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CATH Superfamily 6.10.280.210

Dsl1p vesicle tethering complex, Tip20p subunit, domain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dsl1p vesicle tethering complex, Tip20p subunit, domain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Dsl1p vesicle tethering complex, Tip20p subunit, domain A

This superfamily includes domain A of the Tip20p subunit, Dsl1p vesicle tethering complex, whose three subunits are essential for trafficking from the Golgi apparatus to the ER. Two of the three subunits, Tip20p and Dsl1p, resemble known subunits of the exocyst complex, establishing a structural connection among several multi-subunit tethering complexes and implying that many of their subunits are derived from a common progenitor. The structure of Tip20p consists entirely of alpha-helices and intervening loops of variable length, organised into a series of helix bundle domains.

DOI:10.1038/nsmb.1548

GO Diversity

Unique GO annotations
5 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
48 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 5
Taxonomy
Unique Species: 48