CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1140 | Ribosomal protein S3 C-terminal domain |
|
3.30.1140.32 | Ribosomal protein S3, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Ribosomal protein S3, C-terminal domain |
| Functional Family | 40S ribosomal protein S3 |
Enzyme Information
| 4.2.99.18 |
DNA-(apurinic or apyrimidinic site) lyase.
based on mapping to UniProt P23396
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
-!- 'Nicking' of the phosphodiester bond is due to a lyase-type reaction, not hydrolysis. -!- This group of enzymes was previously listed as endonucleases, under the number EC 3.1.25.2.
|
UniProtKB Entries (1)
| P15880 |
RS2_HUMAN
Homo sapiens
40S ribosomal protein S2
|
PDB Structure
| PDB | 5A2Q |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution
Nat.Commun.
|
