CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1970 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1970 |
| Functional Family | Alcohol dehydrogenase, iron-containing |
Enzyme Information
| 1.1.1.1 |
Alcohol dehydrogenase.
based on mapping to UniProt P0DJA2
(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
|
UniProtKB Entries (1)
| P0DJA2 |
ADH2_ZYMMO
Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821
Alcohol dehydrogenase 2
|
PDB Structure
| PDB | 3OWO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor
J.Mol.Biol.
|
