The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Death Domain, Fas
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 122: Caspase 8a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Induction by virus of host apoptotic process GO:0019051
The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.
5 A0A2U9DQK9 (/IMP) F1QLH0 (/IMP) Q56VC8 (/IMP) Q66I19 (/IMP) Q9I8J3 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
5 A0A2U9DQK9 (/IDA) F1QLH0 (/IDA) Q56VC8 (/IDA) Q66I19 (/IDA) Q9I8J3 (/IDA)
Regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281
Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.
5 A0A2U9DQK9 (/IGI) F1QLH0 (/IGI) Q56VC8 (/IGI) Q66I19 (/IGI) Q9I8J3 (/IGI)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
CATH-Gene3D is a Global Biodata Core Resource Learn more...