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1 keywords

CATH Domain 2pywB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.1200 Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2
Homologous Superfamily 3.90.1200.10 Aminoglycoside phosphotransferase (APH), C-terminal lobe

Domain Context

CATH Clusters

Superfamily 3.90.1200.10
Functional Family Methylthioribose kinase

Enzyme Information

2.7.1.100
S-methyl-5-thioribose kinase.
based on mapping to UniProt Q9C6D2
ATP + S-methyl-5-thio-D-ribose = ADP + S-methyl-5-thio-alpha-D-ribose 1-phosphate.
-!- Also acts, more slowly, on CTP.

UniProtKB Entries (1)

Q9C6D2
MTK_ARATH
Arabidopsis thaliana
Methylthioribose kinase

PDB Structure

PDB 2PYW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of A. thaliana 5-methylthioribose kinase in complex with ADP and MTR reveals a more occluded active site than its bacterial homolog
Ku, S.Y., Cornell, K.A., Howell, P.L.
Bmc Struct.Biol.
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