CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
1.20.5.170 |
Domain Context
CATH Clusters
| Superfamily | 1.20.5.170 |
| Functional Family | Calcium-transporting ATPase |
Enzyme Information
| 7.2.2.10 |
P-type Ca(2+) transporter.
based on mapping to UniProt Q9LF79
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum, in yeast, and in some bacteria. -!- The enzymes from plasma membrane and from yeast have been shown to transport one ion per ATP hydrolyzed whereas those from the sarcoplasmic reticulum transport two ions per ATP hydrolyzed. -!- In muscle cells Ca(2+) is transported from the cytosol into the sarcoplasmic reticulum. -!- Formerly EC 3.6.1.38 and EC 3.6.3.8.
|
UniProtKB Entries (1)
| P59220 |
CALM7_ARATH
Arabidopsis thaliana
Calmodulin-7
|
PDB Structure
| PDB | 4AQR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A Bimodular Mechanism of Calcium Control in Eukaryotes
Nature
|
