CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquitin Conjugating Enzyme
Functional Family NEDD8-conjugating enzyme Ubc12

Enzyme Information

2.3.2.-
Aminoacyltransferases.
based on mapping to UniProt P61081

UniProtKB Entries (1)

Q8TBC4
UBA3_HUMAN
Homo sapiens
NEDD8-activating enzyme E1 catalytic subunit

PDB Structure

PDB 1Y8X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Huang, D.T., Paydar, A., Zhuang, M., Waddell, M.B., Holton, J.M., Schulman, B.A.
Mol.Cell