CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family

Enzyme Information

UniProtKB Entries (4)

E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
P63043
STMN4_RAT
Rattus norvegicus
Stathmin-4
Q2XVP4
TBA1B_PIG
Sus scrofa
Tubulin alpha-1B chain
Q6B856
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain

PDB Structure

PDB 5H7O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Arnst, K.E., Wang, Y., Hwang, D.J., Xue, Y., Costello, T., Hamilton, D., Chen, Q., Yang, J., Park, F., Dalton, J.T., Miller, D.D., Li, W.
Cancer Res.