CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.11480 |
Domain Context
CATH Clusters
Superfamily | 3.40.50.11480 |
Functional Family | tubulin--tyrosine ligase |
Enzyme Information
UniProtKB Entries (4)
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
P63043 |
STMN4_RAT
Rattus norvegicus
Stathmin-4
|
Q2XVP4 |
TBA1B_PIG
Sus scrofa
Tubulin alpha-1B chain
|
Q6B856 |
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain
|
PDB Structure
PDB | 5H7O |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Cancer Res.
|