CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Glucan 1,4-alpha-glucosidase SusB |
Enzyme Information
| 3.2.1.3 |
Glucan 1,4-alpha-glucosidase.
based on mapping to UniProt G8JZS4
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose.
-!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.
|
UniProtKB Entries (1)
| G8JZS4 |
SUSB_BACTN
Bacteroides thetaiotaomicron VPI-5482
Glucan 1,4-alpha-glucosidase SusB
|
PDB Structure
| PDB | 3WFA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase
To be Published
|