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1 keywords

CATH Domain 5vxzB02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.200  

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Growth arrest specific 6

Enzyme Information

UniProtKB Entries (1)

Q14393
GAS6_HUMAN
Homo sapiens
Growth arrest-specific protein 6

PDB Structure

PDB 5VXZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.
Kariolis, M.S., Miao, Y.R., Diep, A., Nash, S.E., Olcina, M.M., Jiang, D., Jones, D.S., Kapur, S., Mathews, I.I., Koong, A.C., Rankin, E.B., Cochran, J.R., Giaccia, A.J.
J. Clin. Invest.
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