CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.240 | QueA-like |
Domain Context
CATH Clusters
| Superfamily | QueA-like |
| Functional Family | S-adenosylmethionine:tRNA ribosyltransferase-isomerase |
Enzyme Information
| 2.4.99.17 |
S-adenosylmethionine:tRNA ribosyltransferase-isomerase.
based on mapping to UniProt O32054
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.
-!- The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. -!- It is part of the queuosine biosynthesis pathway.
|
UniProtKB Entries (1)
| O32054 |
QUEA_BACSU
Bacillus subtilis subsp. subtilis str. 168
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
|
PDB Structure
| PDB | 1YY3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Biochem.Biophys.Res.Commun.
|
