CATH Superfamily 1.20.5.170

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Tropomyosin alpha-1 chain isoform 1	2246	3D	2b9cB00	-	94.9
2	Type I keratin KA11	2183	3D	1gk4F00	-	91.3
3	cAMP-responsive element modulator isoform X2	1506	3D	1dh3C00	-	84.2
4	Keratin, type II cytoskeletal 5	1390	3D	3tnuB00	-	86.0
5	Tropomyosin alpha-1 chain	1237	3D	1kqlB00	-	93.6
6	fos-related antigen 2 isoform X1	1057	3D	2wt7A00	-	94.9
7	hepatic leukemia factor isoform X2	852		-	-	85.4
8	probable global transcription activator SNF2L2 isoform X1	773		-	-	77.7
9	probable transcription factor PosF21	758		-	-	84.5
10	Cyclic AMP-dependent transcription factor ATF-2	744	3D	1t2kD00	-	96.3
11	Transcription factor MafG, putative	607	3D	3a5tB00	-	90.0
12	Putative transcription factor AP-1	563	3D	1a02J00	-	81.9
13	RUN and FYVE domain-containing 1	530		-	-	85.1
14	Spectrin alpha chain, non-erythrocytic 1	507	3D	1owaA01	-	75.0
15	ARF GTPase-activating protein GIT2 isoform 1	473	3D	2w6aB00	-	84.4
16	MAF bZIP transcription factor	457	3D	4auwF00	-	75.7
17	Putative E3 ubiquitin-protein ligase TRIM9	447		-	-	86.2
18	AAA ATPase forming ring-shaped complexes	439	3D	3m9hF00	-	84.5
19	BZIP family transcription factor	394		-	-	83.7
20	BZIP transcription factor	371		-	-	98.7
21	Cyclic AMP-dependent transcription factor ATF-4	356	3D	1ci6A00	-	95.9
22	Tripartite motif containing 55	352	3D	4m3lD00	-	87.0
23	ADP-ribosylation factor-binding protein GGA3 isoform X1	348	3D	1oxzA01	-	78.3
28	CCAAT/enhancer-binding protein beta	344	3D	6mg3B00	-	81.8
24	VHS domain-containing protein	337		-	-	77.2
25	nuclear factor interleukin-3-regulated protein-like	336		-	-	93.8
26	Calcium-transporting ATPase	332		-	-	92.7
27	Tripartite motif-containing 46, isoform CRA_c	326		-	-	61.7
29	Calcium-transporting ATPase	313	3D	4aqrD00	-	84.5
30	RUN and FYVE domain-containing protein 2 isoform X1	302		-	-	63.7
31	BZIP transcription factor MeaB	296		-	-	76.7
33	Lamin A/C	288	3D	3v5bA00	-	65.2
32	UDP-3-O- 3-hydroxymyristoyl	284	3D	3eh0C03	-	60.0
34	Nucleoporin P54, putative	250	3D	4jo7H00	-	95.4
35	TNF receptor-associated factor	249	3D	3m0dB00	-	92.8
36	ABSCISIC ACID-INSENSITIVE 5-like protein 2	235		-	-	88.3
38	Short coiled-coil protein a	226	3D	4bwdC00	-	61.7
37	cyclic AMP-responsive element-binding protein 3-like protein 2	225		-	-	51.2
39	Autophagy-related protein 16-1 isoform 1	212		-	-	95.9
40	Nuclear pore glycoprotein p62	212		-	-	100.0
41	Cyclic AMP-dependent transcription factor ATF-6 beta	209		-	-	83.0
42	Cyclic AMP-responsive element-binding protein 3-like protein 3	198		-	-	79.2
43	Basic leucine zipper transcriptional factor ATF-like	196		-	-	74.5
44	cAMP-responsive element-binding protein-like 2 isoform X2	195		-	-	54.9
45	nuclear pore glycoprotein p62	191	3D	3t97C00	-	72.2
46	cGMP-dependent protein kinase 1	188	3D	3nmdE00	-	45.6
47	male-specific lethal 1 homolog isoform X1	186	3D	4b86F00	-	91.1
48	ABSCISIC ACID-INSENSITIVE 5-like protein 5	173		-	-	63.4
49	X-box binding protein 1	167		-	-	75.7
50	E3 ubiquitin-protein ligase RNF8	154	3D	4aycA01	-	84.2
