CATH Domain 2gtpD01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.196	Regulator of G-protein Signalling 4; domain 1
	1.10.196.10

Domain Context

CATH Clusters

Superfamily	1.10.196.10
Functional Family	Regulator of G-protein signaling 1

Enzyme Information

UniProtKB Entries (1)

GNAI1_HUMAN

Homo sapiens

Guanine nucleotide-binding protein G(i) subunit alpha-1

PDB Structure

PDB	2GTP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Soundararajan, M., Willard, F.S., Kimple, A.J., Turnbull, A.P., Ball, L.J., Schoch, G.A., Gileadi, C., Fedorov, O.Y., Dowler, E.F., Higman, V.A., Hutsell, S.Q., Sundstrom, M., Doyle, D.A., Siderovski, D.P. Proc.Natl.Acad.Sci.Usa