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1 keywords

CATH Domain 5nofB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1030 Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
Homologous Superfamily 3.40.1030.10 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family Anthranilate phosphoribosyltransferase

Enzyme Information

2.4.2.18
Anthranilate phosphoribosyltransferase.
based on mapping to UniProt Q9YGB4
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

Q9YGB4
TRPD_THEKO
Thermococcus kodakarensis KOD1
Anthranilate phosphoribosyltransferase

PDB Structure

PDB 5NOF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Anthranilate phosphoribosyltransferase from the hyperthermophilic archaeon Thermococcus kodakarensis shows maximum activity with zinc and forms a unique dimeric structure.
Perveen, S., Rashid, N., Tang, X.F., Imanaka, T., Papageorgiou, A.C.
FEBS Open Bio
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