CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Tagatose 1,6-diphosphate aldolase 2 |
Enzyme Information
| 4.1.2.40 |
Tagatose-bisphosphate aldolase.
based on mapping to UniProt Q5HE13
D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
-!- Enzyme activity is stimulated by certain divalent cations. -!- Involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria.
|
UniProtKB Entries (1)
| Q5HE13 |
LACD_STAAC
Staphylococcus aureus subsp. aureus COL
Tagatose 1,6-diphosphate aldolase
|
PDB Structure
| PDB | 3MYP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of LacD from Staphylococcus aureus and LacD.1 from Streptococcus pyogenes: Insights into substrate specificity and virulence gene regulation
Febs Lett.
|