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CATH Classification

Domain Context

CATH Clusters

Superfamily Luciferase-like domain
Functional Family 5,10-methylenetetrahydromethanopterin reductase

Enzyme Information

1.5.98.2
5,10-methylenetetrahydromethanopterin reductase.
based on mapping to UniProt Q50744
5-methyltetrahydromethanopterin + oxidized coenzyme F420 = 5,10- methylenetetrahydromethanopterin + reduced coenzyme F420.
-!- Catalyzes an intermediate step in methanogenesis from CO(2) and H(2) in archaea. -!- Formerly EC 1.5.99.11.

UniProtKB Entries (1)

Q50744
MER_METTM
Methanothermobacter marburgensis str. Marburg
5,10-methylenetetrahydromethanopterin reductase

PDB Structure

PDB 1F07
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of coenzyme F(420) dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea.
Shima, S., Warkentin, E., Grabarse, W., Sordel, M., Wicke, M., Thauer, R.K., Ermler, U.
J.Mol.Biol.
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