The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Isoleucyl-tRNA Synthetase; Domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
350 - - 75.1
3
295
3D
4cqnD04 - 84.9
2
288 - - 98.5
4
267 - - 92.5
5
258
3D
3h9cA03 - 91.3
6
229
3D
1f7vA02 - 98.2
7
223 - - 77.5
8
175
3D
2zufA03 - 98.1
9
167 - - 94.5
10
156 - - 85.2
11
152 - - 96.9
12
143 - - 93.3
13
127 - - 52.6
14
125 - - 91.4
15
120 - - 78.0
16
114 - - 74.3
17
109 - - 71.2
18
107 - - 70.0
19
99 - - 86.6
82
92
3D
5v49B03 - 63.8
21
87 - - 63.1
20
87 - - 93.4
22
78 - - 96.3
23
68 - - 85.9
25
64 - - 74.4
24
64 - - 78.9
26
57 - - 93.2
27
46 - - 73.1
28
44 - - 74.7
29
43 - - 43.3
30
39 - - 53.7
31
39 - - 94.6
33
34 - - 97.6
35
34
3D
6ax8A03 - 68.8
32
34 - - 17.9
34
33 - - 10.8
36
28 - - 26.3
38
26 - - 80.7
37
26 - - 93.9
39
24 - - 27.0
40
23 - - 82.2
43
23
3D
2ct8B03 - 81.0
41
23 - - 22.6
42
19 - - 9.6
44
18 - - 13.6
45
17 - - 54.2
51
16
3D
1wz2B03 - 87.9
46
16 - - 0.8
47
16 - - 24.5
48
15 - - 12.2
50
15 - - 15.5
49
15 - - 0.0
53
13 - - 57.1
52
13 - - 0.0
55
12 - - 0.0
54
12 - - 2.6
56
11 - - 0.0
57
11 - - 0.0
61
11 - - 8.7
63
11 - - 37.5
58
11 - - 5.4
60
11 - - 79.1
62
11 - - 36.6
64
11 - - 86.7
59
11 - - 8.5
67
10 - - 25.5
66
10 - - 0.0
65
10 - - 67.9
68
10 - - 3.7
69
10 - - 59.0
73
9 - - 30.3
70
9 - - 1.9
71
9 - - 10.1
72
9 - - 66.6
78
7 - - 10.5
84
7 - - 62.0
76
7 - - 3.9
75
7 - - 72.5
77
7 - - 13.4
79
7 - - 0.0
83
7 - - 77.5
80
7 - - 3.1
74
7 - - 7.9
81
7 - - 9.7
89
6 - - 21.7
91
6 - - 1.5
90
6 - - 21.9
88
6 - - 37.5
92
6 - - 77.5
86
6 - - 54.2
85
6 - - 88.0
87
6 - - 12.2
100
5 - - 13.0
95
5 - - 0.0
96
5 - - 6.9
97
5 - - 0.0
101
5 - - 6.0
93
5 - - 10.5
105
5 - - 11.2
98
5 - - 11.9
103
5 - - 14.2
104
5 - - 10.1
107
5 - - 57.4
94
5 - - 1.0
102
5 - - 61.0
106
5 - - 0.9
99
5 - - 0.0
115
4 - - 46.2
113
putative
4 - - 9.4
111
4 - - 63.6
108
4 - - 85.5
118
4 - - 5.2
110
4 - - 4.0
112
4 - - 0.0
109
4 - - 8.7
116
4 - - 10.0
117
4 - - 2.5
114
4 - - 5.2
126
3 - - 0.6
130
3 - - 63.7
122
3 - - 0.0
127
3 - - 35.4
131
3 - - 18.2
124
3 - - 0.0
133
3 - - 61.8
129
3 - - 0.0
125
3 - - 1.3
123
3 - - 0.0
134
3 - - 27.9
121
3 - - 3.0
128
3 - - 1.9
119
3 - - 0.0
132
3 - - 0.0
120
3 - - 35.1
173
2 - - 39.2
175
2 - - 41.0
163
2 - - 0.0
165
2 - - 0.0
155
AFU_orthologue AFUA_6G04910
2 - - 0.0
149
2 - - 43.2
153
2 - - 0.0
151
2 - - 0.0
138
2 - - 0.0
161
2 - - 0.0
171
2 - - 0.0
144
2 - - 0.0
168
2 - - 10.8
158
2 - - 0.0
147
2 - - 7.1
170
2 - - 0.0
146
2 - - 0.0
135
2 - - 0.0
150
2 - - 0.0
160
2 - - 0.0
142
2 - - 9.0
166
2 - - 0.0
152
2 - - 1.6
139
2 - - 0.0
140
2 - - 12.4
162
2 - - 1.3
156
2 - - 0.0
172
2 - - 38.7
176
2 - - 43.5
167
2 - - 0.7
157
2 - - 34.5
148
2 - - 59.7
164
2 - - 5.7
137
2 - - 0.0
154
2 - - 0.0
141
2 - - 0.0
174
2 - - 41.6
136
2 - - 0.0
143
2 - - 5.4
145
2 - - 3.4
159
2 - - 0.0
169
2 - - 0.0
216
1 - - 0.0
194
1 - - 0.0
188
1 - - 0.0
212
1 - - 0.0
223
1 - - 0.0
209
1 - - 0.0
225
1 - - 0.0
221
1 - - 0.0
180
1 - - 0.0
204
1 - - 0.0
217
1 - - 0.0
199
1 - - 0.0
234
1 - - 0.0
183
1 - - 0.0
185
1 - - 0.0
228
1 - - 0.0
196
1 - - 0.0
214
1 - - 0.0
207
1 - - 0.0
237
1 - - 0.0
192
1 - - 0.0
178
1 - - 0.0
220
1 - - 0.0
206
1 - - 0.0
232
1 - - 0.0
197
1 - - 0.0
202
1 - - 0.0
181
1 - - 0.0
219
1 - - 0.0
236
1 - - 0.0
213
1 - - 0.0
222
1 - - 0.0
230
1 - - 0.0
215
1 - - 0.0
226
1 - - 0.0
200
1 - - 0.0
184
1 - - 0.0
198
1 - - 0.0
190
1 - - 0.0
227
1 - - 0.0
208
1 - - 0.0
211
1 - - 0.0
189
1 - - 0.0
177
1 - - 0.0
193
1 - - 0.0
195
1 - - 0.0
224
1 - - 0.0
186
1 - - 0.0
218
1 - - 0.0
231
1 - - 0.0
201
1 - - 0.0
182
1 - - 0.0
229
1 - - 0.0
203
1 - - 0.0
205
1 - - 0.0
210
1 - - 0.0
235
1 - - 0.0
233
1 - - 0.0
179
1 - - 0.0
187
1 - - 0.0
191
1 - - 0.0
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