51	mitotic spindle assembly checkpoint protein MAD1	147	3D	4dzoB01	-	85.3
52	GDP-mannose 6-dehydrogenase	146	3D	1mv8D02	-	38.7
53	BZIP transcription factor AtfA	138		-	-	95.3
55	CCAAT/enhancer-binding protein gamma	122		-	-	81.4
56	DNA repair protein SWI5 homolog	122	3D	3virC00	-	90.2
54	Cyclic AMP-responsive element-binding protein 3-like 2	122		-	-	71.6
57	Basic leucine zipper 61	113		-	-	57.6
58	Intermediate filament protein B	112		-	-	97.7
59	unconventional myosin-X	105	3D	2lw9B00	-	42.5
62	Sodium/potassium-transporting ATPase subunit beta	98	3D	4xe5B01	-	75.8
60	protein ABSCISIC ACID-INSENSITIVE 5 isoform X1	94		-	-	60.5
61	Sodium/potassium-transporting ATPase subunit beta	91		-	-	93.0
73	Voltage-gated hydrogen channel 1	87	3D	3a2aD00	-	83.6
63	G-box binding factor 3	86		-	-	80.8
64	fibronectin type III and SPRY domain-containing protein 1	83		-	-	31.7
65	Keratin, type II cytoskeletal 80	83		-	-	77.4
67	BZIP transcription factor	79	3D	1gd2I00	-	80.0
66	DNA damage-inducible transcript 3 protein	74		-	-	68.9
69	cGMP-gated cation channel alpha-1	73	3D	3swfB00	-	90.5
68	Sodium/potassium-transporting ATPase subunit beta	72		-	-	79.7
70	CREB/ATF bZIP transcription factor	69		-	-	40.5
71	Neural retina-specific leucine zipper protein	69		-	-	95.7
72	Putative chromatin structure-remodeling complex subunit snf21	67		-	-	73.4
74	Spindle assembly checkpoint component	65		-	-	77.2
75	BZIP transcription factor MetR	56		-	-	72.1
77	LAO/AO transport system kinase	55	3D	2p67A01	-	20.2
78	Methylmalonic aciduria type A homolog, mitochondrial	55	3D	2wwwD01	-	59.8
76	Lamin B2	54		-	-	45.2
79	Outer capsid protein VP4	53	3D	1slqF02	-	36.8
81	Nestin	47		-	-	89.8
80	Basic leucine zipper transcriptional factor ATF-like 2	47		-	-	77.3
82	Cell death specification	45		-	-	79.5
83	Transcription factor VIP1	42		-	-	59.6
84	Mitotic spindle assembly checkpoint protein MAD1	40		-	-	15.4
85	bZIP transcription factor 49	39		-	-	72.0
86	Transcription factor VIP1	34		-	-	84.9
87	FOS like 1, AP-1 transcription factor subunit	33		-	-	62.1
88	cyclic nucleotide-gated cation channel alpha-4	31		-	-	36.0
89	Putative global transcription activator SNF2L2	31		-	-	66.3
90	Propionate catabolism operon regulatory protein PrpR	30		-	-	6.0
91	CD207 isoform 1	27	3D	3kqgA01	-	47.5
92	Basic-leucine zipper transcription factor	26		-	-	52.2
95	Transcription factor SPN1	24	3D	3nfqB01	-	39.7
93	BZIP transcription factor Eurofung	24		-	-	75.6
94	Beaded filament structural protein 1	23		-	-	68.7
96	BZIP transcription factor bZIP46	22		-	-	76.1
97	Beaded filament structural protein 2	22		-	-	25.8
98	Basic leucine zipper 24	21		-	-	50.6
99	Uncharacterized protein	20		-	-	53.8
101	BZIP transcription factor HacA	20		-	-	73.2
100	ATP-dependent helicase BRM	20		-	-	41.1
103	tropomyosin alpha-1 chain isoform X10	19		-	-	19.8
102	bZIP transcription factor hapX	19		-	-	56.8
107	Uncharacterized protein	18		-	-	73.0
104	Probable SNF2-component of SWI/SNF global transcription activator complex	18		-	-	40.4
105	AP-1-like transcription factor YAP4	18		-	-	72.6
