PDB 5h7o

PDB Information

PDB5H7O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSus scrofa
Primary Citation
A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Arnst, K.E., Wang, Y., Hwang, D.J., Xue, Y., Costello, T., Hamilton, D., Chen, Q., Yang, J., Park, F., Dalton, J.T., Miller, D.D., Li, W.
Cancer Res.
HeaderStructural Protein
Released2016-11-20
Resolution2.800
CATH Insert Date07 Jan, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped
C 07 Jan, 2018 Chopped
D 07 Jan, 2018 Chopped
E 07 Jan, 2018 Chopped
F 07 Jan, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5h7oA01 11 Jan, 2018 3.40.50.1440 Assigned
5h7oA02 11 Jan, 2018 3.30.1330.20 Assigned
5h7oA03 11 Jan, 2018 1.10.287.600 Assigned
5h7oB01 11 Jan, 2018 3.40.50.1440 Assigned
5h7oB02 11 Jan, 2018 3.30.1330.20 Assigned
5h7oB03 11 Jan, 2018 1.10.287.600 Assigned
5h7oC01 11 Jan, 2018 3.40.50.1440 Assigned
5h7oC02 11 Jan, 2018 3.30.1330.20 Assigned
5h7oC03 11 Jan, 2018 1.10.287.600 Assigned
5h7oD01 11 Jan, 2018 3.40.50.1440 Assigned
5h7oD02 11 Jan, 2018 3.30.1330.20 Assigned
5h7oD03 11 Jan, 2018 1.10.287.600 Assigned
5h7oE01 11 Jan, 2018 6.10.280.30 Assigned
5h7oF01 11 Jan, 2018 3.40.50.11480 Assigned
5h7oF02 11 Jan, 2018 3.30.470.20 Assigned
5h7oF03 11 Jan, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein