The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tumor Necrosis Factor Receptor, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1934
3D
4m4rE03 - 96.8
2
277 - - 87.0
4
211
3D
3tjeF02 - 92.7
3
193 - - 86.2
5
180 - - 72.6
6
153 - - 81.1
7
149
3D
4rsuL01 - 95.2
9
140
3D
4rsuL02 - 97.2
8
133 - - 62.4
10
128
3D
4yn0A01 - 74.7
11
118
3D
4yn0A02 - 91.8
12
108
3D
3ij2Y02 - 67.7
17
106
3D
5cirG01 - 69.8
14
103
3D
3urfZ02 - 68.6
13
102
3D
3ij2Y01 - 66.3
15
93
3D
5bnqR02 - 40.5
16
92
3D
1du3G02 - 92.4
19
79
3D
5bnqR01 - 29.1
18
78 - - 97.1
20
76
3D
1tnrR01 - 87.1
21
69
3D
3tjeF01 - 70.9
25
68
3D
1tnrR02 - 88.1
26
63
3D
2heyT02 - 91.0
22
63 - - 64.4
23
63 - - 34.5
24
63 - - 72.9
27
56 - - 84.0
28
48 - - 45.8
31
46
3D
3alqW01 - 51.1
29
45 - - 84.5
30
44
3D
3urfZ01 - 77.5
32
37 - - 91.0
36
37
3D
3alqW02 - 82.5
33
36 - - 82.4
34
34 - - 37.8
35
34
3D
4mxwR02 - 50.1
43
33
3D
5ihlH01 - 47.5
37
31 - - 61.1
38
31
3D
2heyT01 - 79.6
39
28 - - 77.0
40
27 - - 88.8
41
26 - - 86.7
42
23 - - 43.4
44
21 - - 9.2
46
20 - - 12.7
45
20 - - 47.0
47
20 - - 89.6
48
19 - - 9.9
51
19 - - 5.2
53
19 - - 82.9
81
19
3D
5l36B01 - 16.6
49
19 - - 11.4
50
19 - - 9.9
52
19 - - 1.9
54
19 - - 34.2
56
18 - - 3.6
55
18 - - 3.9
60
17 - - 19.8
62
17 - - 6.9
58
17 - - 6.5
61
17 - - 10.3
63
17 - - 73.8
57
17 - - 2.1
59
17 - - 14.9
64
16 - - 18.1
74
14
3D
3qd6U02 - 12.6
65
13 - - 85.2
66
13 - - 10.6
69
12 - - 2.0
71
12 - - 71.8
67
12 - - 27.9
68
12 - - 4.2
70
12 - - 64.6
72
11 - - 15.2
73
11 - - 45.6
76
10 - - 87.1
77
10 - - 41.4
75
10 - - 85.8
78
9 - - 38.1
80
9 - - 4.6
79
9 - - 47.3
82
8 - - 73.5
84
6 - - 34.0
85
6 - - 41.7
87
6 - - 85.7
83
6 - - 0.0
86
6 - - 95.3
89
5 - - 52.0
92
5 - - 43.7
90
5 - - 75.6
91
5 - - 78.3
93
5 - - 0.0
88
5 - - 76.9
96
4 - - 2.1
94
4 - - 6.1
98
4 - - 79.1
95
4 - - 2.0
97
4 - - 10.8
105
3 - - 0.0
99
3 - - 8.4
103
3 - - 82.9
102
3 - - 0.0
100
3 - - 8.3
101
3 - - 0.0
104
3 - - 0.0
112
2 - - 0.0
129
2 - - 3.1
124
2 - - 0.0
131
2 - - 3.5
119
2 - - 43.1
110
2 - - 48.5
126
2 - - 10.6
133
2 - - 0.0
117
2 - - 48.0
109
2 - - 0.0
121
2 - - 0.0
107
2 - - 19.4
130
2 - - 0.0
115
2 - - 0.0
123
2 - - 11.8
128
2 - - 0.0
132
2 - - 0.0
111
2 - - 9.4
113
2 - - 0.0
125
2 - - 2.2
118
2 - - 46.8
134
2 - - 45.7
127
2 - - 6.6
116
2 - - 40.5
108
2 - - 3.3
120
2 - - 43.5
106
2 - - 7.8
122
2 - - 5.4
114
2 - - 0.0
170
1 - - 0.0
165
1 - - 0.0
168
TNFR superfamily, member 16
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
141
1 - - 0.0
163
1 - - 0.0
143
1 - - 0.0
137
1 - - 0.0
154
1 - - 0.0
147
1 - - 0.0
135
1 - - 0.0
145
1 - - 0.0
152
1 - - 0.0
160
1 - - 0.0
167
1 - - 0.0
140
1 - - 0.0
150
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
169
1 - - 0.0
172
1 - - 0.0
142
1 - - 0.0
158
1 - - 0.0
149
1 - - 0.0
139
1 - - 0.0
144
1 - - 0.0
156
1 - - 0.0
171
1 - - 0.0
166
1 - - 0.0
153
1 - - 0.0
136
1 - - 0.0
155
1 - - 0.0
161
1 - - 0.0
174
1 - - 0.0
146
1 - - 0.0
164
1 - - 0.0
151
1 - - 0.0
138
1 - - 0.0
173
1 - - 0.0