106	Chromatin structure-remodeling complex subunit snf21	18		-	-	81.7
109	ATF cAMP-dependent transcription factor	17		-	-	71.0
111	CCAAT/enhancer-binding protein	17		-	-	13.8
108	SYNM isoform 4	17		-	-	34.8
110	BZIP-type transcription factor	17		-	-	35.9
115	Peptide chain release factor subunit 1	16	3D	3ir9B01	-	79.1
112	testis-specific serine kinase substrate	16		-	-	12.0
114	Tropomyosin	14		-	-	50.3
113	Sth1p	14		-	-	32.6
116	Transcription regulatory protein SNF2	14	3D	4i6mC00	-	62.0
117	Positive regulator of galactose inducible genes	13		-	-	2.2
122	Oncoprotein MEQ	13		-	-	20.2
119	ATF cAMP-dependent transcription factor	13		-	-	29.4
120	CREB Homolog	13		-	-	41.4
118	Adhesin	13		-	-	21.5
123	Basic region/leucine zipper protein	13		-	-	78.0
121	Transcription factor jun-1	13		-	-	17.2
126	Unplaced genomic scaffold supercont1.19, whole genome shotgun sequence	12		-	-	8.3
127	Protein CBR-ATF-2	12		-	-	70.9
125	LAS1-like, ribosome biogenesis factor	12		-	-	79.5
124	Alcohol dehydrogenase 3	12		-	-	11.6
128	Citron rho-interacting serine/threonine kinase b	11		-	-	21.9
133	Uncharacterized protein	11		-	-	47.0
131	Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence	11		-	-	9.8
130	Transcription factor VIP1 isoform A	11		-	-	26.6
129	Heme-responsive zinc finger transcription factor HAP1	11		-	-	0.0
132	BZIP transcription factor family	11		-	-	19.8
135	Transcriptional activator in the Cbf1p-Met4p-Met28p complex	10		-	-	6.1
143	Structural maintenance of chromosomes	10	3D	3htkA00	-	0.0
134	Transcription factor	10		-	-	0.0
137	Unplaced genomic scaffold supercont2.16, whole genome shotgun sequence	10		-	-	14.5
139	Arr1p	10		-	-	9.3
138	ATF cAMP-dependent transcription factor	10		-	-	53.3
153	Trans-activator protein BZLF1	10	3D	2c9nZ00	-	16.9
140	BZIP transcription factor family	10		-	-	95.1
136	Proto-oncogene c-Fos	10		-	-	1.8
141	C6 transcription factor Gal4	9		-	-	24.7
144	Male-specific lethal-1	9		-	-	12.2
145	ATG16-domain-containing protein	9		-	-	53.7
147	fos-related antigen 2 isoform X1	9		-	-	17.9
146	Atg16p	9		-	-	0.0
142	CCR4-associated factor 4	9		-	-	1.8
149	LD42070p	8		-	-	38.8
152	Yap3p	8		-	-	0.0
150	AP-1-like transcription factor YAP7	8		-	-	6.6
151	Putative Cyclic AMP-dependent transcription factor ATF-3	8		-	-	0.0
148	Nuclear pore complex protein Nup54	8		-	-	5.5
156	Uncharacterized protein	7		-	-	60.3
158	BZIP transcription factor family	7		-	-	93.2
160	C/EBP CCAAT/enhancer-binding protein	7		-	-	14.8
161	Tropomyosin 3	7		-	-	63.3
159	Serologically defined colon cancer antigen	7		-	-	12.5
157	DNA repair protein Swi5/Sae3	7		-	-	74.8
155	CREB/ATF bZIP transcription factor	7		-	-	78.7
154	Cgmp-dependent protein kinase	7		-	-	16.4
166	Activating transcription factor-2	6		-	-	5.9
168	AP-1-like transcription factor YAP2	6		-	-	3.4
162	SPeCtrin	6		-	-	11.9
163	Uncharacterized protein	6		-	-	13.6
164	Protein Mabiki	6		-	-	3.3
165	Pachytene arrest protein SAE3	6		-	-	3.4
167	UDP-3-O-acylglucosamine N-acyltransferase	6		-	-	50.5
173	Slo1p	5		-	-	0.0
171	Related to spindle assembly checkpoint protein	5		-	-	16.5
