×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 5ipfD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Hypoxanthine phosphoribosyltransferase

Enzyme Information

2.4.2.8
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt P09383
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.

UniProtKB Entries (1)

P09383
HPRT_SCHMA
Schistosoma mansoni
Hypoxanthine-guanine phosphoribosyltransferase

PDB Structure

PDB 5IPF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases.
Romanello, L., Zeraik, A.E., de Freitas Fernandes, A., Torini, J.R., Bird, L.E., Nettleship, J.E., Rada, H., Reddivari, Y., Owens, R.J., Serrao, V.H.B., DeMarco, R., Brandao-Neto, J., Pereira, H.D.
Mol. Biochem. Parasitol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...