CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Pentafunctional AROM polypeptide |
Enzyme Information
| 1.1.1.25 |
Shikimate dehydrogenase.
based on mapping to UniProt B0XRM8
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
|
| 4.2.3.4 |
3-dehydroquinate synthase.
based on mapping to UniProt B0XRM8
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
-!- The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products. -!- Formerly EC 4.6.1.3.
|
| 4.2.1.10 |
3-dehydroquinate dehydratase.
based on mapping to UniProt B0XRM8
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
|
| 2.7.1.71 |
Shikimate kinase.
based on mapping to UniProt B0XRM8
ATP + shikimate = ADP + shikimate 3-phosphate.
|
| 2.5.1.19 |
3-phosphoshikimate 1-carboxyvinyltransferase.
based on mapping to UniProt B0XRM8
Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O- (1-carboxyvinyl)-3-phosphoshikimate.
|
UniProtKB Entries (1)
| B0XRM8 |
ARO1_ASPFC
Aspergillus fumigatus A1163
Pentafunctional AROM polypeptide
|
PDB Structure
| PDB | 5SWU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Dehydroquinate dehydratase from A. fumigatus AroM
To Be Published
|