CATH Domain 5zeaI02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	V-type proton ATPase catalytic subunit A

Enzyme Information

7.2.2.1

Na(+)-transporting two-sector ATPase.

based on mapping to UniProt Q08636

ATP + H(2)O + n Na(+)(Side 1) = ADP + phosphate + n Na(+)(Side 2).

-!- A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis. -!- The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). -!- Cf. EC 7.2.2.3 and EC 7.2.2.4. -!- Formerly EC 3.6.3.15.

UniProtKB Entries (1)

Q08637

NTPB_ENTHA

Enterococcus hirae ATCC 9790

V-type sodium ATPase subunit B

PDB Structure

PDB	5ZEA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Metastable asymmetrical structure of a shaftless V1motor. Maruyama, S., Suzuki, K., Imamura, M., Sasaki, H., Matsunami, H., Mizutani, K., Saito, Y., Imai, F.L., Ishizuka-Katsura, Y., Kimura-Someya, T., Shirouzu, M., Uchihashi, T., Ando, T., Yamato, I., Murata, T. Sci Adv

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