CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1010 | 5'-nuclease |
Domain Context
CATH Clusters
| Superfamily | 5'-nuclease |
| Functional Family | Ribonuclease VapC |
Enzyme Information
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt P9WFB9
|
UniProtKB Entries (1)
| O07227 |
VAPB2_MYCTU
Mycobacterium tuberculosis H37Rv
Antitoxin VapB2
|
PDB Structure
| PDB | 3H87 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site.
Protein Sci.
|