CATH Domain 4j2yB02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P86451	ITRY_ENTCO Enterolobium contortisiliquum Trypsin inhibitor
P00760	TRY1_BOVIN Bos taurus Cationic trypsin

PDB Structure

PDB	4J2Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin. Zhou, D., Lobo, Y.A., Batista, I.F., Marques-Porto, R., Gustchina, A., Oliva, M.L., Wlodawer, A. Plos One