CATH Superfamily 2.40.290.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 3: RNA-binding motif protein 15
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q0VBL3 (/IPI) Q6PHZ5 (/IPI) Q8NDT2 (/IPI) Q8NDT2 (/IPI) Q96T37 (/IPI) Q96T37 (/IPI) Q96T37 (/IPI) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
6 | Q0VBL3 (/IDA) Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | Q8NDT2 (/HDA) Q8NDT2 (/HDA) Q96T37 (/HDA) Q96T37 (/HDA) Q96T37 (/HDA) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
3 | Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q8NDT2 (/NAS) Q8NDT2 (/NAS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q6PHZ5 (/ISS) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q0VBL3 (/ISO) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q0VBL3 (/ISS) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
6 | Q0VBL3 (/IDA) Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
|
5 | Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
Dosage compensation by inactivation of X chromosome GO:0009048
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.
|
5 | Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
Thrombopoietin-mediated signaling pathway GO:0038163
A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | Q96T37 (/ISS) Q96T37 (/ISS) Q96T37 (/ISS) |
Regulation of megakaryocyte differentiation GO:0045652
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
|
3 | Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
RNA methylation GO:0001510
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
|
2 | Q0VBL3 (/ISS) Q6PHZ5 (/ISS) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
2 | Q8NDT2 (/ISS) Q8NDT2 (/ISS) |
Dosage compensation by inactivation of X chromosome GO:0009048
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
Dosage compensation by inactivation of X chromosome GO:0009048
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.
|
2 | Q0VBL3 (/ISS) Q6PHZ5 (/ISS) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q0VBL3 (/IDA) |
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
|
1 | Q6PHZ5 (/ISS) |
Branching involved in blood vessel morphogenesis GO:0001569
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
|
1 | Q0VBL3 (/IMP) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
1 | Q6PHZ5 (/IDA) |
Positive regulation of transcription of Notch receptor target GO:0007221
The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.
|
1 | Q0VBL3 (/IDA) |
Thrombopoietin-mediated signaling pathway GO:0038163
A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q0VBL3 (/IDA) |
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
1 | Q0VBL3 (/IDA) |
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
1 | Q0VBL3 (/IMP) |
Regulation of megakaryocyte differentiation GO:0045652
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
|
1 | Q0VBL3 (/ISO) |
Spleen development GO:0048536
The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
|
1 | Q0VBL3 (/IMP) |
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
1 | Q0VBL3 (/IMP) |
Placenta blood vessel development GO:0060674
The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.
|
1 | Q0VBL3 (/IMP) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | A0A087WWP4 (/IDA) A0A087WWP4 (/IDA) Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
6 | Q6PHZ5 (/IDA) Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
RNA N6-methyladenosine methyltransferase complex GO:0036396
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
|
5 | Q8NDT2 (/IDA) Q8NDT2 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) Q96T37 (/IDA) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
3 | Q6PHZ5 (/IDA) Q8NDT2 (/IDA) Q8NDT2 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
RNA N6-methyladenosine methyltransferase complex GO:0036396
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
|
2 | Q0VBL3 (/ISO) Q6PHZ5 (/ISO) |
RNA N6-methyladenosine methyltransferase complex GO:0036396
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
|
2 | Q0VBL3 (/ISS) Q6PHZ5 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q0VBL3 (/IDA) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q6PHZ5 (/ISO) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q6PHZ5 (/ISS) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | Q6PHZ5 (/ISS) |