The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Bacterial extracellular solute-binding protein, family 7

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Bacterial extracellular solute-binding protein, family 7

This superfamily is involved in binding extracellular solutes for transport across the bacterial cytoplasmic membrane. This family includes P37735 a C4-dicarboxylate-binding protein and the sialic acid-binding protein SiaP. The structure of the SiaP receptor has revealed an overall topology similar to ATP binding cassette ESR (extracytoplasmic solute receptors) proteins. Upon binding of sialic acid, SiaP undergoes domain closure about a hinge region and kinking of an alpha-helix hinge component.


GO Diversity

Unique GO annotations
16 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
6831 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 206
Domain clusters (>95% seq id): 75
Domain clusters (>35% seq id): 37
Unique PDBs: 107
Structural Clusters (5A): 2
Structural Clusters (9A): 2
FunFam Clusters: 18
Unique EC:
Unique GO: 16
Unique Species: 6831