	SH3 and multiple ankyrin repeat domains 2	2		-	-	32.8
495	Rho GTPase-activating protein gacJJ	2		-	-	23.7
515	Rho GTPase-activating protein 33	2		-	-	2.9
528	Tyrosine-protein kinase	2		-	-	13.8
458	Uncharacterized protein	2		-	-	42.1
542	EPS8 like 1	2		-	-	48.8
486	SH3 and PX domain-containing protein 2B	2		-	-	0.0
481	YALI0F27643p	2		-	-	0.0
468	Uncharacterized protein	2		-	-	1.7
470	F-BAR and double SH3 domains protein 2 isoform X6	2		-	-	0.0
465	Uncharacterized protein	2		-	-	9.3
457	Probable peroxisomal membrane protein PEX13	2		-	-	35.2
467	SH3 domain-containing YSC84-like protein 1	2		-	-	0.0
455	Uncharacterized protein	2		-	-	35.6
483	Protein app1	2		-	-	0.0
480	Positive regulator of CheA protein activity CheW	2		-	-	7.7
508	Uncharacterized protein	2		-	-	0.0
473	RIM Binding protein	2		-	-	0.0
507	Predicted protein	2		-	-	0.0
544	Uncharacterized protein	2		-	-	49.5
476	Chemotaxis signal transduction system adaptor protein CheW	2		-	-	2.1
471	ACR266Wp	2		-	-	3.5
505	BAR domaincontaining protein	2		-	-	0.0
530	BAR domaincontaining protein	2		-	-	1.9
502	BAR domaincontaining protein	2		-	-	7.9
523	BAR domaincontaining protein	2		-	-	1.7
496	Uncharacterized protein	2		-	-	14.2
516	zinc finger protein ZZ-type	2		-	-	0.0
491	Tyrosine-protein kinase	2		-	-	47.5
511	Small G protein signaling modulator 3	2		-	-	0.0
459	SH3 and SYLF domain containing 1	2		-	-	0.0
526	LysM peptidoglycan-binding domain-containing protein	2		-	-	0.0
521	phosphatidylinositol 3-kinase regulatory subunit gamma	2		-	-	0.0
513	Uncharacterized protein	2		-	-	0.0
464	Cytokinesis and cell polarization-associated protein, putative	2		-	-	2.1
493	Predicted protein	2		-	-	39.5
469	SH3 and F-BAR domain-containing protein DDB_G0271676	2		-	-	30.1
490	Predicted protein	2		-	-	0.0
510	N-acetylmuramoyl-L-alanine amidase	2		-	-	7.2
462	Uncharacterized protein	2		-	-	0.0
531	BAR domaincontaining protein	2		-	-	5.8
536	F-BAR and double SH3 domains protein 2	2		-	-	0.0
504	Dynamin-binding protein	2		-	-	0.0
520	Tyrosine-protein kinase	2		-	-	8.9
533	AaceriABR082Wp	2		-	-	0.0
545	AGAP000255-PE	2		-	-	51.6
638	Tyrosine-protein kinase	1		-	-	0.0
676	Predicted protein	1		-	-	0.0
671	Predicted protein	1		-	-	0.0
641	Uncharacterized protein	1		-	-	0.0
646	Tyrosine-protein kinase	1		-	-	0.0
562	Uncharacterized protein	1		-	-	0.0
637	Uncharacterized protein	1		-	-	0.0
673	Uncharacterized protein	1		-	-	0.0
552	Uncharacterized protein	1		-	-	0.0
680	Uncharacterized protein	1		-	-	0.0
590	Predicted protein	1		-	-	0.0
635	Uncharacterized protein	1		-	-	0.0
643	Protein vav-1	1		-	-	0.0
640	Mindbomb E3 ubiquitin protein ligase 2	1		-	-	0.0
667	Uncharacterized protein	1		-	-	0.0
569	Uncharacterized protein	1		-	-	0.0
564	Uncharacterized protein	1		-	-	0.0
593	Tyrosine-protein kinase	1		-	-	0.0
625	Src like adaptor 2	1		-	-	0.0
655	Rho GTPase-activating protein 27	1		-	-	0.0
683	Predicted protein	1		-	-	0.0
618	Discs, large homolog 4a Drosophila	1		-	-	0.0
670	Uncharacterized protein	1		-	-	0.0
665	Uncharacterized protein	1		-	-	0.0
554	Bbc1p	1		-	-	0.0
657	Tyrosine-protein kinase	1		-	-	0.0
559	Si:dkey-40c11.2	1		-	-	0.0
627	MAGUK p55 subfamily member 7	1		-	-	0.0
617	Uncharacterized protein	1		-	-	0.0
591	Rho GTPase-activating protein gacII	1		-	-	0.0
596	Predicted protein	1		-	-	0.0
681	Variant SH3 domain containing protein	1		-	-	0.0
668	Uncharacterized protein	1		-	-	0.0
658	Predicted protein	1		-	-	0.0
615	Probable serine/threonine-protein kinase mkcF	1		-	-	0.0
628	Wu:fi04e12	1		-	-	0.0
571	Uncharacterized protein	1		-	-	0.0
612	Dynamin binding protein	1		-	-	0.0
576	Cdc42 guanine nucleotide exchange factor GEF	1		-	-	0.0
546	Calcium channel, voltage-dependent, beta 3 subunit	1		-	-	0.0
606	Uncharacterized protein	1		-	-	0.0
601	Uncharacterized protein	1		-	-	0.0
573	Uncharacterized protein	1		-	-	0.0
639	Tyrosine-protein kinase	1		-	-	0.0
