CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Ribosomal RNA large subunit methyltransferase J |
Enzyme Information
| 2.1.1.266 |
23S rRNA (adenine(2030)-N(6))-methyltransferase.
based on mapping to UniProt P37634
S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L- homocysteine + N(6)-methyladenine(2030) in 23S rRNA.
-!- The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits.
|
UniProtKB Entries (1)
| P37634 |
RLMJ_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase J
|
PDB Structure
| PDB | 6QE5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites.
Rna Biol.
|
