CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Collagenase 3 |
Enzyme Information
| 3.4.24.22 |
Stromelysin 2.
based on mapping to UniProt P09238
Similar to stromelysin 1, but action on collagen types III, IV and V is weak.
-!- Digests gelatin types I, III, IV, V, fibronectin and proteoglycan. -!- Belongs to peptidase family M10B.
|
UniProtKB Entries (1)
| P09238 |
MMP10_HUMAN
Homo sapiens
Stromelysin-2
|
PDB Structure
| PDB | 4ILW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes.
Plos One
|
