CATH Domain 4twdA01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.170	Acetylcholine Binding Protein; Chain: A,
	2.70.170.10	Neurotransmitter-gated ion-channel ligand-binding domain

Domain Context

CATH Clusters

Superfamily	Neurotransmitter-gated ion-channel ligand-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

ELIC_DICCH

Dickeya chrysanthemi

Cys-loop ligand-gated ion channel

PDB Structure

PDB	4TWD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Ulens, C., Spurny, R., Thompson, A.J., Alqazzaz, M., Debaveye, S., Han, L., Price, K., Villalgordo, J.M., Tresadern, G., Lynch, J.W., Lummis, S.C. Structure