662	Glycoprotein 6-alpha-L-fucosyltransferase, putative	1		-	-	0.0
634	Glutamate 5-kinase	1		-	-	0.0
580	Chemotaxis protein	1		-	-	0.0
652	Uncharacterized protein	1		-	-	0.0
603	Uncharacterized protein	1		-	-	0.0
622	Src kinase associated phosphoprotein 1	1		-	-	0.0
664	Uncharacterized protein	1		-	-	0.0
600	Uncharacterized protein	1		-	-	0.0
555	Putative truncated guanine nucleotide exchange factor YLL017W	1		-	-	0.0
583	Protein CBR-DLG-1	1		-	-	0.0
632	Uncharacterized protein	1		-	-	0.0
669	Predicted protein	1		-	-	0.0
567	Rho GTPase-activating protein 10	1		-	-	0.0
659	Uncharacterized protein	1		-	-	0.0
557	Uncharacterized protein	1		-	-	0.0
629	Uncharacterized protein	1		-	-	0.0
570	Protein csh3	1		-	-	0.0
565	C-terminal Src kinase	1		-	-	0.0
624	Uncharacterized protein	1		-	-	0.0
654	Small G protein signaling modulator 3	1		-	-	0.0
614	SH3 and multiple ankyrin repeat domains 3	1		-	-	0.0
581	Uncharacterized protein	1		-	-	0.0
568	Peroxisomal membrane protein PEX13-like Protein	1		-	-	0.0
586	Uncharacterized protein	1		-	-	0.0
619	Rho GTPase-activating protein 9	1		-	-	0.0
558	Predicted protein	1		-	-	0.0
602	Uncharacterized protein	1		-	-	0.0
623	Predicted protein	1		-	-	0.0
595	Uncharacterized protein	1		-	-	0.0
653	Uncharacterized protein	1		-	-	0.0
630	EPS8-like 3a	1		-	-	0.0
589	CD2-associated protein like	1		-	-	0.0
597	Uncharacterized protein	1		-	-	0.0
663	Uncharacterized protein	1		-	-	0.0
611	Predicted protein	1		-	-	0.0
572	Variant SH3 domain containing protein	1		-	-	0.0
616	Uncharacterized protein	1		-	-	0.0
584	Uncharacterized protein	1		-	-	0.0
621	Uncharacterized protein	1		-	-	0.0
626	Uncharacterized protein	1		-	-	0.0
651	Tyrosine-protein kinase PR2-like Protein	1		-	-	0.0
656	Discs large MAGUK scaffold protein 4	1		-	-	0.0
613	Uncharacterized protein	1		-	-	0.0
661	Uncharacterized protein	1		-	-	0.0
666	Predicted protein	1		-	-	0.0
598	Uncharacterized protein	1		-	-	0.0
610	Chemotaxis protein CheZ	1		-	-	0.0
648	Tyrosine-protein kinase sid-3	1		-	-	0.0
636	Si:dkey-40c11.2	1		-	-	0.0
631	Uncharacterized protein	1		-	-	0.0
678	Uncharacterized protein	1		-	-	0.0
647	Uncharacterized protein	1		-	-	0.0
549	Discs, large homolog 4	1		-	-	0.0
675	Uncharacterized protein	1		-	-	0.0
604	Predicted protein	1		-	-	0.0
660	Tyrosine-protein kinase	1		-	-	0.0
609	Rho GTPase-activating protein 4	1		-	-	0.0
579	AEL241Wp	1		-	-	0.0
633	Predicted protein	1		-	-	0.0
677	Uncharacterized protein	1		-	-	0.0
645	Myosin-1	1		-	-	0.0
650	Tyrosine-protein kinase	1		-	-	0.0
582	Uncharacterized protein	1		-	-	0.0
620	Predicted protein	1		-	-	0.0
574	Uncharacterized protein	1		-	-	0.0
642	Uncharacterized protein	1		-	-	0.0
585	CD2-associated protein like	1		-	-	0.0
553	SH3 domain protein, conserved	1		-	-	0.0
672	Protein CBG04143	1		-	-	0.0
563	Uncharacterized protein	1		-	-	0.0
594	Uncharacterized protein	1		-	-	0.0
587	Uncharacterized protein	1		-	-	0.0
599	Uncharacterized protein	1		-	-	0.0
556	Cortactin, putative	1		-	-	0.0
551	Uncharacterized protein	1		-	-	0.0
566	Predicted protein	1		-	-	0.0
588	CIN85 and CD2AP related, isoform E	1		-	-	0.0
561	Variant SH3 domain containing protein	1		-	-	0.0
548	Predicted protein	1		-	-	0.0
608	Tyrosine-protein kinase	1		-	-	0.0
578	Chemotaxis signal transduction protein	1		-	-	0.0
607	Uncharacterized protein	1		-	-	0.0
644	Predicted protein	1		-	-	0.0
649	Uncharacterized protein	1		-	-	0.0
547	Uncharacterized protein	1		-	-	0.0
575	Predicted protein	1		-	-	0.0
560	Uncharacterized protein	1		-	-	0.0
682	Tyrosine-protein kinase	1		-	-	0.0
550	Calcium voltage-gated channel auxiliary subunit beta 3	1		-	-	0.0
605	Uncharacterized protein	1		-	-	0.0
674	Uncharacterized protein	1		-	-	0.0
592	Uncharacterized protein	1		-	-	0.0
577	Protein ste6	1		-	-	0.0
679	Variant SH3 domain containing protein	1		-	-	0.0

Network disruptions

CATH Superfamily 2.30.30.40

SH3 Domains

Functional Families

Browse Functional Families