174	Predicted protein	5		-	-	90.6
183	Desiccation-related protein At2g46140	5	3D	1yycA01	-	8.6
175	Basic-leucine zipper transcription factor B	5		-	-	53.2
176	Aureochrome 1	5		-	-	73.9
169	Predicted protein	5		-	-	92.0
172	BZIP transcription factor 2	5		-	-	12.6
170	GM14169p	5		-	-	9.5
179	Autophagy-related protein 16 isoform A	4		-	-	38.0
190	Cyclic AMP-responsive element-binding protein	4		-	-	17.7
187	Transcription factor fos-1	4		-	-	53.3
185	BZIP transcription factor	4		-	-	35.6
192	RSC chromatin remodeling complex ATPase subunit	4		-	-	45.7
184	Stress activated transcription factor atfs-1	4		-	-	24.6
177	Laminin subunit alpha 3	4		-	-	52.3
189	Uncharacterized protein	4		-	-	9.3
181	C-type lectin domain family 4 member F	4		-	-	29.5
182	C-type lectin domain family 4 member F	4		-	-	12.8
188	X-box Binding Protein homolog	4		-	-	41.5
180	C-type lectin domain family 4 member F	4		-	-	27.6
186	Basic-leucine zipper BZIP	4		-	-	36.7
178	C-type lectin domain family 4 member F	4		-	-	17.2
191	FOS-like antigen 1b	4		-	-	74.8
203	Basic leucine zipper transcriptional factor ATF-like	3		-	-	3.4
201	Filament-like plant protein 6	3		-	-	8.1
198	BZIP transcription factor	3		-	-	18.5
204	tropomyosin, smooth muscle/fibroblast CTM1-like isoform X1	3		-	-	2.7
196	AGAP006031-PA-like protein	3		-	-	6.9
195	Intermediate filament protein ifb-2	3		-	-	7.9
194	Sodium/potassium-transporting ATPase subunit beta	3		-	-	8.4
197	C-type lectin domain family 4 member F	3		-	-	6.3
200	Putative basic-leucine zipper transcription factor	3		-	-	11.6
193	Tropomyosin-1, isoforms 9A/A/B-like Protein	3		-	-	37.1
202	Transcription factor AP-1	3		-	-	7.4
199	Glial fibrillary acidic protein	3		-	-	18.8
239	nuclear pore glycoprotein p62-like	2		-	-	0.0
211	Tropomyosin	2		-	-	0.0
247	Uncharacterized protein	2		-	-	0.0
250	Predicted protein	2		-	-	40.4
213	Galactose-responsive transcription factor	2		-	-	0.0
220	Mitotic checkpoint protein MAD1	2		-	-	8.7
228	Predicted protein	2		-	-	43.8
233	Probable basic-leucine zipper transcription factor G	2		-	-	7.9
231	Uncharacterized protein	2		-	-	12.4
245	FBJ murine osteosarcoma viral oncogene homolog B	2		-	-	0.0
222	Paramyosin, putative	2		-	-	5.8
219	p-loop containing nucleoside triphosphate hydrolases superfamily protein	2		-	-	0.0
209	cyclic nucleotide-gated channel rod photoreceptor subunit alpha-like isoform X1	2		-	-	2.1
244	X-box-binding protein 1	2		-	-	0.0
205	Uncharacterized protein	2		-	-	7.0
215	Putative nucleoporin Nup54-like Protein	2		-	-	0.0
237	Transcription factor MafB	2		-	-	1.1
249	Uncharacterized protein	2		-	-	46.4
214	Voltage-gated hydrogen channel 1	2		-	-	0.0
234	Cyclic AMP-responsive element-binding protein 3-like protein 1	2		-	-	0.0
217	Uncharacterized protein	2		-	-	0.0
235	Tropomyosin	2		-	-	0.8
226	SNF2-family ATP dependent chromatin remodeling factor snf21	2		-	-	0.0
241	transcription factor protein isoform X1	2		-	-	2.0
243	Transcription factor VBP	2		-	-	0.0
207	Protein tipD	2		-	-	25.5
224	SNF2 family N-terminal domain-domain-containing protein	2		-	-	0.0
