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1 keywords

CATH Domain 2ddsA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.60 4-Layer Sandwich
Topology 3.60.10 Deoxyribonuclease I; Chain A
Homologous Superfamily 3.60.10.10 Endonuclease/exonuclease/phosphatase

Domain Context

CATH Clusters

Superfamily Endonuclease/exonuclease/phosphatase
Functional Family Sphingomyelinase C

Enzyme Information

3.1.4.12
Sphingomyelin phosphodiesterase.
based on mapping to UniProt P11889
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
-!- Has very little activity on phosphatidylcholine.

UniProtKB Entries (1)

P11889
PHL2_BACCE
Bacillus cereus
Sphingomyelinase C

PDB Structure

PDB 2DDS
External Links
Method X-RAY DIFFRACTION
Organism Bacillus
Primary Citation
Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
Ago, H., Oda, M., Takahashi, M., Tsuge, H., Ochi, S., Katunuma, N., Miyano, M., Sakurai, J.
J.Biol.Chem.
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