The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
SH3 Domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 137: Uncharacterized protein, isoform G

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
12 A0A0B4K6C7 (/IPI) A0A0B4K6Y7 (/IPI) A8JQV7 (/IPI) A8JQV8 (/IPI) B7Z0U1 (/IPI) Q7K4E2 (/IPI) Q8INQ0 (/IPI) Q8MQQ3 (/IPI) Q94880 (/IPI) Q9VHK1 (/IPI)
(2 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8MQQ3 (/IPI)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Regulation of embryonic cell shape GO:0016476
Any process that modulates the surface configuration of an embryonic cell.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
12 A0A0B4K6C7 (/IGI) A0A0B4K6Y7 (/IGI) A8JQV7 (/IGI) A8JQV8 (/IGI) B7Z0U1 (/IGI) Q7K4E2 (/IGI) Q8INQ0 (/IGI) Q8MQQ3 (/IGI) Q94880 (/IGI) Q9VHK1 (/IGI)
(2 more)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Fusion cell fate specification GO:0035156
The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Nephrocyte diaphragm assembly GO:0036059
The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
12 A0A0B4K6C7 (/IMP) A0A0B4K6Y7 (/IMP) A8JQV7 (/IMP) A8JQV8 (/IMP) B7Z0U1 (/IMP) Q7K4E2 (/IMP) Q8INQ0 (/IMP) Q8MQQ3 (/IMP) Q94880 (/IMP) Q9VHK1 (/IMP)
(2 more)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
1 A0A0B4K6Y7 (/HMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 A0A0B4K6Y7 (/IGI)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 A0A0B4K6Y7 (/IMP)
Positive regulation of Notch signaling pathway GO:0045747
Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
1 A0A0B4K6Y7 (/IMP)
Negative regulation of endocytosis GO:0045806
Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
1 A0A0B4K6Y7 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Nephrocyte diaphragm GO:0005917
A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
12 A0A0B4K6C7 (/IDA) A0A0B4K6Y7 (/IDA) A8JQV7 (/IDA) A8JQV8 (/IDA) B7Z0U1 (/IDA) Q7K4E2 (/IDA) Q8INQ0 (/IDA) Q8MQQ3 (/IDA) Q94880 (/IDA) Q9VHK1 (/IDA)
(2 more)
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