242	Transcription factor MafG, putative	2		-	-	6.3
236	AP-1-like transcription factor YAP7	2		-	-	0.0
225	Uncharacterized protein	2		-	-	0.0
248	Uncharacterized protein	2		-	-	21.7
240	Cyclic AMP-dependent transcription factor ATF-4	2		-	-	0.0
206	Sodium/potassium-transporting ATPase subunit beta-2-like Protein	2		-	-	54.4
227	BZIP transcription factor bZIP44	2		-	-	32.7
216	Nuclear pore complex protein Nup54	2		-	-	0.0
238	AP-1-like transcription factor YAP5	2		-	-	0.0
210	Male-specific lethal 1-like protein	2		-	-	0.0
223	YALI0D23287p	2		-	-	0.0
221	Transcription factor AP-1	2		-	-	0.0
246	UPF0612 protein C569.003	2		-	-	0.0
232	Predicted protein	2		-	-	5.1
229	Uncharacterized protein	2		-	-	1.6
212	GTPase activator protein	2		-	-	0.0
230	Putative basic region leucine zipper transcription factor	2		-	-	8.8
218	Predicted protein	2		-	-	0.0
208	Calcium-transporting ATPase	2		-	-	3.7
262	Uncharacterized protein	1		-	-	0.0
275	Uncharacterized protein	1		-	-	0.0
283	Uncharacterized protein	1		-	-	0.0
281	Uncharacterized protein	1		-	-	0.0
296	Uncharacterized protein	1		-	-	0.0
268	Uncharacterized protein	1		-	-	0.0
274	Uncharacterized protein	1		-	-	0.0
258	Uncharacterized protein	1		-	-	0.0
289	Uncharacterized protein	1		-	-	0.0
260	Uncharacterized protein	1		-	-	0.0
277	Uncharacterized protein	1		-	-	0.0
301	Tropomyosin 3	1		-	-	0.0
252	Uncharacterized protein	1		-	-	0.0
284	Hepatic leukemia factor-like protein	1		-	-	0.0
298	Uncharacterized protein	1		-	-	0.0
266	Uncharacterized protein	1		-	-	0.0
292	JunB proto-oncogene, AP-1 transcription factor subunit a	1		-	-	0.0
273	Uncharacterized protein	1		-	-	0.0
285	Uncharacterized protein	1		-	-	0.0
271	Uncharacterized protein	1		-	-	0.0
287	Keratin, type I cytoskeletal 14	1		-	-	0.0
279	Uncharacterized protein	1		-	-	0.0
290	Uncharacterized protein	1		-	-	0.0
256	Uncharacterized protein	1		-	-	0.0
270	Uncharacterized protein	1		-	-	0.0
299	Uncharacterized protein	1		-	-	0.0
254	Uncharacterized protein	1		-	-	0.0
267	Predicted protein	1		-	-	0.0
255	AFL160Cp	1		-	-	0.0
257	Uncharacterized protein	1		-	-	0.0
265	Viral A-type inclusion protein, putative	1		-	-	0.0
272	Chromosome 1, whole genome shotgun sequence	1		-	-	0.0
293	cAMP-responsive element modulator a	1		-	-	0.0
291	Protein CBG22431	1		-	-	0.0
286	Uncharacterized protein	1		-	-	0.0
264	Tropomyosin-1, isoforms 9A/A/B-like Protein	1		-	-	0.0
278	Uncharacterized protein	1		-	-	0.0
251	Predicted protein	1		-	-	0.0
253	Uncharacterized protein	1		-	-	0.0
297	Uncharacterized protein	1		-	-	0.0
269	ADR293C-Ap	1		-	-	0.0
280	Uncharacterized protein	1		-	-	0.0
259	Mitotic spindle assembly checkpoint protein MAD1-like Protein	1		-	-	0.0
294	Predicted protein	1		-	-	0.0
288	Uncharacterized protein	1		-	-	0.0
300	Uncharacterized protein	1		-	-	0.0
276	Uncharacterized protein	1		-	-	0.0
295	Activating transcription factor 5	1		-	-	0.0
282	Uncharacterized protein	1		-	-	0.0
261	cGMP-dependent protein kinase	1		-	-	0.0
263	Uncharacterized protein	1		-	-	0.0

Network disruptions

Functional Families

Browse Functional Families