The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Death Domain, Fas
".
FunFam 91: NLR family pyrin domain containing 10
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q86W26 (/IDA) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q86W26 (/IDA) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of T-helper 1 type immune response GO:0002827
Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
|
2 | Q8CCN1 (/IMP) Q8CCN1 (/IMP) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
2 | Q8CCN1 (/RCA) Q8CCN1 (/RCA) |
|
Positive regulation of interleukin-1 alpha secretion GO:0050717
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Positive regulation of interleukin-1 alpha secretion GO:0050717
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
|
2 | Q8CCN1 (/IMP) Q8CCN1 (/IMP) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
2 | Q8CCN1 (/IMP) Q8CCN1 (/IMP) |
|
Positive regulation of defense response to bacterium GO:1900426
Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Positive regulation of defense response to bacterium GO:1900426
Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Positive regulation of T-helper 17 type immune response GO:2000318
Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.
|
2 | Q8CCN1 (/IMP) Q8CCN1 (/IMP) |
|
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Positive regulation of T-helper 1 type immune response GO:0002827
Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
|
1 | Q86W26 (/ISS) |
|
Positive regulation of interleukin-1 alpha secretion GO:0050717
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
|
1 | Q86W26 (/IMP) |
|
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
|
1 | Q86W26 (/ISS) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | Q86W26 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q86W26 (/ISS) |
|
Positive regulation of defense response to bacterium GO:1900426
Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
|
1 | Q86W26 (/IMP) |
|
Positive regulation of T-helper 17 type immune response GO:2000318
Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.
|
1 | Q86W26 (/ISS) |
|
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
|
1 | Q86W26 (/IMP) |
|
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
|
1 | Q86W26 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
2 | Q8CCN1 (/ISO) Q8CCN1 (/ISO) |
|
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
2 | Q8CCN1 (/ISS) Q8CCN1 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q86W26 (/IDA) |
|
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
1 | Q86W26 (/IDA) |
