CATH Domain 1z83A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Adenylate kinase 1

Enzyme Information

2.7.4.3	Adenylate kinase. based on mapping to UniProt P00568 ATP + AMP = 2 ADP. -!- Inorganic triphosphate can also act as donor.
2.7.4.6	Nucleoside-diphosphate kinase. based on mapping to UniProt P00568 ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. -!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

KAD1_HUMAN

Homo sapiens

Adenylate kinase isoenzyme 1

PDB Structure

PDB	1Z83
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of human AK1A in complex with AP5A Filippakopoulos, P., Bunkoczi, G., Jansson, A., Schreurs, A., Knapp, S., Edwards, A., von Delft, F., Sundstrom, M. To be Published